CA2614324A1 - Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer - Google Patents
Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer Download PDFInfo
- Publication number
- CA2614324A1 CA2614324A1 CA002614324A CA2614324A CA2614324A1 CA 2614324 A1 CA2614324 A1 CA 2614324A1 CA 002614324 A CA002614324 A CA 002614324A CA 2614324 A CA2614324 A CA 2614324A CA 2614324 A1 CA2614324 A1 CA 2614324A1
- Authority
- CA
- Canada
- Prior art keywords
- administering
- patient
- zosuquidar
- daunorubicin
- malignancy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229940083466 soybean lecithin Drugs 0.000 description 1
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- 210000001550 testis Anatomy 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
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- 230000002588 toxic effect Effects 0.000 description 1
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- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
- 229940029284 trichlorofluoromethane Drugs 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical class OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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Classifications
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- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69693005P | 2005-07-06 | 2005-07-06 | |
| US60/696,930 | 2005-07-06 | ||
| US11/416,571 | 2006-05-03 | ||
| US11/416,829 | 2006-05-03 | ||
| US11/416,832 | 2006-05-03 | ||
| US11/416,571 US20070010465A1 (en) | 2005-07-06 | 2006-05-03 | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
| US11/416,829 US20070010478A1 (en) | 2005-07-06 | 2006-05-03 | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
| US11/416,832 US20070010466A1 (en) | 2005-07-06 | 2006-05-03 | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
| PCT/US2006/025993 WO2007008490A2 (en) | 2005-07-06 | 2006-06-30 | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2614324A1 true CA2614324A1 (en) | 2007-01-18 |
Family
ID=37637706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002614324A Abandoned CA2614324A1 (en) | 2005-07-06 | 2006-06-30 | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1898916A4 (OSRAM) |
| JP (1) | JP2009501707A (OSRAM) |
| KR (1) | KR20080034151A (OSRAM) |
| AU (1) | AU2006269492A1 (OSRAM) |
| CA (1) | CA2614324A1 (OSRAM) |
| WO (1) | WO2007008490A2 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2923557C (en) * | 2013-09-06 | 2023-10-24 | Vanda Pharmaceuticals Inc. | Treatment of cyr61- and vegf-mediated conditions |
| CN105960239A (zh) * | 2013-11-27 | 2016-09-21 | 翁科埃斯克斯有限公司 | 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 |
| EA201990395A1 (ru) * | 2016-07-27 | 2019-07-31 | Юниверсити Оф Вирджиния Пэйтент Фаундейшн | Варианты комбинированной терапии для лечения рака |
| WO2023144830A1 (en) | 2022-01-30 | 2023-08-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Zika m protein blockers as anti-zika virus agents |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002005818A2 (en) * | 2000-07-18 | 2002-01-24 | Eli Lilly And Company | Novel method of use of multidrug resistance modulators |
-
2006
- 2006-06-30 JP JP2008520333A patent/JP2009501707A/ja active Pending
- 2006-06-30 EP EP06774465A patent/EP1898916A4/en not_active Withdrawn
- 2006-06-30 CA CA002614324A patent/CA2614324A1/en not_active Abandoned
- 2006-06-30 KR KR1020087003227A patent/KR20080034151A/ko not_active Withdrawn
- 2006-06-30 WO PCT/US2006/025993 patent/WO2007008490A2/en not_active Ceased
- 2006-06-30 AU AU2006269492A patent/AU2006269492A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007008490A2 (en) | 2007-01-18 |
| WO2007008490A3 (en) | 2008-01-10 |
| EP1898916A2 (en) | 2008-03-19 |
| AU2006269492A1 (en) | 2007-01-18 |
| EP1898916A4 (en) | 2008-10-15 |
| KR20080034151A (ko) | 2008-04-18 |
| JP2009501707A (ja) | 2009-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |