CA2615692A1 - Process for converting an alcohol to the corresponding fluoride - Google Patents
Process for converting an alcohol to the corresponding fluoride Download PDFInfo
- Publication number
- CA2615692A1 CA2615692A1 CA002615692A CA2615692A CA2615692A1 CA 2615692 A1 CA2615692 A1 CA 2615692A1 CA 002615692 A CA002615692 A CA 002615692A CA 2615692 A CA2615692 A CA 2615692A CA 2615692 A1 CA2615692 A1 CA 2615692A1
- Authority
- CA
- Canada
- Prior art keywords
- alcohol
- mixture
- fluoride
- molar excess
- converting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention provides a process for preparing a fluoride from its corresponding alcohol comprising the steps of (a) forming a mixture comprising (i) at least one primary or secondary alcohol and (ii) a molar excess of at least one strong, aprotic, non-nucleophilic, hindered, double bond--containing, organic base, said molar excess being less than 2 equivalents of said base per equivalent of said alcohol;
and (b) adding at least one fluorinated, saturated aliphatic or alicyclic sulfonyl fluoride to said mixture.
and (b) adding at least one fluorinated, saturated aliphatic or alicyclic sulfonyl fluoride to said mixture.
Claims
1. A process for preparing a fluoride from its corresponding alcohol comprising the steps of (a) forming a mixture comprising (i) at least one primary or secondary alcohol and (ii) a molar excess of at least one strong, aprotic, non-nucleophilic, hindered, double bond-containing, organic base, said molar excess being less than 2 equivalents of said base per equivalent of said alcohol; and (b) adding at least one fluorinated, saturated aliphatic or alicyclic sulfonyl fluoride to said mixture.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/196,512 US6248889B1 (en) | 1998-11-20 | 1998-11-20 | Process for converting an alcohol to the corresponding fluoride |
US09/196,512 | 1998-11-20 | ||
CA002349325A CA2349325C (en) | 1998-11-20 | 1999-08-19 | Process for converting an alcohol to the corresponding fluoride |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002349325A Division CA2349325C (en) | 1998-11-20 | 1999-08-19 | Process for converting an alcohol to the corresponding fluoride |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2615692A1 true CA2615692A1 (en) | 2000-06-02 |
CA2615692C CA2615692C (en) | 2010-11-30 |
Family
ID=39315318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2615692A Expired - Fee Related CA2615692C (en) | 1998-11-20 | 1999-08-19 | Process for converting an alcohol to the corresponding fluoride |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2615692C (en) |
-
1999
- 1999-08-19 CA CA2615692A patent/CA2615692C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2615692C (en) | 2010-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20130820 |