CA2422837A1 - Appareils et procedes pour le fractionnement en continu de particules a l'aide de forces acoustiques et autres forces - Google Patents

Appareils et procedes pour le fractionnement en continu de particules a l'aide de forces acoustiques et autres forces Download PDF

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Publication number
CA2422837A1
CA2422837A1 CA 2422837 CA2422837A CA2422837A1 CA 2422837 A1 CA2422837 A1 CA 2422837A1 CA 2422837 CA2422837 CA 2422837 CA 2422837 A CA2422837 A CA 2422837A CA 2422837 A1 CA2422837 A1 CA 2422837A1
Authority
CA
Canada
Prior art keywords
chamber
carrier medium
matter
acoustic
electrical signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2422837
Other languages
English (en)
Inventor
Xiao-Bo Wang
Jing Cheng
Lei Wu
Junquan Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aviva Biosciences Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 00130562 external-priority patent/CN1221309C/zh
Priority claimed from US09/679,023 external-priority patent/US6881314B1/en
Application filed by Individual filed Critical Individual
Publication of CA2422837A1 publication Critical patent/CA2422837A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/0005—Field flow fractionation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3678—Separation of cells using wave pressure; Manipulation of individual corpuscles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/0005—Field flow fractionation
    • G01N2030/004—Field flow fractionation characterised by opposing force
    • G01N2030/0055—Field flow fractionation characterised by opposing force hyperlayer, i.e. different particle populations in hyperlayers elevated above wall
    • G01N2030/006—Field flow fractionation characterised by opposing force hyperlayer, i.e. different particle populations in hyperlayers elevated above wall lift hyperlayer, i.e. hydrodynamic lift forces dominate steric effect
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/0005—Field flow fractionation
    • G01N2030/004—Field flow fractionation characterised by opposing force
    • G01N2030/0065—Dielectric FFF, i.e. opposing forces dominate hydrodynamic lift forces and steric effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)

Abstract

Cette invention concerne le domaine du fractionnement en continu, et notamment des appareils et procédés de discrimination des matières par utilisation d'une force acoustique ou d'une force acoustique alliée à une force électrophorétique ou diélectrophorétique, en fractionnement continu.
CA 2422837 2000-09-30 2001-09-20 Appareils et procedes pour le fractionnement en continu de particules a l'aide de forces acoustiques et autres forces Abandoned CA2422837A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN 00130562 CN1221309C (zh) 2000-09-30 2000-09-30 利用声场力和其它作用力对微粒进行场流分离的装置和方法
CN00130562.X 2000-09-30
US09/679,023 2000-10-04
US09/679,023 US6881314B1 (en) 2000-09-30 2000-10-04 Apparatuses and methods for field flow fractionation of particles using acoustic and other forces
PCT/US2001/042280 WO2002029400A2 (fr) 2000-09-30 2001-09-20 Appareils et procedes pour le fractionnement en continu de particules a l'aide de forces acoustiques et autres forces

Publications (1)

Publication Number Publication Date
CA2422837A1 true CA2422837A1 (fr) 2002-04-11

Family

ID=25739617

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2422837 Abandoned CA2422837A1 (fr) 2000-09-30 2001-09-20 Appareils et procedes pour le fractionnement en continu de particules a l'aide de forces acoustiques et autres forces

Country Status (4)

Country Link
EP (1) EP1322953A2 (fr)
AU (1) AU2002213426A1 (fr)
CA (1) CA2422837A1 (fr)
WO (1) WO2002029400A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100494360C (zh) 2001-03-22 2009-06-03 博奥生物有限公司 细胞分离方法及其应用
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
EP1627675A4 (fr) * 2003-12-17 2012-12-12 Panasonic Corp Dispositif de separation de composants, procede de production de ce dispositif et procede de separation de composants utilisant ce dispositif
SE528313C2 (sv) 2004-09-24 2006-10-17 Spectronic Ab Metod och apparat för separering av partiklar med hjälp av ultraljudvågor
JP4835047B2 (ja) * 2005-06-24 2011-12-14 富士ゼロックス株式会社 微粒子分散液の製造方法
EP1915211B1 (fr) * 2005-07-07 2009-09-16 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Procede et dispositif de manipulation acoustique de particules, cellules et virus
EP2041299A4 (fr) 2006-07-14 2010-01-13 Aviva Biosciences Corp Procedes et compositions servant a detecter des cellules rares dans un echantillon biologique
CN102016543B (zh) 2008-04-25 2013-04-10 新日铁住金株式会社 金属材料中微粒的粒度分布测定方法
KR20130094181A (ko) * 2010-04-15 2013-08-23 지＆엠 노르덴 에이비 가스 검출방법 및 그 가스 검출기
GB201010724D0 (en) * 2010-06-25 2010-08-11 Isis Innovation Acoustic separators
US9731062B2 (en) 2011-08-29 2017-08-15 The Charles Stark Draper Laboratory, Inc. System and method for blood separation by microfluidic acoustic focusing
FR2979256B1 (fr) * 2011-08-30 2014-09-26 Centre Nat Rech Scient Dispositif de manipulation d'objets par champs de force acoustique
US9504780B2 (en) 2013-01-30 2016-11-29 The Charles Stark Draper Laboratory, Inc. Extracorporeal clearance of organophosphates from blood on an acoustic separation device
WO2014138739A1 (fr) * 2013-03-08 2014-09-12 The Charles Stark Draper Laboratory, Inc. Système et procédé pour séparation du sang par focalisation acoustique microfluidique
US10946133B2 (en) 2014-07-31 2021-03-16 The Charles Stark Draper Laboratory, Inc. Systems and methods for parallel channel microfluidic separation
US10099002B2 (en) 2014-07-31 2018-10-16 The Charles Stark Draper Laboratory, Inc. Systems and methods for parallel channel microfluidic separation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449938A (en) * 1967-08-03 1969-06-17 Univ Utah Method for separating and detecting fluid materials
US4743361A (en) * 1983-10-31 1988-05-10 Internationale Octrooi Maatschappij "Octropa" Bv Manipulation of particles
GB8427546D0 (en) * 1984-10-31 1984-12-05 Unilever Plc Processing
GB8612759D0 (en) * 1986-05-27 1986-07-02 Unilever Plc Manipulating particulate matter
AT389235B (de) * 1987-05-19 1989-11-10 Stuckart Wolfgang Verfahren zur reinigung von fluessigkeiten mittels ultraschall und vorrichtungen zur durchfuehrung dieses verfahrens
GB8718756D0 (en) * 1987-08-07 1987-09-16 Unilever Plc Supporting means
US5192450A (en) * 1990-12-17 1993-03-09 The United States Of America As Represented By The Administrator Of The United States National Aeronautics And Space Administration Acoustophoresis separation method
US5993630A (en) * 1996-01-31 1999-11-30 Board Of Regents The University Of Texas System Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation
US5811658A (en) * 1997-04-29 1998-09-22 Medtronic, Inc. Ultrasonic diversion of microair in blood

Also Published As

Publication number Publication date
WO2002029400A3 (fr) 2003-04-17
EP1322953A2 (fr) 2003-07-02
WO2002029400A2 (fr) 2002-04-11
AU2002213426A1 (en) 2002-04-15

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Legal Events

Date Code Title Description
FZDE Discontinued