CA2368370A1 - The use of dienogest in high dosages - Google Patents
The use of dienogest in high dosages Download PDFInfo
- Publication number
- CA2368370A1 CA2368370A1 CA002368370A CA2368370A CA2368370A1 CA 2368370 A1 CA2368370 A1 CA 2368370A1 CA 002368370 A CA002368370 A CA 002368370A CA 2368370 A CA2368370 A CA 2368370A CA 2368370 A1 CA2368370 A1 CA 2368370A1
- Authority
- CA
- Canada
- Prior art keywords
- dienogest
- high dosages
- breast
- mastopathic
- changes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 title abstract 4
- 229960003309 dienogest Drugs 0.000 title abstract 4
- 210000000481 breast Anatomy 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000030270 breast disease Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The use of dienogest in high dosages for reducing the body of the breast is described.
Furthermore, retrogression of mastopathic changes in the body of the breast can also be brought about. Dienogest is also outstandingly suitable for the prophylaxis of mastopathies. In high dosages, dienogest prevents the formation of mastopathic changes in the body of the breast.
Furthermore, retrogression of mastopathic changes in the body of the breast can also be brought about. Dienogest is also outstandingly suitable for the prophylaxis of mastopathies. In high dosages, dienogest prevents the formation of mastopathic changes in the body of the breast.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19908762.8 | 1999-02-18 | ||
| DE19908762A DE19908762A1 (en) | 1999-02-18 | 1999-02-18 | Use of dienogest in high doses |
| PCT/EP2000/000982 WO2000048604A1 (en) | 1999-02-18 | 2000-02-08 | Utilization of dienogest in high doses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2368370A1 true CA2368370A1 (en) | 2000-08-24 |
| CA2368370C CA2368370C (en) | 2008-05-06 |
Family
ID=7899230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002368370A Expired - Fee Related CA2368370C (en) | 1999-02-18 | 2000-02-08 | The use of dienogest in high dosages |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6670350B1 (en) |
| EP (1) | EP1150683B9 (en) |
| JP (1) | JP4233766B2 (en) |
| AT (1) | ATE251459T1 (en) |
| AU (1) | AU2802700A (en) |
| CA (1) | CA2368370C (en) |
| CL (1) | CL2004000579A1 (en) |
| DE (2) | DE19908762A1 (en) |
| DK (1) | DK1150683T3 (en) |
| ES (1) | ES2208278T3 (en) |
| PT (1) | PT1150683E (en) |
| WO (1) | WO2000048604A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004019743B4 (en) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Multiphase preparation for contraception based on natural estrogen |
| US8153616B2 (en) * | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (en) * | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Application of estradiol valerate or 17ß-estradiol in combination with dienogest for oral therapy to maintain and/or increase the female libido |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1593515C3 (en) * | 1966-08-11 | 1975-08-14 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 6-chloro-21-fluoro-1,2alpha-methylen-DeKa high 4,6-prepregnadienes, processes for their production and agents containing them |
| FR2515041A1 (en) * | 1981-10-26 | 1983-04-29 | Besins Jean | PROGESTERONE-BASED DRUG FOR THE TREATMENT OF MAMMARY DISEASES |
| ES2176218T3 (en) * | 1993-11-19 | 2002-12-01 | Jenapharm Gmbh | CARCINOSTATIC AGENT FOR HORMONAL THERAPY CONTAINING DIENOGEST AS ACTIVE COMPONENT. |
| DE19654609A1 (en) * | 1996-12-20 | 1998-06-25 | Schering Ag | Therapeutic progestogens for the treatment of premenstrual dysphoric disorder |
-
1999
- 1999-02-18 DE DE19908762A patent/DE19908762A1/en not_active Withdrawn
-
2000
- 2000-02-08 ES ES00906295T patent/ES2208278T3/en not_active Expired - Lifetime
- 2000-02-08 PT PT00906295T patent/PT1150683E/en unknown
- 2000-02-08 AT AT00906295T patent/ATE251459T1/en not_active IP Right Cessation
- 2000-02-08 AU AU28027/00A patent/AU2802700A/en not_active Abandoned
- 2000-02-08 JP JP2000599396A patent/JP4233766B2/en not_active Expired - Lifetime
- 2000-02-08 DE DE50003993T patent/DE50003993D1/en not_active Expired - Fee Related
- 2000-02-08 US US09/913,554 patent/US6670350B1/en not_active Expired - Fee Related
- 2000-02-08 DK DK00906295T patent/DK1150683T3/en active
- 2000-02-08 EP EP00906295A patent/EP1150683B9/en not_active Expired - Lifetime
- 2000-02-08 CA CA002368370A patent/CA2368370C/en not_active Expired - Fee Related
- 2000-02-08 WO PCT/EP2000/000982 patent/WO2000048604A1/en not_active Ceased
-
2004
- 2004-03-19 CL CL200400579A patent/CL2004000579A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1150683E (en) | 2004-03-31 |
| EP1150683B1 (en) | 2003-10-08 |
| EP1150683B9 (en) | 2004-01-14 |
| EP1150683A1 (en) | 2001-11-07 |
| ATE251459T1 (en) | 2003-10-15 |
| JP4233766B2 (en) | 2009-03-04 |
| WO2000048604A1 (en) | 2000-08-24 |
| ES2208278T3 (en) | 2004-06-16 |
| DK1150683T3 (en) | 2004-02-09 |
| JP2002537261A (en) | 2002-11-05 |
| DE50003993D1 (en) | 2003-11-13 |
| DE19908762A1 (en) | 2000-08-31 |
| US6670350B1 (en) | 2003-12-30 |
| CA2368370C (en) | 2008-05-06 |
| CL2004000579A1 (en) | 2005-01-07 |
| AU2802700A (en) | 2000-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |