CA2492538A1 - Ensemble de soupape pour dispositifs microfluidiques et procede pour ouvrir et fermer cet ensemble - Google Patents

Ensemble de soupape pour dispositifs microfluidiques et procede pour ouvrir et fermer cet ensemble Download PDF

Info

Publication number
CA2492538A1
CA2492538A1 CA002492538A CA2492538A CA2492538A1 CA 2492538 A1 CA2492538 A1 CA 2492538A1 CA 002492538 A CA002492538 A CA 002492538A CA 2492538 A CA2492538 A CA 2492538A CA 2492538 A1 CA2492538 A1 CA 2492538A1
Authority
CA
Canada
Prior art keywords
elastically deformable
deformer
recess
valve assembly
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002492538A
Other languages
English (en)
Inventor
Dennis E. Mead
Zbigniew T. Bryning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Priority claimed from US10/403,652 external-priority patent/US7135147B2/en
Priority claimed from US10/403,640 external-priority patent/US7201881B2/en
Priority claimed from US10/426,587 external-priority patent/US6817373B2/en
Application filed by Individual filed Critical Individual
Publication of CA2492538A1 publication Critical patent/CA2492538A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0026—Valves using channel deformation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K2099/0069—Bistable microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Micromachines (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

La présente invention concerne un ensemble de soupape de manipulation fluidique (20) normalement ouverte, un système correspondant et un procédé pour fermer, rouvrir et refermer ledit ensemble. Ledit ensemble de soupape de manipulation fluidique normalement ouverte peut comprendre un substrat (22) présentant une première surface, avec des premiers et seconds évidements (28, 30) formés dans cette première surface. Un canal en retrait (34) peut être ménagé dans la première surface. Ce canal en retrait peut s'étendre du premier évidement au second évidement et peut être au moins partiellement défini par un premier matériau déformable (42) qui présente un premier module d'élasticité. L'ensemble de soupape selon cette invention peut également comprendre un matériau à déformation élastique (32), qui présente un module d'élasticité supérieur au module d'élasticité du premier matériau déformable, ainsi qu'une couche adhésive (44), qui est en contact avec la première surface.
CA002492538A 2002-07-26 2003-07-23 Ensemble de soupape pour dispositifs microfluidiques et procede pour ouvrir et fermer cet ensemble Abandoned CA2492538A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US39885102P 2002-07-26 2002-07-26
US39894602P 2002-07-26 2002-07-26
US60/398,946 2002-07-26
US60/398,851 2002-07-26
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/336,274 2003-01-03
US10/336,706 2003-01-03
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/403,640 2003-03-31
US10/403,652 US7135147B2 (en) 2002-07-26 2003-03-31 Closing blade for deformable valve in a microfluidic device and method
US10/403,652 2003-03-31
US10/403,640 US7201881B2 (en) 2002-07-26 2003-03-31 Actuator for deformable valves in a microfluidic device, and method
US10/426,587 US6817373B2 (en) 2002-07-26 2003-04-30 One-directional microball valve for a microfluidic device
US10/426,587 2003-04-30
PCT/US2003/022897 WO2004011149A1 (fr) 2002-07-26 2003-07-23 Ensemble de soupape pour dispositifs microfluidiques et procede pour ouvrir et fermer cet ensemble

Publications (1)

Publication Number Publication Date
CA2492538A1 true CA2492538A1 (fr) 2004-02-05

Family

ID=31192577

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002492538A Abandoned CA2492538A1 (fr) 2002-07-26 2003-07-23 Ensemble de soupape pour dispositifs microfluidiques et procede pour ouvrir et fermer cet ensemble

Country Status (5)

Country Link
EP (1) EP1534433A4 (fr)
JP (1) JP4290696B2 (fr)
AU (1) AU2003254105B2 (fr)
CA (1) CA2492538A1 (fr)
WO (1) WO2004011149A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
JP4743487B2 (ja) * 2005-05-25 2011-08-10 日立アロカメディカル株式会社 マイクロチップにおける流体流れ制御装置及び方法
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
WO2007108773A1 (fr) * 2006-03-23 2007-09-27 Agengy For Science, Technology And Research Dispositif d'analyse de l'état d'une particule
JP5484909B2 (ja) * 2006-12-14 2014-05-07 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 液体の吸入又は操作のための器具
US9283562B2 (en) 2008-06-26 2016-03-15 Fujikura Kasei Co., Ltd. Liquid channel device and production method therefor
CN103341370B (zh) * 2008-10-28 2015-04-29 藤仓化成株式会社 液体流道装置及其制作方法
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
FR2966368B1 (fr) 2010-10-22 2014-02-28 Biomerieux Sa Procede pour isoler un puits a echantillon d'une carte test pour analyse et carte test obtenue
BR112013027990B1 (pt) 2011-05-18 2020-11-03 Diasorin S.P.A. estrutura de válvulas em um dispositivo de processamento de amostras e método para funcionamento de válvulas em um dispositivo de processamento de amostras
ES2870874T3 (es) 2011-05-18 2021-10-27 Diasorin S P A Sistemas y métodos para detectar la presencia de un volumen seleccionado de material en un dispositivo de procesamiento de muestra
MX336625B (es) 2011-05-18 2016-01-26 3M Innovative Properties Co Sistemas y metodos para medicion volumetrica en dispositivo de procesamiento de muestra.
US9322054B2 (en) * 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154888A (en) * 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
US5254479A (en) * 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
US5290518A (en) * 1992-08-17 1994-03-01 Eastman Kodak Company Flexible extraction device with burstable sidewall
US5288463A (en) * 1992-10-23 1994-02-22 Eastman Kodak Company Positive flow control in an unvented container
US6001307A (en) 1996-04-26 1999-12-14 Kyoto Daiichi Kagaku Co., Ltd. Device for analyzing a sample
US6426230B1 (en) * 1997-08-01 2002-07-30 Qualigen, Inc. Disposable diagnostic device and method
GB9804483D0 (en) 1998-03-02 1998-04-29 Central Research Lab Ltd Apparatus for and method of controlling the rate of flow of fluid along a pathway
CA2412061A1 (fr) * 2000-06-20 2001-12-27 Kawamura Institute Of Chemical Research Microdispositif a structure multicouche et son procede de fabrication
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
WO2002024320A1 (fr) * 2000-09-22 2002-03-28 Kawamura Institute Of Chemical Research Tres petit dispositif chimique et procede de reglage du debit de celui-ci
US7056475B2 (en) * 2002-01-30 2006-06-06 Agilent Technologies, Inc. Fluidically isolated pumping and metered fluid delivery system and methods
GB0203662D0 (en) * 2002-02-15 2002-04-03 Syrris Ltd A microreactor

Also Published As

Publication number Publication date
AU2003254105B2 (en) 2006-05-04
WO2004011149A1 (fr) 2004-02-05
EP1534433A1 (fr) 2005-06-01
JP4290696B2 (ja) 2009-07-08
EP1534433A4 (fr) 2009-01-07
JP2005535859A (ja) 2005-11-24
AU2003254105A1 (en) 2004-02-16

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued