CA2446437A1 - Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation - Google Patents

Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation Download PDF

Info

Publication number
CA2446437A1
CA2446437A1 CA002446437A CA2446437A CA2446437A1 CA 2446437 A1 CA2446437 A1 CA 2446437A1 CA 002446437 A CA002446437 A CA 002446437A CA 2446437 A CA2446437 A CA 2446437A CA 2446437 A1 CA2446437 A1 CA 2446437A1
Authority
CA
Canada
Prior art keywords
novx
polypeptide
nucleic acid
protein
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002446437A
Other languages
English (en)
Inventor
John P. Ii Alsobrook
David W. Anderson
Ferenc L. Boldog
Catherine E. Burgess
Stacie J. Casman
Andrei Chapoval
Schlomit Edinger
Valerie Gerlach
Linda Gorman
Erik Gunther
Xiaojia Guo
Ramesh Kekuda
Denise M. Lepley
Li Li
Xiaohong Liu
Uriel M. Malyankar
Charles E. Miller
Isabelle Millet
Muralidhara Padigaru
Meera Patturajan
Carol E. A. Pena
Daniel K. Rieger
Suresh G. Shenoy
Richard A. Shimkets
Kimberly A. Spytek
Raymond J. Taupier, Jr.
Corine A. M. Vernet
Edward Z. Voss
Bryan D. Zerhusen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/138,588 external-priority patent/US20040018594A1/en
Application filed by Individual filed Critical Individual
Publication of CA2446437A1 publication Critical patent/CA2446437A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)

Abstract

Cette invention concerne des séquences d'acides nucléiques qui codent des polypeptides. L'invention concerne également des anticorps qui se lient de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments desdits polypeptide, polynucléotide et anticorps. L'invention concerne en outre des procédés thérapeutiques, diagnostiques et de recherche servant au diagnostic, au traitement et à la prévention de troubles dans lesquels interviennent un des nouveaux acides nucléiques, polypeptides ou anticorps humains, ou des fragments de ceux-ci.
CA002446437A 2001-05-03 2002-05-02 Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation Abandoned CA2446437A1 (fr)

Applications Claiming Priority (55)

Application Number Priority Date Filing Date Title
US28839501P 2001-05-03 2001-05-03
US60/288,395 2001-05-03
US28890001P 2001-05-04 2001-05-04
US60/288,900 2001-05-04
US28908701P 2001-05-07 2001-05-07
US60/289,087 2001-05-07
US29075301P 2001-05-14 2001-05-14
US60/290,753 2001-05-14
US29118901P 2001-05-15 2001-05-15
US60/291,189 2001-05-15
US29124301P 2001-05-16 2001-05-16
US60/291,243 2001-05-16
US29200101P 2001-05-18 2001-05-18
US60/292,001 2001-05-18
US29237401P 2001-05-21 2001-05-21
US60/292,374 2001-05-21
US29258701P 2001-05-22 2001-05-22
US60/292,587 2001-05-22
US29310701P 2001-05-23 2001-05-23
US60/293,107 2001-05-23
US29411001P 2001-05-29 2001-05-29
US60/294,110 2001-05-29
US29443401P 2001-05-30 2001-05-30
US60/294,434 2001-05-30
US29482701P 2001-05-31 2001-05-31
US60/294,827 2001-05-31
US29898801P 2001-06-18 2001-06-18
US60/298,988 2001-06-18
US30890101P 2001-07-31 2001-07-31
US60/308,901 2001-07-31
US31338801P 2001-08-17 2001-08-17
US60/313,388 2001-08-17
US31385101P 2001-08-21 2001-08-21
US31393701P 2001-08-21 2001-08-21
US60/313,937 2001-08-21
US60/313,851 2001-08-21
US32270101P 2001-09-17 2001-09-17
US32280201P 2001-09-17 2001-09-17
US60/322,802 2001-09-17
US60,322,701 2001-09-17
US32475701P 2001-09-25 2001-09-25
US60/324,757 2001-09-25
US32531401P 2001-09-27 2001-09-27
US32568201P 2001-09-27 2001-09-27
US60/325,682 2001-09-27
US60/325,314 2001-09-27
US33212901P 2001-11-21 2001-11-21
US60/332,129 2001-11-21
US33688201P 2001-12-03 2001-12-03
US60/336,882 2001-12-03
US34030501P 2001-12-14 2001-12-14
US60/340,305 2001-12-14
US10/138,588 2002-05-01
US10/138,588 US20040018594A1 (en) 2001-05-03 2002-05-01 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
PCT/US2002/014342 WO2002090504A2 (fr) 2001-05-03 2002-05-02 Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation

Publications (1)

Publication Number Publication Date
CA2446437A1 true CA2446437A1 (fr) 2002-11-14

Family

ID=27586816

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002446437A Abandoned CA2446437A1 (fr) 2001-05-03 2002-05-02 Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation

Country Status (4)

Country Link
EP (1) EP1463747A2 (fr)
JP (1) JP2005506054A (fr)
CA (1) CA2446437A1 (fr)
WO (1) WO2002090504A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1104462B1 (fr) 1998-08-10 2007-01-03 Agensys, Inc. Bpc-1: proteine secretee, specifique du cerveau, exprimee et secretee par des cellules cancereuses de la prostate et de la vessie
EP1666492A1 (fr) * 2000-06-02 2006-06-07 Genentech, Inc. Polypeptides sécrétés et transmembranaires ainsi que les acides nucléiques codant pour ceux-ci
US7157558B2 (en) 2001-06-01 2007-01-02 Genentech, Inc. Polypeptide encoded by a polynucleotide overexpresses in tumors
EP1404807A4 (fr) * 2001-06-06 2005-03-23 Human Genome Sciences 20 proteines humaines secretees
US7141381B2 (en) 2002-04-25 2006-11-28 Bristol-Myers Squibb Company Human leucine-rich repeat-containing proteins specifically expressed in the nervous system
US20130030007A1 (en) * 2010-01-07 2013-01-31 Akron Molecules Gmbh Obesity Small Molecules
EP3668891B1 (fr) * 2017-08-16 2023-07-26 Lgv1 S.R.L. Isoform vtft d'une proteine bpifb4 destinee aux maladies neuronales et aux blessures

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006839A1 (fr) * 1996-07-15 1998-02-19 Human Genome Sciences, Inc. Proteine de type cd44
US6368794B1 (en) * 1999-01-15 2002-04-09 Incyte Genomics, Inc. Detection of altered expression of genes regulating cell proliferation

Also Published As

Publication number Publication date
EP1463747A2 (fr) 2004-10-06
WO2002090504A3 (fr) 2004-08-12
JP2005506054A (ja) 2005-03-03
WO2002090504A2 (fr) 2002-11-14

Similar Documents

Publication Publication Date Title
US20060063200A1 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US20050287564A1 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US20030185815A1 (en) Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
CA2448073A1 (fr) Polypeptides therapeutiques, acides nucleiques codant ces polypeptides et procedes d'utilisation
CA2446437A1 (fr) Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant les antigenes, et procedes d'utilisation
US20030236188A1 (en) Novel human proteins, polynucleotides encoding them and methods of using the same
CA2448540A1 (fr) Polypeptides therapeutiques, acides nucleiques codant ces polypeptides, et leurs procedes d'utilisation
CA2442729A1 (fr) Polypeptides therapeutiques, acides nucleiques les codant, et procedes d'utilisation
US20040018594A1 (en) Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
WO2002081629A2 (fr) Nouvelles proteines humaines, polynucleotides codant celles-ci et procede d'utilisation de ceux-ci
US20040029790A1 (en) Novel human proteins, polynucleotides encoding them and methods of using the same
US20030068618A1 (en) Novel proteins and nucleic acids encoding same
US20030059775A1 (en) Novel proteins and nucleic acids encoding same
WO2002072770A2 (fr) Nouvelles proteines humaines, polynucleotides codant pour celles-ci et methodes d'utilisation de celles-ci
US20030235821A1 (en) Novel Human proteins, polynucleotides encoding them and methods of using the same
EP1661998A2 (fr) Polypeptides antigéniques, anticorps s'y liant, acides nucléiques codant pour les antigènes, et méthodes pour leur utilisation
WO2002072771A2 (fr) Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant pour les antigenes et procedes d'utilisation
US20060210559A1 (en) Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
US20030195149A1 (en) Endozepine-like proteins, polynucleotides encoding them and methods of using the same
US20030207801A1 (en) Novel polypeptides and nucleic acids encoding same
AU2002303959A1 (en) Novel human proteins, polynucleotides encoding them and methods of using the same
AU2002312258A1 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AU2002314770A1 (en) Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
WO2002006342A2 (fr) Nouvelles proteines et acides nucleiques les codant
AU2002309498A1 (en) Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use

Legal Events

Date Code Title Description
FZDE Dead