CA2426324A1 - A restraining assembly for use with a magnetic resonance imaging device - Google Patents
A restraining assembly for use with a magnetic resonance imaging device Download PDFInfo
- Publication number
- CA2426324A1 CA2426324A1 CA002426324A CA2426324A CA2426324A1 CA 2426324 A1 CA2426324 A1 CA 2426324A1 CA 002426324 A CA002426324 A CA 002426324A CA 2426324 A CA2426324 A CA 2426324A CA 2426324 A1 CA2426324 A1 CA 2426324A1
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- restrainer
- core module
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- 238000002595 magnetic resonance imaging Methods 0.000 title claims abstract 14
- 230000000452 restraining effect Effects 0.000 title claims 22
- 239000000837 restrainer Substances 0.000 claims abstract 27
- 241001465754 Metazoa Species 0.000 claims abstract 22
- 238000000034 method Methods 0.000 claims abstract 15
- 230000009977 dual effect Effects 0.000 claims abstract 8
- 239000003990 capacitor Substances 0.000 claims 9
- 230000005540 biological transmission Effects 0.000 claims 4
- 238000013016 damping Methods 0.000 claims 4
- 230000002452 interceptive effect Effects 0.000 claims 3
- 239000004677 Nylon Substances 0.000 claims 2
- 239000004809 Teflon Substances 0.000 claims 2
- 229920006362 Teflon® Polymers 0.000 claims 2
- 229920001778 nylon Polymers 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 239000003989 dielectric material Substances 0.000 claims 1
- 230000005284 excitation Effects 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000002610 neuroimaging Methods 0.000 claims 1
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 claims 1
- 238000006213 oxygenation reaction Methods 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/341—Constructional details, e.g. resonators, specially adapted to MR comprising surface coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/70—Means for positioning the patient in relation to the detecting, measuring or recording means
- A61B5/702—Posture restraints
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/34046—Volume type coils, e.g. bird-cage coils; Quadrature bird-cage coils; Circularly polarised coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/34007—Manufacture of RF coils, e.g. using printed circuit board technology; additional hardware for providing mechanical support to the RF coil assembly or to part thereof, e.g. a support for moving the coil assembly relative to the remainder of the MR system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/345—Constructional details, e.g. resonators, specially adapted to MR of waveguide type
- G01R33/3453—Transverse electromagnetic [TEM] coils
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
The present invention relates to system and methods of performing magnetic resonance imaging (MRI) in awake animals. The invention utilizes head and body restrainers to position an awake animal relative to a radio frequency dual coil system operating in a high field magnetic resonance imaging system to provide images of high resolution without motion artifact.
Claims (50)
1. A restraining assembly for an awake animal within a magnetic resonance imaging (MRI) device comprising:
a head restrainer that restrains a head of the awake animal;
a body restrainer that holds a body of the awake animal;
a support frame positioned in a cavity of the MRI device, the support frame carrying the head restrainer and the body restrainer; and a volume coil mounted on the support frame, the volume coil extending around the body restrainer such that the assembly can be inserted in the MRI device.
a head restrainer that restrains a head of the awake animal;
a body restrainer that holds a body of the awake animal;
a support frame positioned in a cavity of the MRI device, the support frame carrying the head restrainer and the body restrainer; and a volume coil mounted on the support frame, the volume coil extending around the body restrainer such that the assembly can be inserted in the MRI device.
2. The restraining assembly Claim 1 wherein the head retainer comprises:
a head holder having a channel that receives and restrains the head, the head holder having a surface coil within the volume coil;
a position tube carried by the support mount that retains the head holder, the head holder having an aperture extending from the channel to communicate with an aperture in the position tube, a bite bar within the aperture and a plurality of adjustable components to secure an animal's head.
a head holder having a channel that receives and restrains the head, the head holder having a surface coil within the volume coil;
a position tube carried by the support mount that retains the head holder, the head holder having an aperture extending from the channel to communicate with an aperture in the position tube, a bite bar within the aperture and a plurality of adjustable components to secure an animal's head.
3. The restraining assembly of Claim 2 wherein the body restrainer comprises:
an elongated body tube carried by the mounting unit; and a shoulder positioning device carried by the elongated body tube that positions the shoulders of the animal.
an elongated body tube carried by the mounting unit; and a shoulder positioning device carried by the elongated body tube that positions the shoulders of the animal.
4. The restraining assembly of Claim 1 wherein the frame comprises:
a front mounting plate having an access hole extending through the plate, the front mounting plate adapted to be secured into the bore of the MRI
device;
a rear mounting plate parallel and spaced from the front mounting plate and having an access hole extending through the plate, the rear mounting plate adapted to be secured into the bore of the MRI device; and a plurality of support rods extending between the mounting plates to space and support the mounting plates in relative position, the support rods including a damping structure for reducing transmission of movement of the body restrainer to the head retainer.
a front mounting plate having an access hole extending through the plate, the front mounting plate adapted to be secured into the bore of the MRI
device;
a rear mounting plate parallel and spaced from the front mounting plate and having an access hole extending through the plate, the rear mounting plate adapted to be secured into the bore of the MRI device; and a plurality of support rods extending between the mounting plates to space and support the mounting plates in relative position, the support rods including a damping structure for reducing transmission of movement of the body restrainer to the head retainer.
5. The restraining assembly of Claim 4 wherein the damping structure of the frame further comprises gaskets interposed between the support rods and the mounting plates for reducing transmission of movement of the body restrainer to the head restrainer.
6. The restraining assembly of Claim 4 wherein the damping structure further comprising a gasket interposed between the front mounting plate and the position tube of the head restrainer for reducing transmission of movement of the body restrainer to the head restrainer.
7. The restraining assembly of Claim 1 wherein the assembly is non-magnetic and immobilizes an awake animal for insertion into a bore of a magnetic resonance imaging (MRI) device comprising:
a support frame adapted to be slidably mounted in the bore of the MRI device, the frame including;
a front mounting plate having an access hole extending through the plate;
a rear mounting plate parallel and spaced from the front mounting plate; and a plurality of support rods extending between fine mounting plates to space and support the mounting plates in relative position;
a body restrainer for holding the body of the awake animal, the body restrainer including:
an elongated body tube carried by the frame; and a shoulder restrainer carried by the elongated body tube; and a head restrainer for immobilizing the head of the awake animal, the head retainer including:
a head holder having an opening to receive and restrain the head of an animal, the head holder receiving an RF coil in the opening; and a position tube carried by the frame for retaining the head holder, the head holder having an aperture extending from the opening to communicate with an aperture in the position tube.
a support frame adapted to be slidably mounted in the bore of the MRI device, the frame including;
a front mounting plate having an access hole extending through the plate;
a rear mounting plate parallel and spaced from the front mounting plate; and a plurality of support rods extending between fine mounting plates to space and support the mounting plates in relative position;
a body restrainer for holding the body of the awake animal, the body restrainer including:
an elongated body tube carried by the frame; and a shoulder restrainer carried by the elongated body tube; and a head restrainer for immobilizing the head of the awake animal, the head retainer including:
a head holder having an opening to receive and restrain the head of an animal, the head holder receiving an RF coil in the opening; and a position tube carried by the frame for retaining the head holder, the head holder having an aperture extending from the opening to communicate with an aperture in the position tube.
8. The restraining system o~ Claim 7 further comprising a volume coil to generate an excitation RF signal, the volume coil having a cylindrical non-magnetic core module having an outer shield and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis and defining an inner surface, a plurality of bores extending parallel to, and spaced from, the longitudinal axis, each bore receiving one of the support rods for laterally movement of the volume coil relative to the head restrainer.
9. The restraining system of Claim 8 wherein the head holder further comprises a pair of lateral ear clamping screws extending horizontally through the sides of the head holder into the bore of the aperture and perpendicular to the axis and above a horizontal bite bar to abut and limit the horizontal movement of the animal.
10. The restraining system of Claim 9 wherein the head holder further comprises a nose clamping screw extending inward through the top of the head holder into the bore of the aperture that abuts the nose of an animal above the bite bar and secure the animal's jaw thereon.
11. The restraining system of Claim 9 wherein the head holder further comprises a pair of jaw anchor screws extending inward through the head holder into the bore of the aperture and a head clamping screw located at the top of the head holder and extending inward through the head holder into the bore of the aperture.
12. The restraining system of Claim 9 further comprising a restraining jacket that restrains the body of the animal.
13. The restraining system of Claim 12 wherein the head holder further comprises a nose clamping screw extending inward through the top of the head holder into the bore of the aperture and adapted to abut the nose of an animal above the bite bar and secure the animal's jaw thereon.
14. The restraining system of Claim 13 wherein the head holder further comprises a pair of jaw anchor screws extending inward through the head holder into the bore of the aperture.
15. The restraining system of Claim 14 further comprising ear pads wherein the ear pads are placed under the protective ear piece.
16. The restraining system of Claim 15 wherein the head holder further comprises a head clamping screw located at the top of the head holder and extending inward through the head holder into the bore of the aperture.
17. The restraining system of Claim 8 further comprising an RF surface coil for detecting the MRI signal, the RF surface coil carried by the head holder.
18. The restraining system of Claim 17 wherein the volume coil further comprises:
a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module;
a pair of circuit boards carried by the ends surfaces of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface;
a resonating element having strip lines, a shielding strip, and at least one tuneable, variable capacitor;
a detuning circuit carried on the circuit board for detuning the resonating element; and a RF decoupling circuit carried on the circuit boards for reducing interference between a DC detuning signal and an RF signal.
a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module;
a pair of circuit boards carried by the ends surfaces of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface;
a resonating element having strip lines, a shielding strip, and at least one tuneable, variable capacitor;
a detuning circuit carried on the circuit board for detuning the resonating element; and a RF decoupling circuit carried on the circuit boards for reducing interference between a DC detuning signal and an RF signal.
19. The retraining system of Claim 18 further comprising a transceiver unit having a RF transmitter and a RF receiver, the transceiver unit connected to the surface coil and the volume coil.
20. A volume coil for a magnetic resonance system, the volume coil comprising:
a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis and defining an inner surface, a plurality of condictive strip lines extending parallel to and spaced from the longitudinal axis;
a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module;
a pair of circuit boards carried by the ends of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface of the core module;
a resonating element having strip lines, shielding strips and at least one tuneable capacitor;
a detuning circuit carried a circuit board for detuning the resonating element; and a RF decoupling circuit carried a circuit board for reducing interference between a DC detuning signal and a RF signal.
a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis and defining an inner surface, a plurality of condictive strip lines extending parallel to and spaced from the longitudinal axis;
a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module;
a pair of circuit boards carried by the ends of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface of the core module;
a resonating element having strip lines, shielding strips and at least one tuneable capacitor;
a detuning circuit carried a circuit board for detuning the resonating element; and a RF decoupling circuit carried a circuit board for reducing interference between a DC detuning signal and a RF signal.
21. The volume coil of Claim 20 wherein the core module is formed of Teflon, nylon or GR-10.
22. The volume coil of Claim 20 wherein the strip lines are electroplated on the core module.
23. The volume coil of Claim 20 wherein the adjacent shielding strips are coupled by at least one capacitor attaches adjacent shielding strips at alternative ends of the shielding strips.
24. The volume coil of Claim 23 further comprising:
a matching circuit for adjusting the impedance of the resonating elements to that of the RF source; and a filter for separating the high frequency RF signal from interfering the DC detuning signal.
a matching circuit for adjusting the impedance of the resonating elements to that of the RF source; and a filter for separating the high frequency RF signal from interfering the DC detuning signal.
25. The volume coil of Claim 24 wherein the detuning circuit has a pair of pin diodes.
26. The volume coil of Claim 24 wherein the RF decoupling circuit has a plurality of high frequency inductors.
27. A dual coil system for magnetic resonance imaging, the system comprising:
a surface coil; and a volume coil having a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis.
a surface coil; and a volume coil having a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis.
28. The dual coil system of Claim 27 further comprising a transceiver unit having a RF transmitter and a RF receiver, the transceiver unit connected to the surface coil and the volume coil.
29. The dual coil system of Claim 28 wherein the volume coil defines an inner surface; a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module; a pair of circuit boards carried at the ends of the core module; and a plurality of resonating elements, each of the resonating elements including one of the strip lines and at least one tuneable capacitor, the volume coil further comprising a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface of the core module and wherein the adjacent shielding strips are connected by at least one capacitor attaching adjacent shielding strips at alternative ends of the shielding strips.
30. The dual coil system of Claim 29 wherein the core module of the volume coil is formed of a dielectric material and the strip lines of the volume coil are electroplated on the core module.
31. The dual coil system of Claim 30 further comprising a matching circuit for adjusting the impedance of the resonating elements to that of the RF source and a filter for separating the high frequency RF signal from interfering with the DC tuning/detuning signal.
32. The dual coil system of Claim 30 wherein both the surface coil and volume coil have a detuning circuit for detuning the resonating element and a RF
decoupling circuit for reducing interference between a DC detuning signal and a RF signal.
decoupling circuit for reducing interference between a DC detuning signal and a RF signal.
33. The dual coil system of Claim 30 wherein the surface coil comprises a single loop or a dome shaped coil having a curvilinear surface.
34. A surface coil comprising;
support surface having an inner surface and an outer surface;
a circuit board assembly;
at least a pair of conductive strips attached the support surface;
a circuit connecting the conductive strips; and a tuneable circuit element.
support surface having an inner surface and an outer surface;
a circuit board assembly;
at least a pair of conductive strips attached the support surface;
a circuit connecting the conductive strips; and a tuneable circuit element.
35. The surface coil of Claim 34 wherein the circuit comprises at least one capacitor, the tunable element comprises a variable capacitor and there are at least four conductive strips carried on the concave inner surface and further comprising a resonating element including one of the conductive strips on the concave inner surface, and a shielding strip on the convex outer surface.
36. The surface coil of Claim 35 further comprising:
a detuning circuit for detuning the resonating elements;
a RF decoupling circuit for reducing interference between a DC
detuning signal and an RF signal; and a matching circuit for adjusting the impedance of the resonating elements to that of a RF source.
a detuning circuit for detuning the resonating elements;
a RF decoupling circuit for reducing interference between a DC
detuning signal and an RF signal; and a matching circuit for adjusting the impedance of the resonating elements to that of a RF source.
37. A method of performing neuroimaging on awake animals comprising:
providing a restraining assembly including a head restrainer, a body restrainer; and a support frame slidably mounted in a bore of the MRI device, the frame carrying both the head restrainer and the body restrainer, and having a damping structure for reducing transmission of movement of the body restrainer to the head retainer;
restraining a head of an animal in the head restrainer;
attaching the head restrainer to the frame;
inserting the body of the animal in the body restrainer;
attaching the body restrainer to the frame; and performing a magnetic resonance imaging measurement on an un-anesthetized animal.
providing a restraining assembly including a head restrainer, a body restrainer; and a support frame slidably mounted in a bore of the MRI device, the frame carrying both the head restrainer and the body restrainer, and having a damping structure for reducing transmission of movement of the body restrainer to the head retainer;
restraining a head of an animal in the head restrainer;
attaching the head restrainer to the frame;
inserting the body of the animal in the body restrainer;
attaching the body restrainer to the frame; and performing a magnetic resonance imaging measurement on an un-anesthetized animal.
38. The method of Claim 37 further comprising amplifying the sensitivity of low field strength magnets by implementing exogenous contrast agents, blood oxygenation-level-dependant contrast and pulse sequences.
39. The method of Claim 38 further comprising creating a three dimensional digital map of the imaged brain.
40. The method of Claim 37 wherein a volume coil transmits the RF signal and a surface coil that receives the RF response from the animal.
41. The method of Claim 37 further comprising providing a transceiver unit having a RF transmitter and a RF receiver, the transceiver unit connected to the surface coil and the volume coil.
42. The method of Claim 37 further comprising providing a system including:
a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis and defining an inner surface, a plurality of condictive strip lines extending parallel to the longitudinal axis; and a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module.
a cylindrical non-magnetic core module having an outer surface and a longitudinal axis, a cylindrical bore extending through the core module along the longitudinal axis and defining an inner surface, a plurality of condictive strip lines extending parallel to the longitudinal axis; and a plurality of conductive strip lines, the strip lines extending parallel to the longitudinal axis on the inner surface of the core module.
43. The method of Claim 42 further comprising providing:
a pair of circuit boards carried by the ends of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface of the core module; and a resonating element having strip lines, shielding strips and at least one tuneable capacitor.
a pair of circuit boards carried by the ends of the core module;
a plurality of shielding strips extending parallel to the longitudinal axis on the outer surface of the core module; and a resonating element having strip lines, shielding strips and at least one tuneable capacitor.
44. The method of Claim 43 further comprising providing a detuning circuit on a circuit board for detuning the resonating element; and a RF decoupling circuit carried a circuit board for reducing interference between a DC detuning signal and a RF signal.
45. The method of Claim 42 wherein the core module is formed of Teflon, nylon or GR-10.
46. The method of Claim 42 wherein the strip lines are electroplated on the core module.
47. The method of Claim 43 wherein adjacent shielding strips are coupled by at least one capacitor attaches adjacent shielding strips at alternative ends of the shielding strips.
48. The method of Claim 43 further comprising:
a matching circuit for adjusting the impedance of resonating elements to that of the RF source; and a filter for separating the high frequency RF signal from interfering the DC detuning signal.
a matching circuit for adjusting the impedance of resonating elements to that of the RF source; and a filter for separating the high frequency RF signal from interfering the DC detuning signal.
49. The method of Claim 44 wherein the detuning circuit has a pair of pin diodes.
50. The method of Claim 44 wherein the RF decoupling circuit has a plurality of high frequency inductors.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/694,087 | 2000-10-20 | ||
| US09/694,087 US6711430B1 (en) | 1998-10-09 | 2000-10-20 | Method and apparatus for performing neuroimaging |
| PCT/US2001/032586 WO2002032306A2 (en) | 2000-10-20 | 2001-10-18 | Method and apparatus for performing neuroimaging |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2426324A1 true CA2426324A1 (en) | 2002-04-25 |
| CA2426324C CA2426324C (en) | 2010-09-21 |
Family
ID=24787348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2426324A Expired - Fee Related CA2426324C (en) | 2000-10-20 | 2001-10-18 | A restraining assembly for use with a magnetic resonance imaging device |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1326532A2 (en) |
| AU (1) | AU2002213396A1 (en) |
| CA (1) | CA2426324C (en) |
| WO (1) | WO2002032306A2 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7133713B2 (en) * | 2002-10-10 | 2006-11-07 | Visualsonics Inc. | Integrated multi-rail imaging system |
| US8078256B2 (en) | 2002-10-10 | 2011-12-13 | Visualsonics Inc. | Integrated multi-rail imaging system |
| US7084630B2 (en) | 2004-01-28 | 2006-08-01 | Worcester Polytechnic Institute | Multi-modal RF coil for magnetic resonance imaging |
| CA2645229A1 (en) | 2006-03-09 | 2007-09-13 | Insight Neuroimaging Systems, Llc | Microstrip coil designs for mri devices |
| US7378848B2 (en) * | 2006-05-05 | 2008-05-27 | M2M Imaging Corp. | Magnetic resonance coil system |
| WO2009015678A1 (en) | 2007-08-01 | 2009-02-05 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Sample holding device, in particular for holding a rodent or an mr phantom in an mrt device |
| US9320453B2 (en) | 2011-05-06 | 2016-04-26 | Rapid Biomedical Gmbh | Assembly to perform imaging on rodents |
| CN113100780B (en) * | 2021-03-04 | 2022-07-26 | 北京大学 | Automatic processing method for synchronous brain electricity-function magnetic resonance data |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4751464A (en) * | 1987-05-04 | 1988-06-14 | Advanced Nmr Systems, Inc. | Cavity resonator with improved magnetic field uniformity for high frequency operation and reduced dielectric heating in NMR imaging devices |
| US5400787A (en) * | 1993-11-24 | 1995-03-28 | Magna-Lab, Inc. | Inflatable magnetic resonance imaging sensing coil assembly positioning and retaining device and method for using the same |
| DE4408195C2 (en) * | 1994-03-11 | 1996-09-05 | Bruker Analytische Messtechnik | Magnetic resonance resonator |
| US5646530A (en) * | 1995-09-19 | 1997-07-08 | Diagnostic Instruments, Inc. | Surface coil for high resolution imaging using a magnetic resonance imaging apparatus |
| DE19616464A1 (en) * | 1996-04-25 | 1997-11-06 | Philips Patentverwaltung | MR device with a solenoid arrangement and a surface coil arrangement |
| JP3532446B2 (en) * | 1999-03-31 | 2004-05-31 | 株式会社日立メディコ | MRI body probe and MRI apparatus |
-
2001
- 2001-10-18 AU AU2002213396A patent/AU2002213396A1/en not_active Abandoned
- 2001-10-18 CA CA2426324A patent/CA2426324C/en not_active Expired - Fee Related
- 2001-10-18 WO PCT/US2001/032586 patent/WO2002032306A2/en active Application Filing
- 2001-10-18 EP EP01981776A patent/EP1326532A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2426324C (en) | 2010-09-21 |
| AU2002213396A1 (en) | 2002-04-29 |
| EP1326532A2 (en) | 2003-07-16 |
| WO2002032306A3 (en) | 2003-02-06 |
| WO2002032306A2 (en) | 2002-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20131018 |