CA2765058C - Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides - Google Patents

Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides Download PDF

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Publication number
CA2765058C
CA2765058C CA2765058A CA2765058A CA2765058C CA 2765058 C CA2765058 C CA 2765058C CA 2765058 A CA2765058 A CA 2765058A CA 2765058 A CA2765058 A CA 2765058A CA 2765058 C CA2765058 C CA 2765058C
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Canada
Prior art keywords
antigen
microparticles
antigens
polysaccharide
dose
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Expired - Lifetime
Application number
CA2765058A
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English (en)
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CA2765058A1 (fr
Inventor
Derek O'hagan
Manmohan Singh
Jina Kazzaz
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GlaxoSmithKline Biologicals SA
Original Assignee
Novartis Vaccines and Diagnostics Inc
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Priority claimed from CA2528007A external-priority patent/CA2528007C/fr
Publication of CA2765058A1 publication Critical patent/CA2765058A1/fr
Application granted granted Critical
Publication of CA2765058C publication Critical patent/CA2765058C/fr
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Expired - Lifetime legal-status Critical Current

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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Composition immunogène comprenant ceci : a) des microparticules polymères comportant un polymère biodégradable; b) un antigène adsorbé par les microparticules, ledit antigène étant sélectionné parmi i) un antigène anatoxine choisi parmi lanatoxine tétanique ou lanatoxine diphtérique ou ii) un antigène contenant des polysaccharides choisi parmi lantigène à polysaccharide Hib, un antigène Hib conjugué comprenant des zones polysaccharides et polypeptides, un antigène à polysaccharides méningococciques, un antigène méningococcique conjugué comprenant des zones polysaccharides et polypeptides, un antigène à polysaccharides pneumococciques et un antigène pneumococcique conjugué comprenant des zones polysaccharides et polypeptides, ou les deux; et c) un excipient acceptable sur le plan pharmaceutique et qui, de plus, comprend un autre antigène contenant des polypeptides, un autre antigène contenant des polysaccharides, un autre antigène conjugué ou un autre antigène contenant des polynucléotides, adsorbé à la surface des microparticules. Autrement, lautre antigène contenant des polypeptides, lautre antigène concernant des polysaccharides, lantigène conjugué ou lantigène contenant des polynucléotides peut être piégé dans les microparticules.
CA2765058A 2003-06-02 2004-06-02 Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides Expired - Lifetime CA2765058C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US47501003P 2003-06-02 2003-06-02
US60/475,010 2003-06-02
US51307403P 2003-10-21 2003-10-21
US60/513,074 2003-10-21
CA2528007A CA2528007C (fr) 2003-06-02 2004-06-02 Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2528007A Division CA2528007C (fr) 2003-06-02 2004-06-02 Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides

Publications (2)

Publication Number Publication Date
CA2765058A1 CA2765058A1 (fr) 2005-03-10
CA2765058C true CA2765058C (fr) 2015-09-15

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Family Applications (1)

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CA2765058A Expired - Lifetime CA2765058C (fr) 2003-06-02 2004-06-02 Compositions immunogenes basees sur des microparticules comprenant des antigenes contenant de l'anatoxine adsorbee et des polysaccharides

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CA (1) CA2765058C (fr)

Also Published As

Publication number Publication date
CA2765058A1 (fr) 2005-03-10

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