CA2467542A1 - Amides d'acide 1h-pyrrolo[3,2-b]pyridine-3-carboxylique - Google Patents
Amides d'acide 1h-pyrrolo[3,2-b]pyridine-3-carboxylique Download PDFInfo
- Publication number
- CA2467542A1 CA2467542A1 CA002467542A CA2467542A CA2467542A1 CA 2467542 A1 CA2467542 A1 CA 2467542A1 CA 002467542 A CA002467542 A CA 002467542A CA 2467542 A CA2467542 A CA 2467542A CA 2467542 A1 CA2467542 A1 CA 2467542A1
- Authority
- CA
- Canada
- Prior art keywords
- c6alkyl
- alkoxy
- pyrrolo
- pyridine
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
L'invention concerne des amides d'acide 1H-pyrrolo[3,2-b]pyridine-3-carboxylique qui se lient au site benzodiazépine de récepteurs GABA¿A?. De tels composés peuvent être utilisés pour moduler la liaison de ligands à des récepteurs GABA¿A? in vivo et in vitro et sont particulièrement utiles dans le traitement de divers troubles du système nerveux central chez l'homme, les animaux de compagnie domestiqués et le bétail.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33302701P | 2001-11-19 | 2001-11-19 | |
US60/333,027 | 2001-11-19 | ||
PCT/US2002/037157 WO2003044018A1 (fr) | 2001-11-19 | 2002-11-19 | Amides d'acide 1h-pyrrolo[3,2-b]pyridine-3-carboxylique |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2467542A1 true CA2467542A1 (fr) | 2003-05-30 |
Family
ID=23300941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002467542A Abandoned CA2467542A1 (fr) | 2001-11-19 | 2002-11-19 | Amides d'acide 1h-pyrrolo[3,2-b]pyridine-3-carboxylique |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1453831A1 (fr) |
JP (1) | JP2005516901A (fr) |
AU (1) | AU2002366092A1 (fr) |
BR (1) | BR0214301A (fr) |
CA (1) | CA2467542A1 (fr) |
MX (1) | MXPA04004711A (fr) |
WO (1) | WO2003044018A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2865208B1 (fr) * | 2004-01-16 | 2009-01-16 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo[3.2.1]octanecarboxmique, leur preparation et leur application en therapeutique |
FR2890072A1 (fr) | 2005-09-01 | 2007-03-02 | Fournier S A Sa Lab | Nouveaux composesde pyrrolopyridine |
US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
BR112015030399B8 (pt) | 2013-06-05 | 2023-01-10 | C&C Res Lab | Derivados heterocíclicos, uso dos referidos derivados e composição farmacêutica para a prevenção ou tratamento de doenças associadas com a ativação da proteína stat3 |
GB201317363D0 (en) | 2013-10-01 | 2013-11-13 | Eisai Ltd | Novel compounds |
WO2023082044A1 (fr) * | 2021-11-09 | 2023-05-19 | 暨南大学 | Composé amide hétérocyclique de 5-formyle et son utilisation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750702A (en) * | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
-
2002
- 2002-11-19 MX MXPA04004711A patent/MXPA04004711A/es active IP Right Grant
- 2002-11-19 WO PCT/US2002/037157 patent/WO2003044018A1/fr active Application Filing
- 2002-11-19 CA CA002467542A patent/CA2467542A1/fr not_active Abandoned
- 2002-11-19 EP EP02803679A patent/EP1453831A1/fr not_active Withdrawn
- 2002-11-19 JP JP2003545655A patent/JP2005516901A/ja active Pending
- 2002-11-19 AU AU2002366092A patent/AU2002366092A1/en not_active Abandoned
- 2002-11-19 BR BR0214301-1A patent/BR0214301A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1453831A1 (fr) | 2004-09-08 |
MXPA04004711A (es) | 2005-08-16 |
BR0214301A (pt) | 2004-10-13 |
WO2003044018A1 (fr) | 2003-05-30 |
JP2005516901A (ja) | 2005-06-09 |
AU2002366092A1 (en) | 2003-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20111121 |