CA2413037A1 - Intermediates for producing antitumor indolopyrrolocarbazole derivatives - Google Patents

Intermediates for producing antitumor indolopyrrolocarbazole derivatives Download PDF

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Publication number
CA2413037A1
CA2413037A1 CA002413037A CA2413037A CA2413037A1 CA 2413037 A1 CA2413037 A1 CA 2413037A1 CA 002413037 A CA002413037 A CA 002413037A CA 2413037 A CA2413037 A CA 2413037A CA 2413037 A1 CA2413037 A1 CA 2413037A1
Authority
CA
Canada
Prior art keywords
intermediates
formula
indolopyrrolocarbazole derivatives
producing
producing antitumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002413037A
Other languages
French (fr)
Other versions
CA2413037C (en
Inventor
Katsuhisa Kojiri
Hisao Kondo
Hiroharu Arakawa
Mitsuru Ohkubo
Hiroyuki Suda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Pharmaceutical Co., Ltd.
Katsuhisa Kojiri
Hisao Kondo
Hiroharu Arakawa
Mitsuru Ohkubo
Hiroyuki Suda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharmaceutical Co., Ltd., Katsuhisa Kojiri, Hisao Kondo, Hiroharu Arakawa, Mitsuru Ohkubo, Hiroyuki Suda filed Critical Banyu Pharmaceutical Co., Ltd.
Priority claimed from CA002190007A external-priority patent/CA2190007C/en
Publication of CA2413037A1 publication Critical patent/CA2413037A1/en
Application granted granted Critical
Publication of CA2413037C publication Critical patent/CA2413037C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Disclosed are intermediates including those of the formula:

(see formula I) (in which R4 is H, alkyl, benzyloxymethyl or aralkyl; R5 and R6 are each OH; R7 to R10 are OH-protecting group; and R11 is H or amino-protecting group), useful for producing indolopyrrolocarbazole derivatives of the formula:

(see formula I) that inhibit tumor cell growth.
CA002413037A 1994-05-09 1995-05-02 Intermediates for producing antitumor indolopyrrolocarbazole derivatives Expired - Fee Related CA2413037C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP119483/1994 1994-05-09
JP11948394 1994-05-09
JP145648/1994 1994-06-03
JP14564894 1994-06-03
CA002190007A CA2190007C (en) 1994-05-09 1995-05-02 Antitumor indolopyrrolocarbazole derivatives

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002190007A Division CA2190007C (en) 1994-05-09 1995-05-02 Antitumor indolopyrrolocarbazole derivatives

Publications (2)

Publication Number Publication Date
CA2413037A1 true CA2413037A1 (en) 1995-11-16
CA2413037C CA2413037C (en) 2007-06-26

Family

ID=27170222

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413037A Expired - Fee Related CA2413037C (en) 1994-05-09 1995-05-02 Intermediates for producing antitumor indolopyrrolocarbazole derivatives

Country Status (1)

Country Link
CA (1) CA2413037C (en)

Also Published As

Publication number Publication date
CA2413037C (en) 2007-06-26

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