CA2393699A1 - Composes d'ammonium quaternaire et leur utilisation comme agent antitussif - Google Patents
Composes d'ammonium quaternaire et leur utilisation comme agent antitussif Download PDFInfo
- Publication number
- CA2393699A1 CA2393699A1 CA002393699A CA2393699A CA2393699A1 CA 2393699 A1 CA2393699 A1 CA 2393699A1 CA 002393699 A CA002393699 A CA 002393699A CA 2393699 A CA2393699 A CA 2393699A CA 2393699 A1 CA2393699 A1 CA 2393699A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- pharmaceutically acceptable
- represented
- compound
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un mode de réalisation de la présente invention concerne l'utilisation de certains composés d'ammonium quaternaire comme substance active intervenant dans la fabrication d'un médicament servant au traitement et/ou à la prévention de la toux chez des animaux à sang chaud, y compris chez l'être humain, les composés étant représentés par la formule (I), dans laquelle J est indépendamment choisi parmi un représenté par l'une des formules (II), (III) et (IV).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002393699A CA2393699A1 (fr) | 1999-12-15 | 2000-12-15 | Composes d'ammonium quaternaire et leur utilisation comme agent antitussif |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2,292,343 | 1999-12-15 | ||
CA2292343 | 1999-12-15 | ||
PCT/CA2000/001508 WO2001044167A1 (fr) | 1999-12-15 | 2000-12-15 | Composes d'ammonium quaternaire et leur utilisation comme agent antitussif |
CA002393699A CA2393699A1 (fr) | 1999-12-15 | 2000-12-15 | Composes d'ammonium quaternaire et leur utilisation comme agent antitussif |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2393699A1 true CA2393699A1 (fr) | 2001-06-21 |
Family
ID=25681401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002393699A Abandoned CA2393699A1 (fr) | 1999-12-15 | 2000-12-15 | Composes d'ammonium quaternaire et leur utilisation comme agent antitussif |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2393699A1 (fr) |
-
2000
- 2000-12-15 CA CA002393699A patent/CA2393699A1/fr not_active Abandoned
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6362197B1 (en) | Compositions and method for treatment of cough | |
US20040214867A1 (en) | Quaternary salts of n-substituted cyclic or acyclic amines as pharmaceuticals | |
US20030166629A1 (en) | Cyclic quaternary ammonium compounds | |
EP0581167B1 (fr) | Dérivés de arylglycinamide, leur procédé de préparation et leur usage pour le traitement de la dysurie | |
CA2393699A1 (fr) | Composes d'ammonium quaternaire et leur utilisation comme agent antitussif | |
AU761663B2 (en) | Quarternary ammonium compounds as anti-tussive agents | |
US20030181489A1 (en) | Quaternary ammonium and their use as anti-tussive agent | |
CA2393711A1 (fr) | Sels quaternaires d'amines cycliques ou acycliques substituees comme principes pharmaceutiques | |
CA2393706A1 (fr) | Composes cycliques d'ammonium quaternaire | |
AU2003231702B2 (en) | Quaternary ammonium compounds as anti-tussive agents | |
AU660832B2 (en) | Tetrahydronaphthalene derivatives, their preparation and their application in therapy | |
CA2217479C (fr) | Derives de la phenoxyethylamine possedant une haute affinite pour le recepteur 5-ht1a, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant | |
MXPA00012239A (en) | Quarternary ammonium compounds as anti-tussive agents |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |