CA2372316A1 - Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique - Google Patents

Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique Download PDF

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Publication number
CA2372316A1
CA2372316A1 CA002372316A CA2372316A CA2372316A1 CA 2372316 A1 CA2372316 A1 CA 2372316A1 CA 002372316 A CA002372316 A CA 002372316A CA 2372316 A CA2372316 A CA 2372316A CA 2372316 A1 CA2372316 A1 CA 2372316A1
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CA
Canada
Prior art keywords
cells
proteasome
lac
activity
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002372316A
Other languages
English (en)
Inventor
Jiangping Wu
Xin Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Montreal
Centre de Recherche du Centre Hospitalier de lUniversite de Montreal
Original Assignee
Universite de Montreal
Centre de Recherche du Centre Hospitalier de lUniversite de Montreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Montreal, Centre de Recherche du Centre Hospitalier de lUniversite de Montreal filed Critical Universite de Montreal
Priority to CA002372316A priority Critical patent/CA2372316A1/fr
Publication of CA2372316A1 publication Critical patent/CA2372316A1/fr
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002372316A 2002-02-21 2002-02-21 Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique Abandoned CA2372316A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002372316A CA2372316A1 (fr) 2002-02-21 2002-02-21 Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002372316A CA2372316A1 (fr) 2002-02-21 2002-02-21 Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique

Publications (1)

Publication Number Publication Date
CA2372316A1 true CA2372316A1 (fr) 2003-08-21

Family

ID=27792722

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002372316A Abandoned CA2372316A1 (fr) 2002-02-21 2002-02-21 Utilisation d'inhibiteurs de proteasome pour le traitement du cancer, des inflammations, des maladies autoimmunes, des rejets de greffes, et du choc septique

Country Status (1)

Country Link
CA (1) CA2372316A1 (fr)

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20060221