CA2534128C - Combinaison d'un anticholinergique et d'un steroide et leur utilisation dans le traitement de troubles respiratoires par inhalation - Google Patents
Combinaison d'un anticholinergique et d'un steroide et leur utilisation dans le traitement de troubles respiratoires par inhalation Download PDFInfo
- Publication number
- CA2534128C CA2534128C CA2534128A CA2534128A CA2534128C CA 2534128 C CA2534128 C CA 2534128C CA 2534128 A CA2534128 A CA 2534128A CA 2534128 A CA2534128 A CA 2534128A CA 2534128 C CA2534128 C CA 2534128C
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical combination
- combination according
- salt
- propellant
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne de nouvelles compositions pharmaceutiques basées sur des stéroïdes et des sels d'un anticholinergique, des procédés de préparation de celles-ci et leur utilisation dans le traitement d'affections respiratoires.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03017162.3 | 2003-07-29 | ||
EP03017162 | 2003-07-29 | ||
PCT/EP2004/008029 WO2005014005A1 (fr) | 2003-07-29 | 2004-07-17 | Combinaison d'un anticholinergique et d'un steroide et leur utilisation dans le traitement de troubles respiratoires par inhalation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2534128A1 CA2534128A1 (fr) | 2005-02-17 |
CA2534128C true CA2534128C (fr) | 2012-10-23 |
Family
ID=34130038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2534128A Expired - Lifetime CA2534128C (fr) | 2003-07-29 | 2004-07-17 | Combinaison d'un anticholinergique et d'un steroide et leur utilisation dans le traitement de troubles respiratoires par inhalation |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1651236A1 (fr) |
JP (1) | JP2007500150A (fr) |
KR (1) | KR20060052912A (fr) |
CN (1) | CN1829520A (fr) |
AU (1) | AU2004262901B2 (fr) |
BR (1) | BRPI0413054A (fr) |
CA (1) | CA2534128C (fr) |
IL (1) | IL173370A0 (fr) |
MX (1) | MXPA06001046A (fr) |
NZ (1) | NZ545443A (fr) |
RU (1) | RU2361586C2 (fr) |
WO (1) | WO2005014005A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
ES2298049B1 (es) | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
EP2100599A1 (fr) * | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques |
EP2100598A1 (fr) * | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques |
US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
SI3111927T1 (sl) | 2009-05-29 | 2020-08-31 | Pearl Therapeutics, Inc. | Sestavki za respiratorni vnos aktivnih učinkovin in s tem povezani postopki in sistemi |
EP2510928A1 (fr) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires |
JP6454323B2 (ja) | 2013-03-15 | 2019-01-16 | パール セラピューティクス,インコーポレイテッド | 粒子状結晶性材料のコンディショニングのための方法及びシステム |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (es) * | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
US20020183292A1 (en) * | 2000-10-31 | 2002-12-05 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and corticosteroids |
ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
-
2004
- 2004-07-17 AU AU2004262901A patent/AU2004262901B2/en not_active Revoked
- 2004-07-17 RU RU2006105719/15A patent/RU2361586C2/ru not_active IP Right Cessation
- 2004-07-17 CN CNA2004800220913A patent/CN1829520A/zh active Pending
- 2004-07-17 EP EP04763322A patent/EP1651236A1/fr not_active Withdrawn
- 2004-07-17 KR KR1020067001862A patent/KR20060052912A/ko not_active Application Discontinuation
- 2004-07-17 NZ NZ545443A patent/NZ545443A/en not_active IP Right Cessation
- 2004-07-17 MX MXPA06001046A patent/MXPA06001046A/es unknown
- 2004-07-17 JP JP2006521460A patent/JP2007500150A/ja active Pending
- 2004-07-17 BR BRPI0413054-5A patent/BRPI0413054A/pt not_active IP Right Cessation
- 2004-07-17 CA CA2534128A patent/CA2534128C/fr not_active Expired - Lifetime
- 2004-07-17 WO PCT/EP2004/008029 patent/WO2005014005A1/fr active Application Filing
-
2006
- 2006-01-26 IL IL173370A patent/IL173370A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2007500150A (ja) | 2007-01-11 |
MXPA06001046A (es) | 2006-04-24 |
CN1829520A (zh) | 2006-09-06 |
AU2004262901A1 (en) | 2005-02-17 |
RU2361586C2 (ru) | 2009-07-20 |
AU2004262901B2 (en) | 2010-05-13 |
IL173370A0 (en) | 2006-06-11 |
NZ545443A (en) | 2010-04-30 |
KR20060052912A (ko) | 2006-05-19 |
BRPI0413054A (pt) | 2006-10-17 |
RU2006105719A (ru) | 2007-12-10 |
EP1651236A1 (fr) | 2006-05-03 |
WO2005014005A1 (fr) | 2005-02-17 |
CA2534128A1 (fr) | 2005-02-17 |
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