CA2370767A1 - 49 proteines humaines secretees - Google Patents

49 proteines humaines secretees Download PDF

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Publication number
CA2370767A1
CA2370767A1 CA002370767A CA2370767A CA2370767A1 CA 2370767 A1 CA2370767 A1 CA 2370767A1 CA 002370767 A CA002370767 A CA 002370767A CA 2370767 A CA2370767 A CA 2370767A CA 2370767 A1 CA2370767 A1 CA 2370767A1
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Canada
Prior art keywords
human
seq
sequence
polypeptide
soares
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Abandoned
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CA002370767A
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English (en)
Inventor
Craig A. Rosen
Steven M. Ruben
George Komatsoulis
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Human Genome Sciences Inc
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Individual
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Publication of CA2370767A1 publication Critical patent/CA2370767A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Pulmonology (AREA)
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  • Immunology (AREA)
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  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
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  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
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Abstract

La présente invention concerne de nouvelles protéines humaines sécrétées et des acides nucléiques isolés qui contiennent les régions codantes des gènes codant pour ces protéines. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps, et des procédés de recombinaison pour produire ces protéines humaines sécrétées. L'invention concerne de plus des méthodes diagnostiques et thérapeutiques utiles pour diagnostiquer et traiter des maladies, des affections et/ou des états pathologiques liées à ces nouvelles protéines humaines sécrétées.
CA002370767A 1999-04-09 2000-04-06 49 proteines humaines secretees Abandoned CA2370767A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12870299P 1999-04-09 1999-04-09
US60/128,702 1999-04-09
US17704900P 2000-01-20 2000-01-20
US60/177,049 2000-01-20
PCT/US2000/009069 WO2000061620A1 (fr) 1999-04-09 2000-04-06 49 proteines humaines secretees

Publications (1)

Publication Number Publication Date
CA2370767A1 true CA2370767A1 (fr) 2000-10-19

Family

ID=26826865

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002370767A Abandoned CA2370767A1 (fr) 1999-04-09 2000-04-06 49 proteines humaines secretees

Country Status (5)

Country Link
EP (1) EP1173477A4 (fr)
JP (1) JP2003501009A (fr)
AU (1) AU4074500A (fr)
CA (1) CA2370767A1 (fr)
WO (1) WO2000061620A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034135B2 (en) 2000-05-03 2006-04-25 Millennium Pharmaceuticals, Inc. Molecules of the NBS/LRR protein family and uses thereof
WO2001083753A2 (fr) * 2000-05-03 2001-11-08 Millennium Pharmaceuticals, Inc. Nouvelles molecules appartenant a la famille de proteines nbs/lrr et utilisations de ces dernieres
AP2007003921A0 (en) 2004-08-16 2007-02-28 Atugen Ag Therapeutic uses of inhibitors of rtp801
US7825099B2 (en) 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
DOP2007000015A (es) 2006-01-20 2007-08-31 Quark Biotech Inc Usos terapéuticos de inhibidores de rtp801
GB2450840B (en) 2006-05-11 2010-12-29 Quark Pharmaceuticals Inc Screening Systems Utilizing RTP801
WO2007141796A2 (fr) 2006-06-09 2007-12-13 Quark Pharmaceuticals, Inc. Utilisations thérapeutiques d'inhibiteurs de rtp801l
US7872119B2 (en) 2007-02-26 2011-01-18 Quark Pharmaceuticals, Inc. Inhibitors of RTP801 and their use in disease treatment
US8614311B2 (en) 2007-12-12 2013-12-24 Quark Pharmaceuticals, Inc. RTP801L siRNA compounds and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
US5707829A (en) * 1995-08-11 1998-01-13 Genetics Institute, Inc. DNA sequences and secreted proteins encoded thereby
AU5828398A (en) * 1997-01-24 1998-08-18 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
WO1998039448A2 (fr) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 nouvelles proteines secretees
EP1025128A1 (fr) * 1997-09-03 2000-08-09 The University of Mississippi Medical Center Molecules d'adn codant des polypeptides receptifs a l'imidazoline et polypeptides codes par cet adn

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Publication number Publication date
EP1173477A1 (fr) 2002-01-23
EP1173477A4 (fr) 2003-02-26
AU4074500A (en) 2000-11-14
JP2003501009A (ja) 2003-01-14
WO2000061620A1 (fr) 2000-10-19

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