CA2705300A1 - Inhibiteurs macrocycliques de protease de l'hepatite c - Google Patents

Inhibiteurs macrocycliques de protease de l'hepatite c

Info

Publication number
CA2705300A1
CA2705300A1 CA2705300A CA2705300A CA2705300A1 CA 2705300 A1 CA2705300 A1 CA 2705300A1 CA 2705300 A CA2705300 A CA 2705300A CA 2705300 A CA2705300 A CA 2705300A CA 2705300 A1 CA2705300 A1 CA 2705300A1
Authority
CA
Canada
Prior art keywords
macrocycliques
hepatite
inhibiteurs
protease
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2705300A
Other languages
French (fr)
Inventor
Michael E. Hepperle
David Alan Campbell
David T. Winn
Juan Manuel Betancort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Xeda International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xeda International SA filed Critical Xeda International SA
Publication of CA2705300A1 publication Critical patent/CA2705300A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des composés inhibiteurs de la protéase virale de l'hépatite C, des compositions et des combinaisons comprenant les composés, des procédés de traitement d'états dans lesquels une inhibition de la protéase virale de l'hépatite C est indiquée médicalement, et des procédés de traitement d'une infection virale par l'hépatite C chez un patient humain.Hepatitis C viral protease inhibitor compounds, compositions and combinations comprising the compounds, methods of treating conditions in which hepatitis C viral protease inhibition is medically indicated, and methods of treating a viral infection with hepatitis C in a human patient.

CA2705300A 2008-02-15 2008-11-10 Inhibiteurs macrocycliques de protease de l'hepatite c Pending CA2705300A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2894108P 2008-02-15 2008-02-15
US61/028,941 2008-02-15
US8858508P 2008-08-13 2008-08-13
US61/088,585 2008-08-13
PCT/US2009/033934 WO2009102876A1 (en) 2008-02-15 2009-02-12 Macrocyclic inhibitors of hepatitis c protease

Publications (1)

Publication Number Publication Date
CA2705300A1 true CA2705300A1 (en) 2009-06-04

Family

ID=40957264

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2705300A Pending CA2705300A1 (en) 2008-02-15 2008-11-10 Inhibiteurs macrocycliques de protease de l'hepatite c

Country Status (2)

Country Link
CA (1) CA2705300A1 (en)
WO (1) WO2009102876A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105712901B (en) * 2016-01-22 2017-07-14 成都柏睿泰生物科技有限公司 A kind of synthetic method of the nonenoic acid dicyclohexyl amine salt of 2 amino of optical activity intermediate N tertbutyloxycarbonyls 8

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20023473A3 (en) * 2000-04-19 2003-01-15 Schering Corporation Macrocyclic compound and pharmaceutical preparation
US20090325889A1 (en) * 2005-08-01 2009-12-31 David Alan Campbell Hepatitis c serine protease inhibitors and uses therefor
AR061629A1 (en) * 2006-06-26 2008-09-10 Enanta Pharm Inc QUINOXALINIL MACROCICLIC INHIBITORS OF SERINE PROTEASE OF HEPATITIS VIRUS C. PROCESS OF OBTAINING AND PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
WO2009102876A1 (en) 2009-08-20

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