CA2368681A1 - Peptides intestinaux anti-angiogeniques, zdint5 - Google Patents

Peptides intestinaux anti-angiogeniques, zdint5 Download PDF

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Publication number
CA2368681A1
CA2368681A1 CA002368681A CA2368681A CA2368681A1 CA 2368681 A1 CA2368681 A1 CA 2368681A1 CA 002368681 A CA002368681 A CA 002368681A CA 2368681 A CA2368681 A CA 2368681A CA 2368681 A1 CA2368681 A1 CA 2368681A1
Authority
CA
Canada
Prior art keywords
polypeptide
seq
zdint5
gly
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002368681A
Other languages
English (en)
Inventor
James L. Holloway
Paul O. Sheppard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2368681A1 publication Critical patent/CA2368681A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

La présente invention concerne des molécules polynucléotides et polypeptides, et des variantes de celles-ci, destinées à des zdint5, un nouveau membre des désintégrines protéases. Les polypeptides et les polynucléotides codant ces désintégrines protéases exercent un effet modulateur sur l'interaction intercellulaire et peuvent être mis en application sur le plan médical et thérapeutique. La présente invention concerne également des anticorps de polypeptides de zdint5.
CA002368681A 2000-02-10 2001-02-09 Peptides intestinaux anti-angiogeniques, zdint5 Abandoned CA2368681A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50180600A 2000-02-10 2000-02-10
US09/501,806 2000-02-10
PCT/US2001/004198 WO2001059112A1 (fr) 2000-02-10 2001-02-09 Peptides intestinaux anti-angiogeniques, zdint5

Publications (1)

Publication Number Publication Date
CA2368681A1 true CA2368681A1 (fr) 2001-08-16

Family

ID=23995100

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002368681A Abandoned CA2368681A1 (fr) 2000-02-10 2001-02-09 Peptides intestinaux anti-angiogeniques, zdint5

Country Status (5)

Country Link
EP (1) EP1171602A1 (fr)
JP (1) JP2004500087A (fr)
AU (1) AU3681601A (fr)
CA (1) CA2368681A1 (fr)
WO (1) WO2001059112A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002218196A1 (en) * 2000-09-28 2002-04-08 Bayer Aktiengesellschaft Regulation of human adam-ts-like protein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136665A0 (en) * 1997-12-08 2001-06-14 Beth Israel Hospital Mutants of endostatin, "em 1" having anti-angiogenic activity and methods of use thereof
KR100682666B1 (ko) * 1998-06-17 2007-02-15 베쓰 이스라엘 디코니스 메디칼 센터 인크 항혈관형성 단백질 및 이들을 사용하는 방법
WO2000003726A1 (fr) * 1998-07-14 2000-01-27 Bristol-Myers Squibb Company Fragments de l'angiostatine se liant a la lysine

Also Published As

Publication number Publication date
EP1171602A1 (fr) 2002-01-16
WO2001059112A1 (fr) 2001-08-16
JP2004500087A (ja) 2004-01-08
AU3681601A (en) 2001-08-20

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Legal Events

Date Code Title Description
FZDE Discontinued