CA2485433A1 - Preparation of non-crystalline and crystalline dihydrate forms of azithromycin - Google Patents

Preparation of non-crystalline and crystalline dihydrate forms of azithromycin Download PDF

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Publication number
CA2485433A1
CA2485433A1 CA002485433A CA2485433A CA2485433A1 CA 2485433 A1 CA2485433 A1 CA 2485433A1 CA 002485433 A CA002485433 A CA 002485433A CA 2485433 A CA2485433 A CA 2485433A CA 2485433 A1 CA2485433 A1 CA 2485433A1
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CA
Canada
Prior art keywords
crystalline
preparation
azithromycin
dihydrate forms
forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002485433A
Other languages
French (fr)
Other versions
CA2485433C (en
Inventor
Miguel Santos Bayod Jasanada
Isidro Llorente Garcia
Felix Fernandez Mari
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AsturPharma SA
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Individual
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Filing date
Publication date
Priority claimed from ES009902620A external-priority patent/ES2177373B1/en
Application filed by Individual filed Critical Individual
Publication of CA2485433A1 publication Critical patent/CA2485433A1/en
Application granted granted Critical
Publication of CA2485433C publication Critical patent/CA2485433C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention describes new procedures for the preparation of the macrolide azithromycin in its non-crystalline and crystalline dihydrate forms, which are characterized and clearly differentiated by means of the following methods and techniques:
1. IR Spectroscopy.
2. Differential Scan Calorimetry (DSC).
3. X-Ray Diffraction.
4. Hygroscopicity.
5. Crystallinity test (Light Polarized Microscopy)
CA002485433A 1999-11-26 2000-11-24 Preparation of non-crystalline and crystalline dihydrate forms of azithromycin Expired - Fee Related CA2485433C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009902620A ES2177373B1 (en) 1999-11-26 1999-11-26 PREPARATION OF AZITHROMYCIN IN ITS NON-CRYSTALLINE FORM
ES9902620 1999-11-26
CA002326930A CA2326930C (en) 1999-11-26 2000-11-24 Preparation of non-crystalline and crystalline dihydrate forms of azithromycin

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002326930A Division CA2326930C (en) 1999-11-26 2000-11-24 Preparation of non-crystalline and crystalline dihydrate forms of azithromycin

Publications (2)

Publication Number Publication Date
CA2485433A1 true CA2485433A1 (en) 2001-05-26
CA2485433C CA2485433C (en) 2008-01-29

Family

ID=34081389

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002485433A Expired - Fee Related CA2485433C (en) 1999-11-26 2000-11-24 Preparation of non-crystalline and crystalline dihydrate forms of azithromycin

Country Status (1)

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CA (1) CA2485433C (en)

Also Published As

Publication number Publication date
CA2485433C (en) 2008-01-29

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