CA2500252C - Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage - Google Patents

Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage Download PDF

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Publication number
CA2500252C
CA2500252C CA2500252A CA2500252A CA2500252C CA 2500252 C CA2500252 C CA 2500252C CA 2500252 A CA2500252 A CA 2500252A CA 2500252 A CA2500252 A CA 2500252A CA 2500252 C CA2500252 C CA 2500252C
Authority
CA
Canada
Prior art keywords
electrode
electrodes
droplet
mixing
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2500252A
Other languages
English (en)
Other versions
CA2500252A1 (fr
Inventor
Vamsee K. Pamula
Michael G. Pollack
Philip Y. Paik
Hong Ren
Richard B. Fair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/253,342 external-priority patent/US7329545B2/en
Priority claimed from US10/253,368 external-priority patent/US6911132B2/en
Application filed by Duke University filed Critical Duke University
Publication of CA2500252A1 publication Critical patent/CA2500252A1/fr
Application granted granted Critical
Publication of CA2500252C publication Critical patent/CA2500252C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
    • B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

L'invention concerne un appareil de manipulation de gouttelettes. Cet appareil est conçu avec une électrode à une seule face dans laquelle tous les éléments conducteurs se trouvent sur la face sur laquelle les gouttelettes sont manipulées. Il est possible de disposer d'une surface supplémentaire, parallèle à la première surface, dans le but de contenir les gouttelettes à manipuler. Les gouttelettes sont manipulées grâce à des techniques à base d'électromouillage dans lesquelles les électrodes contenues ou intégrées dans la première surface sont activées et désactivées séquentiellement par commande. L'appareil permet une certain nombre de processus de manipulations de gouttelettes, y compris la fusion et le mélange de deux gouttelettes ensemble, la division d'une gouttelette en deux ou plusieurs gouttelettes, l'échantillonnage d'un écoulement continu de liquide par formation, à partir de l'écoulement, de gouttelettes que l'on peut commander individuellement, et un mélange binaire itératif ou numérique de gouttelettes afin d'obtenir un rapport de mélange recherché.
CA2500252A 2002-09-24 2003-04-24 Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage Expired - Fee Related CA2500252C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/253,342 US7329545B2 (en) 2002-09-24 2002-09-24 Methods for sampling a liquid flow
US10/253,342 2002-09-24
US10/253,368 2002-09-24
US10/253,368 US6911132B2 (en) 2002-09-24 2002-09-24 Apparatus for manipulating droplets by electrowetting-based techniques
PCT/US2003/012754 WO2004030820A2 (fr) 2002-09-24 2003-04-24 Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage

Publications (2)

Publication Number Publication Date
CA2500252A1 CA2500252A1 (fr) 2004-04-15
CA2500252C true CA2500252C (fr) 2011-10-04

Family

ID=34681166

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2500252A Expired - Fee Related CA2500252C (fr) 2002-09-24 2003-04-24 Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage

Country Status (1)

Country Link
CA (1) CA2500252C (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013245946A1 (en) 2012-04-10 2014-11-27 Eyenovia, Inc. Spray ejector mechanisms and devices providing charge isolation and controllable droplet charge, and low dosage volume opthalmic administration
SG11201407431RA (en) 2012-05-15 2014-12-30 Eyenovia Inc Ejector devices, methods, drivers, and circuits therefor
CN114146736B (zh) * 2021-11-30 2024-02-06 上海天马微电子有限公司 微流控装置及其驱动电路和驱动方法
CN114534805A (zh) * 2022-02-09 2022-05-27 上海天马微电子有限公司 微流控装置及其驱动方法、制作方法

Also Published As

Publication number Publication date
CA2500252A1 (fr) 2004-04-15

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CA2500252C (fr) Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage

Legal Events

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Effective date: 20190424