CA2434320A1 - Chimiokines utilisees comme adjuvants de la reponse immunitaire - Google Patents
Chimiokines utilisees comme adjuvants de la reponse immunitaire Download PDFInfo
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- CA2434320A1 CA2434320A1 CA002434320A CA2434320A CA2434320A1 CA 2434320 A1 CA2434320 A1 CA 2434320A1 CA 002434320 A CA002434320 A CA 002434320A CA 2434320 A CA2434320 A CA 2434320A CA 2434320 A1 CA2434320 A1 CA 2434320A1
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Abstract
Selon la présente invention, les cellules dendritiques jouent un rôle déterminant dans les réponses immunitaires spécifiques aux antigènes. Cette invention concerne des substances et des méthodes destinées à traiter des états pathologiques, tels que le cancer et les maladies auto-immunes, en favorisant ou en inhibant la migration ou l'activation de cellules dendritiques de présentation antigénique. Plus particulièrement, on utilise des chimiokines pour induire, amplifier ou moduler une réponse immunitaire. Dans un mode de réalisation, ces chimiokines sont utilisées pour attirer des cellules dendritiques vers le site d'administration d'antigènes. Un nombre accru de cellules dendritiques au niveau du site d'administration d'antigènes indique une augmentation de l'absorption antigénique et une modification de la réponse immunitaire.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/768,917 US7217700B2 (en) | 1998-07-16 | 2001-01-24 | Chemokines as adjuvants of immune response |
| US09/768,917 | 2001-01-24 | ||
| PCT/US2002/001849 WO2002058723A2 (fr) | 2001-01-24 | 2002-01-22 | Chimiokines utilisees comme adjuvants de la reponse immunitaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2434320A1 true CA2434320A1 (fr) | 2002-08-01 |
Family
ID=25083870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002434320A Abandoned CA2434320A1 (fr) | 2001-01-24 | 2002-01-22 | Chimiokines utilisees comme adjuvants de la reponse immunitaire |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1392351A2 (fr) |
| JP (2) | JP2004520043A (fr) |
| CA (1) | CA2434320A1 (fr) |
| MX (1) | MXPA03006587A (fr) |
| WO (1) | WO2002058723A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005046748A1 (fr) * | 2003-11-12 | 2005-05-26 | James Keenan | Dispositif et procede pour attirer des cellules malades et des substances etrangeres |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030077247A1 (en) * | 2001-09-20 | 2003-04-24 | Schering Corporation | Chemokines as adjuvants of immune response |
| WO2003035106A1 (fr) * | 2001-10-24 | 2003-05-01 | Chemocentryx | Procedes et compositions servant a induire une reponse immune |
| EP1599572A4 (fr) * | 2003-02-14 | 2007-06-13 | Univ Southern California | Compositions et methodes pour immunotherapie anticancereuse |
| US20040191215A1 (en) * | 2003-03-25 | 2004-09-30 | Michael Froix | Compositions for induction of a therapeutic response |
| CN100342017C (zh) * | 2004-05-10 | 2007-10-10 | 中国医学科学院肿瘤医院肿瘤研究所 | 基因重组趋化抗原疫苗 |
| EP2347774B1 (fr) | 2005-12-13 | 2017-07-26 | The President and Fellows of Harvard College | Echafaudages pour transplantation cellulaire |
| WO2009002401A2 (fr) | 2007-06-21 | 2008-12-31 | President And Fellows Of Harvard College | Échafaudages pour recueil ou élimination de cellules |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| US10328133B2 (en) | 2008-02-13 | 2019-06-25 | President And Fellows Of Harvard College | Continuous cell programming devices |
| WO2011014871A1 (fr) * | 2009-07-31 | 2011-02-03 | President And Fellows Of Harvard College | Programmation de cellules à des fins de thérapie tolérogénique |
| JP6104806B2 (ja) | 2010-10-06 | 2017-03-29 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル |
| US10045947B2 (en) | 2011-04-28 | 2018-08-14 | President And Fellows Of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| US9486512B2 (en) | 2011-06-03 | 2016-11-08 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
| EP2838515B1 (fr) | 2012-04-16 | 2019-11-20 | President and Fellows of Harvard College | Compositions de silice mésoporeuse pour moduler les réponses immunitaires |
| JP7348708B2 (ja) | 2014-04-30 | 2023-09-21 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 組み合わせワクチン装置および癌細胞を殺滅する方法 |
| EP3250250A4 (fr) | 2015-01-30 | 2019-05-22 | President and Fellows of Harvard College | Matériaux péritumoraux et intratumoraux pour traitement anticancéreux |
| JP7094533B2 (ja) | 2015-04-10 | 2022-07-04 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫細胞捕捉デバイスおよびその製造および使用方法 |
| JP7138864B2 (ja) | 2016-02-06 | 2022-09-20 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫を再構成するための造血ニッチの再現 |
| US10980877B2 (en) * | 2016-04-28 | 2021-04-20 | The University Of Chicago | Method for treating melanoma using lymphangiogenesis inducers and a melanoma-specific antigen |
| CN109789092A (zh) | 2016-07-13 | 2019-05-21 | 哈佛学院院长等 | 抗原呈递细胞模拟支架及其制备和使用方法 |
| US11419928B2 (en) | 2017-10-25 | 2022-08-23 | The Johns Hopkins University | Methods and compositions for treating cancer |
| WO2019094938A2 (fr) | 2017-11-13 | 2019-05-16 | The University Of Chicago | Méthodes et compositions pour le traitement des plaies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562347B1 (en) * | 1998-03-12 | 2003-05-13 | The United States Of America As Represented By The Department Of Health And Human Services | Chemokine-tumor antigen fusion proteins as cancer vaccines |
| EP0974357A1 (fr) * | 1998-07-16 | 2000-01-26 | Schering-Plough | Chemokines comme adjuvants de la réponse immunitaire |
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2002
- 2002-01-22 CA CA002434320A patent/CA2434320A1/fr not_active Abandoned
- 2002-01-22 WO PCT/US2002/001849 patent/WO2002058723A2/fr active Application Filing
- 2002-01-22 MX MXPA03006587A patent/MXPA03006587A/es not_active Application Discontinuation
- 2002-01-22 EP EP02705895A patent/EP1392351A2/fr not_active Withdrawn
- 2002-01-22 JP JP2002559057A patent/JP2004520043A/ja active Pending
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- 2008-02-04 JP JP2008024609A patent/JP2008133296A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005046748A1 (fr) * | 2003-11-12 | 2005-05-26 | James Keenan | Dispositif et procede pour attirer des cellules malades et des substances etrangeres |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008133296A (ja) | 2008-06-12 |
| EP1392351A2 (fr) | 2004-03-03 |
| WO2002058723A2 (fr) | 2002-08-01 |
| MXPA03006587A (es) | 2003-09-22 |
| JP2004520043A (ja) | 2004-07-08 |
| WO2002058723A3 (fr) | 2003-12-18 |
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