CA2560055A1 - Method of inducing or modulating immune response - Google Patents

Method of inducing or modulating immune response Download PDF

Info

Publication number
CA2560055A1
CA2560055A1 CA002560055A CA2560055A CA2560055A1 CA 2560055 A1 CA2560055 A1 CA 2560055A1 CA 002560055 A CA002560055 A CA 002560055A CA 2560055 A CA2560055 A CA 2560055A CA 2560055 A1 CA2560055 A1 CA 2560055A1
Authority
CA
Canada
Prior art keywords
axotrophin
polynucleotide
polypeptide
derived
encoded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002560055A
Other languages
English (en)
French (fr)
Inventor
Susan Marie Metcalfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACLAR Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2560055A1 publication Critical patent/CA2560055A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/53Ligases (6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA002560055A 2004-01-29 2005-01-31 Method of inducing or modulating immune response Abandoned CA2560055A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0402051.7A GB0402051D0 (en) 2004-01-29 2004-01-29 Fate determination in immunity
GB0402051.7 2004-01-29
PCT/EP2005/000934 WO2005074973A2 (en) 2004-01-29 2005-01-31 Method of inducing or modulating immune response

Publications (1)

Publication Number Publication Date
CA2560055A1 true CA2560055A1 (en) 2005-08-18

Family

ID=31971742

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002560055A Abandoned CA2560055A1 (en) 2004-01-29 2005-01-31 Method of inducing or modulating immune response

Country Status (10)

Country Link
US (2) US20070286807A1 (https=)
EP (1) EP1713495A2 (https=)
JP (1) JP2007523640A (https=)
KR (1) KR20070007291A (https=)
CN (1) CN1929855A (https=)
AU (1) AU2005210105A1 (https=)
CA (1) CA2560055A1 (https=)
GB (1) GB0402051D0 (https=)
WO (1) WO2005074973A2 (https=)
ZA (1) ZA200606331B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402051D0 (en) * 2004-01-29 2004-03-03 Metcalfe Su Fate determination in immunity
DK1826279T3 (da) * 2006-02-28 2011-09-05 Charite Universitaetsmedizin Detektering og kvalitetskontrol af regulatoriske t-celler vha. DNA-metyleringsanalyse af FoxP3--genet
GB0614536D0 (en) * 2006-07-21 2006-08-30 Metcalfe Susan M Methods of controlling cellular response to LIF
GB0721081D0 (en) * 2007-10-26 2007-12-05 Metcalfe Susan M Immuno-modulatory composition
CA2770237A1 (en) * 2009-08-05 2011-02-10 Nexigen Gmbh Human hcv-interacting proteins and methods of use
WO2014031883A1 (en) 2012-08-23 2014-02-27 Susan Marie Metcalfe Neurotherapeutic nanoparticle compositions and devices
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11779683B2 (en) * 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
CN112843222B (zh) * 2021-01-21 2023-01-31 暨南大学 Ankrd22蛋白在制备治疗或延缓自身免疫性疾病的产品中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1074617A3 (en) * 1999-07-29 2004-04-21 Research Association for Biotechnology Primers for synthesising full-length cDNA and their use
US6783969B1 (en) * 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
AU2003213606A1 (en) * 2002-03-01 2003-10-13 Exelixis, Inc. MP53s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
GB0402051D0 (en) * 2004-01-29 2004-03-03 Metcalfe Su Fate determination in immunity

Also Published As

Publication number Publication date
KR20070007291A (ko) 2007-01-15
WO2005074973A3 (en) 2005-12-08
WO2005074973A9 (en) 2006-10-26
JP2007523640A (ja) 2007-08-23
US20080125390A1 (en) 2008-05-29
US20070286807A1 (en) 2007-12-13
WO2005074973A2 (en) 2005-08-18
CN1929855A (zh) 2007-03-14
GB0402051D0 (en) 2004-03-03
AU2005210105A1 (en) 2005-08-18
ZA200606331B (en) 2007-12-27
EP1713495A2 (en) 2006-10-25

Similar Documents

Publication Publication Date Title
US20080125390A1 (en) Methods for Modulating Immune and Inflammatory Responses
Zhang et al. Tumour necrosis factor‐α (TNF‐α) transgene‐expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T‐cell activation and anti‐tumour immunity than DCs generated in recombinant TNF‐α
KR20220100913A (ko) Cd70을 표적화하는 유전자 조작된 t 세포를 사용하는 신세포 암종(rcc) 치료법
CN103930123A (zh) 可溶性介体
US20210000921A1 (en) Methods and compositions for modulating thymic function
Dalton et al. IMMUNOMONITORING OF RENAL TRANSPLANT RECIPIENTS IN THE EARLY POST-TRANSPLANT PERIOD BY SEQUENTIAL ANALYSIS OF CHEMOKINE AND CHEMOKINE RECEPTOR GENE EXPRESSION IN PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMC)
Pietrzyk et al. Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection
Fan et al. A NOVEL TOOL FOR B CELL TOLERANCE RESEARCH: CHARACTERIZATION OF MOUSE ALLOANTIBODY DEVELOPMENT USING A SIMPLE AND RELIABLE CELLULAR ELISA TECHNIQUE.
Katayama et al. PHENOTYPE AND FUNCTIONAL IDENTITY OF GM-CSF INDEPENDENT DENDRITIC CELLS GENERATED BY LONG-TERM PROPAGATION OF DC PROGENITOR CELLS IN BONE MARROW CELLS AND SKIN LANGERHANS CELLS
Zhang et al. PREVENTION OF OBLITERATIVE BRONCHIOLITIS BY JAK 3 INHIBITION WITH CP-690,550 IS ACCOMPANIED BY A DISTINCT GROWTH FACTOR GENE EXPRESSION PROFILE.
Maksymowicz et al. Recipient immature dendritic cells do not prolong allograft survival
Zhou et al. Endogenous C3 expression affects the potency of macrophages as stimulators of T cell alloreactivity
Ushigome et al. GITR activation in donor specific transfusion accelerates allograft rejection
Yang et al. The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation
Guo et al. Inducing Donor-Specific Tolerance To Islet Allografts In Diabetic Nod Mice by Posttransplant Donor Lymphocyte Infusion
Bentlejwesky et al. KINETICS OF T CELL MEMORY RECOVERY IN LUNG TRANSPLANT RECIPIENTS TREATED WITH T CELL DEPLETION THERAPIES
Yin et al. THE ROLE OF IFN-γ INDUCERS (IL-18 AND IL-12 FAMILY) IN CHRONIC ALLOGRAFTS NEPHROPATHY
Daniel et al. CIRCULATING INTERLEUKIN-10-PRODUCING DENDRITIC CELLS ARE ASSOCIATED WITH HIGH INTERFERON-γ, IL-2, AND IL-3, AND LOW IL-10 IN PLASMA OF RENAL TRANSPLANT RECIPIENTS
Azimzadeh et al. MODULATION OF IMMUNE RESPONSES TO HEART ALLOGRAFTS BY DONOR BONE MARROW INFUSION IN MONKEYS TREATED WITH CD154 COSTIMULATION BLOCKADE
Xavier et al. MIG/CXCL9 IS SIGNIFICANTLY UPREGULATED IN CULTURES OF FINE-NEEDLE ASPIRATION BIOPSY SAMPLES OF ACUTELY REJECTING KIDNEY TRANSPLANT RECIPIENTS.
Iwai et al. REGULATION OF TH1 OR TH2 CYTOKINES PRODUCED BY NKT CELLS IN CYCLOPHOSPHAMIDE (CP)-INDUCED TOLERANCE
Wyburn et al. MACROPHAGE-DERIVED INTERLEUKIN-18 IN ACUTE RAT RENAL ALLOGRAFT REJECTION.
Iwai et al. GENERATION OF NKT-DEPENDENT AND INDEPENDENT REGURATORY T CELLS IN CYCLOPHOSPHAMIDE (CP)-INDUCED TOLERANCE
Tomita et al. INSIGNIFICANT ROLE OF DONOR NKT CELLS IN THE INDUCTION AND MAINTENANCE OF CYCLOPHOSPHAMIDE (CP)-INDUCED TOLERANCE
Tokita et al. LIVER SINUSOIDAL ENDOTHELIAL CELLS ENDOCYTOSED ALLOGENEIC CELLS TOLERIZE T CELL RECOGNIZING ALLO-ANTIGENS THROUGH INDIRECT RECOGNITION BY FAS-FAS LIGAND PATHWAY.

Legal Events

Date Code Title Description
FZDE Discontinued