CA2351146A1 - Chimiokine cxc h174 et techniques permettant de prevenir des lesions du systeme nerveux - Google Patents

Chimiokine cxc h174 et techniques permettant de prevenir des lesions du systeme nerveux Download PDF

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Publication number
CA2351146A1
CA2351146A1 CA002351146A CA2351146A CA2351146A1 CA 2351146 A1 CA2351146 A1 CA 2351146A1 CA 002351146 A CA002351146 A CA 002351146A CA 2351146 A CA2351146 A CA 2351146A CA 2351146 A1 CA2351146 A1 CA 2351146A1
Authority
CA
Canada
Prior art keywords
amino acid
chemokine
protein
cells
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002351146A
Other languages
English (en)
Inventor
Kenneth Jacobs
John M. Mccoy
Edward R. Lavallie
Lisa A. Collins-Racie
Zhijian Lu
Sha Mi
Kerry Kelleher
Mckeough Carlin-Duckett
Martin E. Dorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Genetics Institute LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2351146A1 publication Critical patent/CA2351146A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des polynucléotides comprenant des séquences codant la chimiokine CXC H174 ou ses formes modifiées, la chimiokine CXC H174 codée et ses formes modifiées, des procédés d'identification des inhibiteurs de l'interaction entre H174 et ses récepteurs, ainsi que des techniques de traitement de pathologies du système nerveux impliquant H174.
CA002351146A 1998-11-16 1999-11-16 Chimiokine cxc h174 et techniques permettant de prevenir des lesions du systeme nerveux Abandoned CA2351146A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19309298A 1998-11-16 1998-11-16
US09/193,092 1998-11-16
PCT/US1999/027199 WO2000029439A1 (fr) 1998-11-16 1999-11-16 Chimiokine cxc h174 et techniques permettant de prevenir des lesions du systeme nerveux

Publications (1)

Publication Number Publication Date
CA2351146A1 true CA2351146A1 (fr) 2000-05-25

Family

ID=22712256

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002351146A Abandoned CA2351146A1 (fr) 1998-11-16 1999-11-16 Chimiokine cxc h174 et techniques permettant de prevenir des lesions du systeme nerveux

Country Status (4)

Country Link
EP (1) EP1133521A1 (fr)
AU (1) AU1729900A (fr)
CA (1) CA2351146A1 (fr)
WO (1) WO2000029439A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3116887B1 (fr) 2014-03-13 2021-02-17 Universität Basel Ligands de type carbohydrate se liant aux anticorps de la glycoprotéine associée à la myéline
WO2017046172A1 (fr) 2015-09-16 2017-03-23 Universität Basel Ligands glucidiques se liant à des anticorps dirigés contre des glycoépitopes de glycosphingolipides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998011138A1 (fr) * 1996-09-12 1998-03-19 Human Genome Sciences, Inc. Chimiokine alpha-4
EP0887409A1 (fr) * 1997-06-26 1998-12-30 Ernst Werner Chemokine MIG-bêta: fragment d'ADNc, protéine, vecteur d'expression, cellule transformée, méthodes de diagnostic et compositions pharmaceutiques

Also Published As

Publication number Publication date
EP1133521A1 (fr) 2001-09-19
WO2000029439A1 (fr) 2000-05-25
AU1729900A (en) 2000-06-05
WO2000029439A9 (fr) 2000-11-09

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Legal Events

Date Code Title Description
FZDE Discontinued