CA2453655A1 - Nouveaux canaux a porte protonique humains - Google Patents

Nouveaux canaux a porte protonique humains Download PDF

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Publication number
CA2453655A1
CA2453655A1 CA002453655A CA2453655A CA2453655A1 CA 2453655 A1 CA2453655 A1 CA 2453655A1 CA 002453655 A CA002453655 A CA 002453655A CA 2453655 A CA2453655 A CA 2453655A CA 2453655 A1 CA2453655 A1 CA 2453655A1
Authority
CA
Canada
Prior art keywords
hasic1b
hasic1
protein
sequence
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002453655A
Other languages
English (en)
Inventor
Kazimierz Babinski
Stefano Catarsi
Philippe Seguela
Naima Abbadi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002352702A external-priority patent/CA2352702A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002453655A priority Critical patent/CA2453655A1/fr
Publication of CA2453655A1 publication Critical patent/CA2453655A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un nouveau canal ionique à porte protonique humain (hASIC1B) et des polynucléotides qui identifient et codent hASIC1B; des vecteurs d'expression issus du génie génétique et des cellules hôtes comprenant les séquences d'acides nucléiques codant hASIC1B ainsi qu'un procédé de production de hASIC1B. Cette invention concerne également l'utilisation de hASIC1B, ainsi que des agonistes, des anticorps ou des antagonistes se liant spécifiquement à hASIC1B, dans la prévention et le traitement des maladies associées à l'expression de hASIC1B. De plus, cette invention porte sur l'utilisation de molécules antisens destinées à des polynucléotides codant hASIC1B pour le traitement de maladies associées à l'expression de hASIC1B. Cette invention concerne également des dosages de diagnostic, dans lesquels on utilise lesdits polynucléotides, ou des fragments ou les compléments de ces derniers, et des anticorps se liant de manière spécifique à hASIC1B.
CA002453655A 2001-07-18 2002-07-18 Nouveaux canaux a porte protonique humains Abandoned CA2453655A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002453655A CA2453655A1 (fr) 2001-07-18 2002-07-18 Nouveaux canaux a porte protonique humains

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002352702A CA2352702A1 (fr) 2001-07-18 2001-07-18 Nouveau canal ionique humain sensible aux protons (asic)
CA2,352,702 2001-07-18
CA002453655A CA2453655A1 (fr) 2001-07-18 2002-07-18 Nouveaux canaux a porte protonique humains
PCT/CA2002/001120 WO2003008448A2 (fr) 2001-07-18 2002-07-18 Nouveaux canaux a porte protonique humains

Publications (1)

Publication Number Publication Date
CA2453655A1 true CA2453655A1 (fr) 2003-01-30

Family

ID=32094415

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002453655A Abandoned CA2453655A1 (fr) 2001-07-18 2002-07-18 Nouveaux canaux a porte protonique humains

Country Status (1)

Country Link
CA (1) CA2453655A1 (fr)

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued