CA2813515C - Presentation de recepteurs pour l'antigene des lymphocytes t - Google Patents
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- CA2813515C CA2813515C CA2813515A CA2813515A CA2813515C CA 2813515 C CA2813515 C CA 2813515C CA 2813515 A CA2813515 A CA 2813515A CA 2813515 A CA2813515 A CA 2813515A CA 2813515 C CA2813515 C CA 2813515C
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Landscapes
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Particule protéique, p. ex. un bactériophage, un ribosome ou une cellule présentant à sa surface un récepteur pour l'antigène des lymphocytes T (TCR). De préférence, le TCR présenté est un hétérodimère qui comporte une liaison disulfure non native entre des résidus du domaine constant. Lesdites particules de présentation peuvent être utilisées pour créer diverses bibliothèques de TCR afin de recenser des TCR à affinité élevée. Plusieurs affinités élevées sont décrites.
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0226227A GB0226227D0 (en) | 2002-11-09 | 2002-11-09 | Receptors |
| GB0226227.7 | 2002-11-09 | ||
| GB0301814A GB0301814D0 (en) | 2003-01-25 | 2003-01-25 | Substances |
| GB0301814.0 | 2003-01-25 | ||
| GB0304067.2 | 2003-02-22 | ||
| GB0304067A GB0304067D0 (en) | 2003-02-22 | 2003-02-22 | Substances |
| US46304603P | 2003-04-16 | 2003-04-16 | |
| US60/463,046 | 2003-04-16 | ||
| GB0311397A GB0311397D0 (en) | 2003-05-16 | 2003-05-16 | Substances |
| GB0311397.4 | 2003-05-16 | ||
| GB0316356.5 | 2003-07-11 | ||
| GB0316356A GB0316356D0 (en) | 2003-07-11 | 2003-07-11 | Substances |
| CA2505558A CA2505558C (fr) | 2002-11-09 | 2003-10-30 | Presentation de recepteurs pour l'antigene des lymphocytes t |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2505558A Division CA2505558C (fr) | 2002-11-09 | 2003-10-30 | Presentation de recepteurs pour l'antigene des lymphocytes t |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2813515A1 CA2813515A1 (fr) | 2004-05-27 |
| CA2813515C true CA2813515C (fr) | 2015-12-15 |
Family
ID=43389207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2813515A Expired - Lifetime CA2813515C (fr) | 2002-11-09 | 2003-10-30 | Presentation de recepteurs pour l'antigene des lymphocytes t |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN101935636A (fr) |
| CA (1) | CA2813515C (fr) |
| DK (1) | DK2048159T3 (fr) |
| ES (1) | ES2451691T3 (fr) |
| PT (1) | PT2048159E (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201616238D0 (en) * | 2016-09-23 | 2016-11-09 | Adaptimmune Ltd | Modified T cells |
| CN112239495B (zh) * | 2020-10-29 | 2022-04-12 | 上海药明生物技术有限公司 | 稳定的tcr结构及应用 |
-
2003
- 2003-10-30 DK DK09001469.7T patent/DK2048159T3/da active
- 2003-10-30 CA CA2813515A patent/CA2813515C/fr not_active Expired - Lifetime
- 2003-10-30 CN CN2009101747961A patent/CN101935636A/zh active Pending
- 2003-10-30 ES ES09001469T patent/ES2451691T3/es not_active Expired - Lifetime
- 2003-10-30 PT PT09001469T patent/PT2048159E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101935636A (zh) | 2011-01-05 |
| ES2451691T3 (es) | 2014-03-28 |
| DK2048159T3 (da) | 2014-03-31 |
| CA2813515A1 (fr) | 2004-05-27 |
| PT2048159E (pt) | 2014-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130416 |
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| MKEX | Expiry |
Effective date: 20231030 |