CA2355779C - Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum - Google Patents

Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum Download PDF

Info

Publication number
CA2355779C
CA2355779C CA002355779A CA2355779A CA2355779C CA 2355779 C CA2355779 C CA 2355779C CA 002355779 A CA002355779 A CA 002355779A CA 2355779 A CA2355779 A CA 2355779A CA 2355779 C CA2355779 C CA 2355779C
Authority
CA
Canada
Prior art keywords
coating
gum
active agent
added
caffeine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002355779A
Other languages
English (en)
Other versions
CA2355779A1 (fr
Inventor
Sonya S. Johnson
David W. Record
Michael J. Greenberg
Michael A. Reed
Victor V. Gudas
Philip G. Schnell
Donald A. Seielstad
Henry T. Tyrpin
Michael P. Russell
David L. Witkewitz
Joo H. Song
Donald J. Townsend
Robert J. Yatka
Ronald L. Ream
Christine L. Corriveau
William J. Wokas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WM Wrigley Jr Co
Original Assignee
WM Wrigley Jr Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WM Wrigley Jr Co filed Critical WM Wrigley Jr Co
Priority claimed from PCT/US1999/029742 external-priority patent/WO2000035296A1/fr
Publication of CA2355779A1 publication Critical patent/CA2355779A1/fr
Application granted granted Critical
Publication of CA2355779C publication Critical patent/CA2355779C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
    • A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention un procédé de production d'un chewing-gum permettant de mieux libérer un agent actif, et concerne également le chewing-gum ainsi produit. On obtient ce chewing-gum en ajoutant un agent actif à l'enrobage d'un chewing-gum. On ajoute l'agent actif à l'enrobage dans une solution d'enrobage, ou en le prémélange avec un arôme ou un solvant. La solution d'enrobage peut contenir un édulcorant ou d'autres agents stimulateurs transdermiques pour augmenter l'absorption transmuqueuse. Par ailleurs, on peut utiliser un agent actif dans la partie centrale du chewing-gum.
CA002355779A 1998-12-15 1999-12-14 Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum Expired - Fee Related CA2355779C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11238998P 1998-12-15 1998-12-15
US60/112,389 1998-12-15
US28681899A 1999-04-06 1999-04-06
US09/286,818 1999-04-06
US38921199A 1999-09-02 1999-09-02
US09/389,211 1999-09-02
PCT/US1999/029742 WO2000035296A1 (fr) 1996-11-27 1999-12-14 Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum

Publications (2)

Publication Number Publication Date
CA2355779A1 CA2355779A1 (fr) 2000-06-22
CA2355779C true CA2355779C (fr) 2006-02-07

Family

ID=27381160

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002355779A Expired - Fee Related CA2355779C (fr) 1998-12-15 1999-12-14 Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum

Country Status (5)

Country Link
EP (2) EP1139774A4 (fr)
CN (1) CN1330516A (fr)
AU (1) AU765999B2 (fr)
BR (1) BR9916303A (fr)
CA (1) CA2355779C (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8323683B2 (en) * 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
CN102008473B (zh) * 2010-11-23 2014-12-17 中国人民解放军第二军医大学 尼古丁的应用和一种药物组合物
MX2020001445A (es) * 2017-08-18 2020-03-20 Intercontinental Great Brands Llc Composiciones de goma de mascar y metodos para su preparacion.
EP4090320A1 (fr) * 2020-01-15 2022-11-23 McNeil AB Produit et procédé de fabrication d'une gomme
US11272799B2 (en) * 2020-05-29 2022-03-15 Unistraw Corp. Drinking straw with internal coating

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1298670A (en) * 1915-06-11 1919-04-01 Stuart W Cramer Chewing-gum.
US3011949A (en) * 1958-06-10 1961-12-05 Anthony G Bilotti Method of promoting release of active ingredients from slab chewing gum and product
FR2345938A1 (fr) * 1976-03-05 1977-10-28 Choay Patrick Gommes a macher douees de proprietes stimulantes
US4238475A (en) * 1979-08-01 1980-12-09 Life Savers Inc. Chewing cum capable of releasing finely divided water-insoluble materials therefrom
US4971787A (en) * 1984-08-27 1990-11-20 Warner-Lambert Company Antacid chewing gum
US5013716A (en) * 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
US4997659A (en) * 1989-03-28 1991-03-05 The Wm. Wrigley Jr. Company Alitame stability in chewing gum by encapsulation
US5139794A (en) * 1989-04-19 1992-08-18 Wm. Wrigley Jr. Company Use of encapsulated salts in chewing gum
DK365389D0 (da) * 1989-07-24 1989-07-24 Fertin Lab As Antifungalt tyggegummipraeparat
US5270061A (en) * 1992-03-26 1993-12-14 Wm. Wrigley Jr. Company Dual composition hard coated gum with improved shelf life
US5286502A (en) * 1992-04-21 1994-02-15 Wm. Wrigley Jr. Company Use of edible film to prolong chewing gum shelf life
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
JPH09502615A (ja) * 1993-09-15 1997-03-18 ダブリューエム リグリー ジュニア カンパニー エリスリトールを含有する硬質被膜を有するチューイングガムペレット
CA2170497C (fr) * 1993-09-15 1999-07-13 Michael A. Reed Gomme a macher a revetement rigide de polyols mixtes, et duree de vie prolongee
AU6591696A (en) * 1995-07-26 1997-02-26 Wm. Wrigley Jr. Company Use of encapsulated aspartic acid sweeteners in coating syrups for coated pellet chewing gums
CA2271889C (fr) * 1996-11-27 2004-01-27 Wm. Wrigley Jr. Company Procede permettant de reguler la liberation de cafeine dans de la gomme a macher et gomme ainsi produite

Also Published As

Publication number Publication date
EP1139774A4 (fr) 2002-06-12
AU765999B2 (en) 2003-10-09
EP1221863A1 (fr) 2002-07-17
EP1221863A4 (fr) 2003-03-26
CA2355779A1 (fr) 2000-06-22
EP1139774A1 (fr) 2001-10-10
BR9916303A (pt) 2001-10-02
CN1330516A (zh) 2002-01-09
AU2184300A (en) 2000-07-03

Similar Documents

Publication Publication Date Title
US6627234B1 (en) Method of producing active agent coated chewing gum products
US6949264B1 (en) Nutraceuticals or nutritional supplements and method of making
US7163705B2 (en) Coated chewing gum product and method of making
WO2000035296A1 (fr) Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum
US6350480B1 (en) Chewing gum product including a hydrophilic gum base and method of producing
US6586023B1 (en) Process for controlling release of active agents from a chewing gum coating and product thereof
US6773716B2 (en) Over-coated chewing gum formulations
US6613346B2 (en) Chewable product including active ingredient
EP1817014B1 (fr) Méthode pour apporter une sédation apide à un consommateur de chewing gum de nicotine
WO2008045579A1 (fr) Véhicules d'administration orale contenant un médicament traditionnel chinois ou un extrait de celui-ci
WO2000025598A1 (fr) Esters d'acide gras de saccharose prevus pour augmenter la liberation d'ingredients actifs
WO2002013781A1 (fr) Procede de preparation d'une gomme a macher ayant un gout agreable pour le consommateur
AU1937700A (en) Controlling release of active agents from a chewing gum coating
US20080181933A1 (en) Chewing Gum Compositions of Varenicline
CA2394290C (fr) Chewing gum a liberation de principes actifs lipophiles
US20030180414A1 (en) Method of controlling release of bitterness inhibitors in chewing gum and gum produced thereby
US20100104518A1 (en) Chewing gum, confection, and other oral delivery vehicles containing a traditional chinese medicine or extract thereof
CA2355779C (fr) Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum
AU2004200574B2 (en) Controlling Release of Active Agents from a Chewing Gum Coating
JUNO et al. PHARMACEUTICAL SCIENCES

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed