CA2566815A1 - Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi - Google Patents

Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi Download PDF

Info

Publication number
CA2566815A1
CA2566815A1 CA002566815A CA2566815A CA2566815A1 CA 2566815 A1 CA2566815 A1 CA 2566815A1 CA 002566815 A CA002566815 A CA 002566815A CA 2566815 A CA2566815 A CA 2566815A CA 2566815 A1 CA2566815 A1 CA 2566815A1
Authority
CA
Canada
Prior art keywords
maldi
fac
column
deposition
deposited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002566815A
Other languages
English (en)
Inventor
William R. Davidson
Tom R. Covey
Peter Kovarik
Bori Shushan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Canada Ltd
DH Technologies Development Pte Ltd
Original Assignee
Mds Inc., Doing Business Through Its Mds Sciex Division
Applera Corporation
William R. Davidson
Tom R. Covey
Peter Kovarik
Bori Shushan
Applied Biosystems Inc.
Applied Biosystems, Llc
Applied Biosystems (Canada) Limited
Dh Technologies Development Pte. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mds Inc., Doing Business Through Its Mds Sciex Division, Applera Corporation, William R. Davidson, Tom R. Covey, Peter Kovarik, Bori Shushan, Applied Biosystems Inc., Applied Biosystems, Llc, Applied Biosystems (Canada) Limited, Dh Technologies Development Pte. Ltd. filed Critical Mds Inc., Doing Business Through Its Mds Sciex Division
Publication of CA2566815A1 publication Critical patent/CA2566815A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/728—Intermediate storage of effluent, including condensation on surface
    • G01N30/7286—Intermediate storage of effluent, including condensation on surface the store moving as a whole, e.g. moving wire
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
CA002566815A 2004-05-21 2005-05-24 Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi Abandoned CA2566815A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57300904P 2004-05-21 2004-05-21
US60/573,009 2004-05-21
PCT/CA2005/000790 WO2005114170A1 (fr) 2004-05-21 2005-05-24 Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi

Publications (1)

Publication Number Publication Date
CA2566815A1 true CA2566815A1 (fr) 2005-12-01

Family

ID=35428485

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002566815A Abandoned CA2566815A1 (fr) 2004-05-21 2005-05-24 Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi

Country Status (4)

Country Link
EP (1) EP1747456A4 (fr)
JP (1) JP2007538235A (fr)
CA (1) CA2566815A1 (fr)
WO (1) WO2005114170A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009186218A (ja) * 2008-02-04 2009-08-20 Bridgestone Corp 液体クロマトグラフ溶出液の質量スペクトル測定方法
US10481164B2 (en) 2012-03-26 2019-11-19 Amgen Inc. Method for using light scattering in real time to directly monitor and control impurity removal in purification processes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2240325A1 (fr) * 1998-03-27 1998-11-14 Synsorb Biotech, Inc. Methodes de criblage de banques de constituants
US6054047A (en) * 1998-03-27 2000-04-25 Synsorb Biotech, Inc. Apparatus for screening compound libraries
CA2318905A1 (fr) 1998-03-30 1999-10-07 Kevin B. Sparks Reseau de bragg syntonisable a periode longue et a fibre optique
US7198896B2 (en) * 1998-09-04 2007-04-03 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
US20020195555A1 (en) * 2000-10-11 2002-12-26 Weinberger Scot R. Apparatus and methods for affinity capture tandem mass spectrometry
EP1402561A4 (fr) * 2001-05-25 2007-06-06 Analytica Of Branford Inc Source d'ions maldi atmospherique et sous depression
CN1274112C (zh) * 2002-06-19 2006-09-06 华为技术有限公司 一种网管集中告警箱及其告警处理方法

Also Published As

Publication number Publication date
JP2007538235A (ja) 2007-12-27
WO2005114170A1 (fr) 2005-12-01
EP1747456A4 (fr) 2009-05-13
EP1747456A1 (fr) 2007-01-31

Similar Documents

Publication Publication Date Title
Chipuk et al. Transmission mode desorption electrospray ionization
US8648297B2 (en) Coupling of liquid chromatography with mass spectrometry by liquid sample desorption electrospray ionization (DESI)
Ramautar et al. CE–MS for proteomics: Advances in interface development and application
US20060266941A1 (en) Method and apparatus for interfacing separations techniques to MALDI-TOF mass spectrometry
Køppen et al. Determination of acidic herbicides using liquid chromatography with pneumatically assisted electrospray ionization mass spectrometric and tandem mass spectrometric detection
Foret et al. Liquid phase interfacing and miniaturization in matrix‐assisted laser desorption/ionization mass spectrometry
US7317187B2 (en) Frontal affinity chromatography/MALDI tandem mass spectrometry
Baldwin Mass spectrometers for the analysis of biomolecules
Kovarik et al. Capillary-scale frontal affinity chromatography/MALDI tandem mass spectrometry using protein-doped monolithic silica columns
Larsen et al. Mass spectrometry of biological materials
Van Veelen et al. Off-line coupling of capillary electrophoresis with matrix-assisted laser desorption mass spectrometry
Kovarik et al. Method development aspects for the quantitation of pharmaceutical compounds in human plasma with a matrix‐assisted laser desorption/ionization source in the multiple reaction monitoring mode
Pyatkivskyy et al. Coupling of ion‐molecule reactions with liquid chromatography on a quadrupole ion trap mass spectrometer
EP1550862B1 (fr) Procédé d'identification d'un analyte par électrophorèse sur gel et spectrometrie de masse
Xu et al. Online coupling techniques in ambient mass spectrometry
Iwabuchi et al. Studies on drug metabolism using liquid chromatography/mass spectrometry: Comparison of three liquid chromatographic/mass spectrometric interfaces
CA2566815A1 (fr) Chromatographie d'affinite frontale/spectrometrie de masse en tandem maldi
Govaerts et al. Hyphenation of liquid chromatography to ion trap mass spectrometry to identify minor components in polypeptide antibiotics
Orsnes et al. Interfaces for on-line liquid sample delivery for matrix-assisted laser desorption ionisation mass spectrometry
Edwards et al. Hyphenating liquid phase separation techniques with mass spectrometry: on-line or off-line
Janecki et al. A Preliminary Study of the Coupling of Desorption Electrospray Ionization—Mass Spectrometry with Pressurized Planar Electrochromatography
Shariatgorji et al. μ-Trap for the SALDI-MS screening of organic compounds prior to LC/MS analysis
Mei Matrix effects: causes and solutions
Jian Modern liquid chromatography and mass spectrometry for targeted biomarker quantitation
US20070023640A1 (en) Frontal affinity chromatography/maldi tandem mass spectrometry

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20130524