CA2629957C - Produits en comprimes incluant un principe actif - Google Patents
Produits en comprimes incluant un principe actif Download PDFInfo
- Publication number
- CA2629957C CA2629957C CA2629957A CA2629957A CA2629957C CA 2629957 C CA2629957 C CA 2629957C CA 2629957 A CA2629957 A CA 2629957A CA 2629957 A CA2629957 A CA 2629957A CA 2629957 C CA2629957 C CA 2629957C
- Authority
- CA
- Canada
- Prior art keywords
- coating
- product
- medicament
- caffeine
- syrup
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000576 coating method Methods 0.000 title claims abstract description 185
- 239000011248 coating agent Substances 0.000 title claims abstract description 163
- 239000003814 drug Substances 0.000 title claims abstract description 158
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 91
- 238000000034 method Methods 0.000 claims abstract description 57
- 239000000047 product Substances 0.000 claims description 141
- 239000006188 syrup Substances 0.000 claims description 52
- 235000020357 syrup Nutrition 0.000 claims description 52
- 235000009508 confectionery Nutrition 0.000 claims description 43
- 239000000796 flavoring agent Substances 0.000 claims description 34
- 235000019634 flavors Nutrition 0.000 claims description 31
- 239000000843 powder Substances 0.000 claims description 30
- 244000299461 Theobroma cacao Species 0.000 claims description 29
- 235000019219 chocolate Nutrition 0.000 claims description 28
- 239000004615 ingredient Substances 0.000 claims description 21
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- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 17
- 229960003438 aspartame Drugs 0.000 claims description 17
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 16
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 16
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- CBOQJANXLMLOSS-UHFFFAOYSA-N ethyl vanillin Chemical compound CCOC1=CC(C=O)=CC=C1O CBOQJANXLMLOSS-UHFFFAOYSA-N 0.000 claims description 6
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- 229930091371 Fructose Natural products 0.000 claims description 4
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne des procédés et des produits permettant l'administration d'un médicament ou d'un principe actif à un individu, ainsi que des procédé de production correspondants. Les produits comportent un enrobage contenant un médicament ou un principe actif. Le médicament ou le principe actif est intimement mêlé à la matière d'enrobage entourant un centre comestible. C'est en mâchant les produits que le médicament ou le principe actif se dégagent du produit à l'intérieur de la cavité buccale.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2005/041236 WO2007058645A1 (fr) | 2005-11-15 | 2005-11-15 | Produits en comprimés incluant un principe actif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2629957A1 CA2629957A1 (fr) | 2007-05-24 |
| CA2629957C true CA2629957C (fr) | 2012-07-24 |
Family
ID=36819274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2629957A Active CA2629957C (fr) | 2005-11-15 | 2005-11-15 | Produits en comprimes incluant un principe actif |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1951196A1 (fr) |
| CA (1) | CA2629957C (fr) |
| WO (1) | WO2007058645A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2934780B1 (fr) * | 2008-08-06 | 2013-01-04 | Docteur Gaetano Zannini Lab | Composition pharmaceutique sous forme de granules et procede de fabrication d'une telle composition pharmaceutique. |
| US20190022013A1 (en) | 2015-12-19 | 2019-01-24 | First Time Us Generics Llc | Soft-chew tablet pharmaceutical formulations |
| EP3389628A4 (fr) | 2015-12-19 | 2019-08-07 | Dixit, Manesh A. | Formulations pharmaceutiques de comprimés mous à mâcher |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| US6426090B1 (en) * | 1999-04-06 | 2002-07-30 | Wm. Wrigley Jr. Company | Over-coated product including tableted center and medicament |
| US20020110581A1 (en) * | 1999-04-06 | 2002-08-15 | Ream Ronald L. | Over-coated product including consumable center and medicament |
| US6322806B1 (en) * | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
-
2005
- 2005-11-15 EP EP05822314A patent/EP1951196A1/fr not_active Withdrawn
- 2005-11-15 WO PCT/US2005/041236 patent/WO2007058645A1/fr active Application Filing
- 2005-11-15 CA CA2629957A patent/CA2629957C/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2629957A1 (fr) | 2007-05-24 |
| EP1951196A1 (fr) | 2008-08-06 |
| WO2007058645A1 (fr) | 2007-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |