CA2581356A1 - Histone deacetylase whole cell enzyme assay - Google Patents
Histone deacetylase whole cell enzyme assay Download PDFInfo
- Publication number
- CA2581356A1 CA2581356A1 CA002581356A CA2581356A CA2581356A1 CA 2581356 A1 CA2581356 A1 CA 2581356A1 CA 002581356 A CA002581356 A CA 002581356A CA 2581356 A CA2581356 A CA 2581356A CA 2581356 A1 CA2581356 A1 CA 2581356A1
- Authority
- CA
- Canada
- Prior art keywords
- family
- protein deacetylase
- reporter molecule
- isotype
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61196404P | 2004-09-22 | 2004-09-22 | |
| US60/611,964 | 2004-09-22 | ||
| PCT/IB2005/004207 WO2007135471A1 (en) | 2004-09-22 | 2005-09-21 | Histone deacetylase whole cell enzyme assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2581356A1 true CA2581356A1 (en) | 2006-03-22 |
Family
ID=38093181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002581356A Abandoned CA2581356A1 (en) | 2004-09-22 | 2005-09-21 | Histone deacetylase whole cell enzyme assay |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060063210A1 (https=) |
| EP (1) | EP1922414A4 (https=) |
| JP (1) | JP2008532561A (https=) |
| AU (1) | AU2005336881A1 (https=) |
| CA (1) | CA2581356A1 (https=) |
| WO (1) | WO2007135471A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6897220B2 (en) * | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| US20080199897A1 (en) * | 2007-02-05 | 2008-08-21 | Methylgene Inc. | Class ii histone deacetylase whole cell enzyme assay |
| US8030344B2 (en) * | 2007-03-13 | 2011-10-04 | Methylgene Inc. | Inhibitors of histone deacetylase |
| US9636298B2 (en) | 2014-01-17 | 2017-05-02 | Methylgene Inc. | Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2093292A2 (en) * | 2000-03-24 | 2009-08-26 | Methylgene, Inc. | Inhibition of specific histone deacetylase isoforms |
-
2005
- 2005-09-21 WO PCT/IB2005/004207 patent/WO2007135471A1/en not_active Ceased
- 2005-09-21 CA CA002581356A patent/CA2581356A1/en not_active Abandoned
- 2005-09-21 EP EP05858685A patent/EP1922414A4/en not_active Withdrawn
- 2005-09-21 AU AU2005336881A patent/AU2005336881A1/en not_active Abandoned
- 2005-09-21 JP JP2008516423A patent/JP2008532561A/ja not_active Withdrawn
- 2005-09-21 US US11/231,528 patent/US20060063210A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005336881A1 (en) | 2007-05-24 |
| AU2005336881A8 (en) | 2008-08-07 |
| EP1922414A1 (en) | 2008-05-21 |
| EP1922414A4 (en) | 2008-11-05 |
| US20060063210A1 (en) | 2006-03-23 |
| WO2007135471A1 (en) | 2007-11-29 |
| JP2008532561A (ja) | 2008-08-21 |
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