CA2427594A1 - Process for s-aryl-cysteine and derivatives - Google Patents

Process for s-aryl-cysteine and derivatives Download PDF

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Publication number
CA2427594A1
CA2427594A1 CA002427594A CA2427594A CA2427594A1 CA 2427594 A1 CA2427594 A1 CA 2427594A1 CA 002427594 A CA002427594 A CA 002427594A CA 2427594 A CA2427594 A CA 2427594A CA 2427594 A1 CA2427594 A1 CA 2427594A1
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CA
Canada
Prior art keywords
aryl
cysteine
derivatives
preparing
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002427594A
Other languages
French (fr)
Other versions
CA2427594C (en
Inventor
Jack D. Brown
Richard R. Dauer
Peter John Harrington
Dave A. Johnston
Hiralal N. Khatri
Gary K. Rowe
Robert J. Topping
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
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Individual
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Filing date
Publication date
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Priority claimed from CA002276318A external-priority patent/CA2276318C/en
Publication of CA2427594A1 publication Critical patent/CA2427594A1/en
Application granted granted Critical
Publication of CA2427594C publication Critical patent/CA2427594C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention provides methods for preparing S-aryl cysteines in enantiomeric excess of greater than about 96%. Specifically, the present invention provides enantioselective methods for preparing S-aryl cysteines starting from cystine, cysteine or a serine.
CA002427594A 1998-06-29 1999-06-28 Process for s-aryl-cysteine and derivatives Expired - Fee Related CA2427594C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9110298P 1998-06-29 1998-06-29
US60/091,102 1998-06-29
US9614298P 1998-08-11 1998-08-11
US60/096,142 1998-08-11
CA002276318A CA2276318C (en) 1998-06-29 1999-06-28 Process for s-aryl-cysteine and derivatives

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002276318A Division CA2276318C (en) 1998-06-29 1999-06-28 Process for s-aryl-cysteine and derivatives

Publications (2)

Publication Number Publication Date
CA2427594A1 true CA2427594A1 (en) 1999-12-29
CA2427594C CA2427594C (en) 2007-09-04

Family

ID=38474415

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002427594A Expired - Fee Related CA2427594C (en) 1998-06-29 1999-06-28 Process for s-aryl-cysteine and derivatives

Country Status (1)

Country Link
CA (1) CA2427594C (en)

Also Published As

Publication number Publication date
CA2427594C (en) 2007-09-04

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Effective date: 20180628