CA2493173A1 - Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol - Google Patents

Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Download PDF

Info

Publication number
CA2493173A1
CA2493173A1 CA002493173A CA2493173A CA2493173A1 CA 2493173 A1 CA2493173 A1 CA 2493173A1 CA 002493173 A CA002493173 A CA 002493173A CA 2493173 A CA2493173 A CA 2493173A CA 2493173 A1 CA2493173 A1 CA 2493173A1
Authority
CA
Canada
Prior art keywords
dimethoxyphenyl
ethyl
piperidinemethanol
fluorophenyl
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002493173A
Other languages
English (en)
Inventor
Alan G. Bina
Edward D. Daugs
Jonathan C. Evans
Hans-Wolfram Flemming
Gerard Guillamot
Robert A. Hawthorne
Thomas H. E. Hilpert
James E. Hitt
Chi-Hsin R. King
Johannes N. Koek
Frederick M. Laskovics
John R. Lefler
Alexey L. Margolin
Sharon K. Minish
Thomas T. Ortyl
Lian G. Rajewski
Marvin J. Sack
Paul F. Skultety
Sandra K. Stolz-Dunn
Alonzo L. Tigner
Ian A. Tomlinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Aventis Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from CA002322501A external-priority patent/CA2322501C/fr
Publication of CA2493173A1 publication Critical patent/CA2493173A1/fr
Abandoned legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002493173A 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Abandoned CA2493173A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4225198A 1998-03-13 1998-03-13
US09/042,251 1998-03-13
US25071899A 1999-02-16 1999-02-16
US09/250,718 1999-02-16
CA002322501A CA2322501C (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002322501A Division CA2322501C (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Publications (1)

Publication Number Publication Date
CA2493173A1 true CA2493173A1 (fr) 1999-09-16

Family

ID=34279252

Family Applications (4)

Application Number Title Priority Date Filing Date
CA002493546A Abandoned CA2493546A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
CA002492600A Abandoned CA2492600A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1- [2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
CA002493173A Abandoned CA2493173A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
CA002493559A Abandoned CA2493559A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CA002493546A Abandoned CA2493546A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
CA002492600A Abandoned CA2492600A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1- [2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002493559A Abandoned CA2493559A1 (fr) 1998-03-13 1999-03-11 Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Country Status (1)

Country Link
CA (4) CA2493546A1 (fr)

Also Published As

Publication number Publication date
CA2493559A1 (fr) 1999-09-16
CA2493546A1 (fr) 1999-09-16
CA2492600A1 (fr) 1999-09-16

Similar Documents

Publication Publication Date Title
US5606065A (en) Process for preparing N-alkylene piperidino compounds and their enantiomers
JP2010143925A (ja) （Ｒ）−α−（２，３−ジメトキシフェニル）−１−［２−（４−フルオロフェニル）エチル］−４−ピペリジンメタノールの製造方法
US20090227798A1 (en) Novel processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
US20070265450A1 (en) Novel processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
EP1091938A2 (fr) Derives de piperidine a action antihistaminique et intermediaires pour l'elaboration de ces derives
US6673933B2 (en) Antihistaminic piperidine derivatives and intermediates for the preparation thereof
CA2493173A1 (fr) Procedes de preparation de (r)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
NZ523652A (en) 4-(2,3-dimethoxybenzoyl)-pyridine or 4-((2,3-dimethoxyphenyl)-4-pyridine
MXPA00008938A (en) PROCESSES FOR THE PREPARATION OF (R)-&agr;- (2,3-DIMETHOXYPHENYL)- 1-[2-(4- FLUOROPHENYL)ETHYL]- 4-PIPERIDINEMETHANOL
AU2007200674C1 (en) Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
CA2491932A1 (fr) Derives de piperidine a action antihistaminique et intermediaires pour l'elaboration de ces derives

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20100107