CA2348024A1 - Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof - Google Patents

Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof Download PDF

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Publication number
CA2348024A1
CA2348024A1 CA002348024A CA2348024A CA2348024A1 CA 2348024 A1 CA2348024 A1 CA 2348024A1 CA 002348024 A CA002348024 A CA 002348024A CA 2348024 A CA2348024 A CA 2348024A CA 2348024 A1 CA2348024 A1 CA 2348024A1
Authority
CA
Canada
Prior art keywords
oral administration
straw
pharmaceutical composition
granular
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002348024A
Other languages
French (fr)
Other versions
CA2348024C (en
Inventor
Joseph M. Morris
James S. Beahm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
Mcneil-Ppc, Inc.
Joseph M. Morris
James S. Beahm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil-Ppc, Inc., Joseph M. Morris, James S. Beahm filed Critical Mcneil-Ppc, Inc.
Publication of CA2348024A1 publication Critical patent/CA2348024A1/en
Application granted granted Critical
Publication of CA2348024C publication Critical patent/CA2348024C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol

Abstract

This invention provides a dry, granular, free-flowing, stable pharmaceutical composition for oral administration comprising particles of medicament or nutrient coated with a suitable taste-masking agent, a salivation-inducing agent, and a pharmaceutically acceptable carrier.
This invention also provides dosage forms for oral administration comprising a closed, moisture-resistant container, either straw-like or non-straw-like, each having therein a single unit dose of the instant pharmaceutical composition, and having an opening means for permitting the dry oral administration thereof.
CA002348024A 1998-10-30 1999-10-28 Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof Expired - Fee Related CA2348024C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10630298P 1998-10-30 1998-10-30
US60/106,302 1998-10-30
PCT/US1999/025454 WO2000025744A1 (en) 1998-10-30 1999-10-28 Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof

Publications (2)

Publication Number Publication Date
CA2348024A1 true CA2348024A1 (en) 2000-05-11
CA2348024C CA2348024C (en) 2008-02-19

Family

ID=22310679

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002348024A Expired - Fee Related CA2348024C (en) 1998-10-30 1999-10-28 Granular, free-flowing pharmaceutical composition, and straw-like dosage form for oral administration thereof

Country Status (4)

Country Link
JP (1) JP2002528483A (en)
AU (1) AU1240800A (en)
CA (1) CA2348024C (en)
WO (1) WO2000025744A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
DE102006007830A1 (en) * 2006-02-17 2007-08-30 Grünenthal GmbH Storage-stable oral dosage form of amoxicillin and clavulanic acid
RS59667B1 (en) 2013-03-15 2020-01-31 Braintree Laboratories Inc Dual use oral pharmaceutical composition tablets of sulfate saltes and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ226822A (en) * 1987-11-16 1990-03-27 Mcneil Consumer Prod Chewable medicament tablet containing means for taste masking
US4981468A (en) * 1989-02-17 1991-01-01 Eli Lilly And Company Delivery device for orally administered therapeutic agents
CH687615A5 (en) * 1994-09-07 1997-01-15 R W Johnson Pharmaceutical Res Tropical packaging.
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
IT1276160B1 (en) * 1995-11-22 1997-10-27 Recordati Chem Pharm READY-RELEASE ORAL PHARMACEUTICAL COMPOSITIONS FOR EXTEMPORARY SUSPENSIONS
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system

Also Published As

Publication number Publication date
WO2000025744A1 (en) 2000-05-11
CA2348024C (en) 2008-02-19
JP2002528483A (en) 2002-09-03
AU1240800A (en) 2000-05-22

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20181029