CA2412375A1 - Systeme informatique permettant la modelisation de l'expression d'une proteine dans un organe - Google Patents

Systeme informatique permettant la modelisation de l'expression d'une proteine dans un organe Download PDF

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Publication number
CA2412375A1
CA2412375A1 CA002412375A CA2412375A CA2412375A1 CA 2412375 A1 CA2412375 A1 CA 2412375A1 CA 002412375 A CA002412375 A CA 002412375A CA 2412375 A CA2412375 A CA 2412375A CA 2412375 A1 CA2412375 A1 CA 2412375A1
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CA
Canada
Prior art keywords
nodes
node
network
representing
model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002412375A
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English (en)
Inventor
Thomas J. Colatsky
Adam L. Muzikant
Donna Rounds
John Jeremy Rice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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PHYSIOME SCIENCES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHYSIOME SCIENCES Inc filed Critical PHYSIOME SCIENCES Inc
Publication of CA2412375A1 publication Critical patent/CA2412375A1/fr
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

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  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Complex Calculations (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)

Abstract

L'invention concerne un modèle informatique d'un organe ainsi qu'un procédé permettant d'évaluer l'impact des différences génétiques, qui se produisent dans les cellules simples dont se compose l'organe, au niveau microscopique ainsi qu'au niveau de l'organe entier. Les différences génétiques dans le modèle reposent sur des changements de fonction ou de distribution de protéines, associés aux mutations génétiques, au sexe, à la maladie ou aux variations occasionnées par des allèles dans la configuration de l'expression des gènes.
CA002412375A 2000-06-22 2001-06-22 Systeme informatique permettant la modelisation de l'expression d'une proteine dans un organe Abandoned CA2412375A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59912800A 2000-06-22 2000-06-22
US09/599,128 2000-06-22
PCT/US2001/019918 WO2001098935A2 (fr) 2000-06-22 2001-06-22 Systeme informatique permettant la modelisation de l'expression d'une proteine dans un organe

Publications (1)

Publication Number Publication Date
CA2412375A1 true CA2412375A1 (fr) 2001-12-27

Family

ID=24398324

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002412375A Abandoned CA2412375A1 (fr) 2000-06-22 2001-06-22 Systeme informatique permettant la modelisation de l'expression d'une proteine dans un organe

Country Status (7)

Country Link
EP (1) EP1311972A2 (fr)
JP (1) JP2004508073A (fr)
AU (1) AU2001268668A1 (fr)
CA (1) CA2412375A1 (fr)
IL (1) IL152962A0 (fr)
NZ (1) NZ522699A (fr)
WO (1) WO2001098935A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7069534B2 (en) 2003-12-17 2006-06-27 Sahouria Emile Y Mask creation with hierarchy management using cover cells
US7844431B2 (en) 2004-02-20 2010-11-30 The Mathworks, Inc. Method and apparatus for integrated modeling, simulation and analysis of chemical and biochemical reactions
US8554486B2 (en) 2004-02-20 2013-10-08 The Mathworks, Inc. Method, computer program product, and apparatus for selective memory restoration of a simulation

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524818A (ja) 1999-04-16 2003-08-19 エンテロス・インコーポレーテッド コンピュータ・ベースのシステム・モデルを使用して、連結シミュレーション演算を実施する方法および装置
US7353152B2 (en) 2001-05-02 2008-04-01 Entelos, Inc. Method and apparatus for computer modeling diabetes
EP1393253A4 (fr) 2001-05-17 2009-12-16 Entelos Inc Appareil et procede concus pour valider un modele informatique
US6862561B2 (en) 2001-05-29 2005-03-01 Entelos, Inc. Method and apparatus for computer modeling a joint
US7853406B2 (en) 2003-06-13 2010-12-14 Entelos, Inc. Predictive toxicology for biological systems
JP2007511330A (ja) 2003-11-19 2007-05-10 エンテロス・インコーポレーテッド 代謝基質の利用率を評価するための装置および方法
WO2006022226A1 (fr) * 2004-08-26 2006-03-02 Kyoto University Dispositif et programme de sortie de bioparametre
US9370310B2 (en) 2007-01-18 2016-06-21 General Electric Company Determination of cellular electrical potentials
GB201005625D0 (en) 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8391091A (en) * 1990-09-21 1992-04-15 Medsim, Inc. System for simulating the physiological response of a living organism

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7069534B2 (en) 2003-12-17 2006-06-27 Sahouria Emile Y Mask creation with hierarchy management using cover cells
US7844431B2 (en) 2004-02-20 2010-11-30 The Mathworks, Inc. Method and apparatus for integrated modeling, simulation and analysis of chemical and biochemical reactions
US8234098B2 (en) 2004-02-20 2012-07-31 The Mathworks, Inc. Method and apparatus for integrated modeling, simulation and analysis of chemical and biochemical reactions
US8554486B2 (en) 2004-02-20 2013-10-08 The Mathworks, Inc. Method, computer program product, and apparatus for selective memory restoration of a simulation

Also Published As

Publication number Publication date
EP1311972A2 (fr) 2003-05-21
IL152962A0 (en) 2003-06-24
WO2001098935A3 (fr) 2003-03-13
AU2001268668A1 (en) 2002-01-02
NZ522699A (en) 2006-08-31
WO2001098935A2 (fr) 2001-12-27
JP2004508073A (ja) 2004-03-18

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20050309