CA2345642A1 - Procedes pour traiter les troubles non thyroidiens - Google Patents
Procedes pour traiter les troubles non thyroidiens Download PDFInfo
- Publication number
- CA2345642A1 CA2345642A1 CA002345642A CA2345642A CA2345642A1 CA 2345642 A1 CA2345642 A1 CA 2345642A1 CA 002345642 A CA002345642 A CA 002345642A CA 2345642 A CA2345642 A CA 2345642A CA 2345642 A1 CA2345642 A1 CA 2345642A1
- Authority
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- Prior art keywords
- igf
- igfbp
- thyroid
- disorder
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/33—Heterocyclic compounds
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Molecular Biology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des procédés permettant de traiter les troubles non thyroïdiens qui répondent à IGF, à IGFBP-3, ou qui sont indépendants de IGF. Les agonistes du tronc thyro-cervical et IGF sont administrés à des sujets souffrant de troubles non thyroïdiens répondant à IGF, afin d'atténuer les symptômes de ces troubles. Les antagonistes du tronc thyro-cervical et IGFBP-3 sont administrés à des sujets souffrant de troubles non thyroïdiens répondant à IGFBP-3, afin d'atténuer les symptômes de ces troubles. Enfin, les antagonistes du tronc thyro-cervical sont administrés aux sujets souffrant de troubles non thyroïdiens dépendants de IGF, afin d'atténuer les symptômes de ces troubles.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10279098P | 1998-10-02 | 1998-10-02 | |
| US39913499A | 1999-09-20 | 1999-09-20 | |
| US09/399,134 | 1999-09-20 | ||
| US60/102,790 | 1999-09-20 | ||
| PCT/US1999/022761 WO2000020024A2 (fr) | 1998-10-02 | 1999-09-29 | Procedes pour traiter les troubles non thyroidiens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2345642A1 true CA2345642A1 (fr) | 2000-04-13 |
Family
ID=26799734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002345642A Abandoned CA2345642A1 (fr) | 1998-10-02 | 1999-09-29 | Procedes pour traiter les troubles non thyroidiens |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1117425A2 (fr) |
| JP (1) | JP2002526417A (fr) |
| AU (1) | AU6407099A (fr) |
| CA (1) | CA2345642A1 (fr) |
| WO (1) | WO2000020024A2 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001291090B2 (en) | 2000-09-19 | 2007-05-10 | Bioexpertise, Llc | Method for use of IGF-binding protein for selective sensitization of target cells in vivo |
| EP2065038A1 (fr) | 2007-11-30 | 2009-06-03 | Pharnext | Nouvelles approches thérapeutiques pour traiter la maladie de Charcot-Marie-Tooth |
| EP2135607A1 (fr) | 2008-06-18 | 2009-12-23 | Pharnext | Combinaison de pilocarpine et methimazol pour le traitement de la maladie de Charcot-MarieTooth et des troubles associés |
| US9393241B2 (en) | 2009-06-02 | 2016-07-19 | Pharnext | Compositions for treating CMT and related disorders |
| EP2263665A1 (fr) | 2009-06-02 | 2010-12-22 | Pharnext | Nouvelles compositions pour traiter le CMT et troubles associés |
| SI3003268T1 (sl) | 2013-06-05 | 2019-01-31 | Pharnext | Stabilne oralne raztopine za kombinirane API |
| US10383870B2 (en) | 2016-06-10 | 2019-08-20 | Pharnext | Early treatment of CMT disease |
| WO2019098811A2 (fr) * | 2017-11-20 | 2019-05-23 | 주식회사 노브메타파마 | Composition pour prévenir, soulager ou traiter des maladies de perte osseuse, comprenant cyclo(his-pro) (chp) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818531A (en) * | 1985-02-06 | 1989-04-04 | Eli Lilly And Company | Growth hormone and thyroid hormone |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| MD1486G2 (ro) * | 1992-10-29 | 2001-11-30 | Genentech, Inc. | Metodă de tratament sau profilaxie a obezităţii |
| US5310742A (en) * | 1992-11-30 | 1994-05-10 | Elias Alan N | Uses for thioureylenes |
| EP0726911B1 (fr) * | 1993-09-20 | 2002-10-30 | Celtrix Pharmaceuticals, Inc. | Traitement de troubles hematologiques a l'aide d'un complexe des igf-1/igfbp-3 |
| US6015786A (en) * | 1997-02-25 | 2000-01-18 | Celtrix Pharmaceuticals, Inc. | Method for increasing sex steroid levels using IGF or IGF/IGFBP-3 |
-
1999
- 1999-09-29 WO PCT/US1999/022761 patent/WO2000020024A2/fr not_active Application Discontinuation
- 1999-09-29 AU AU64070/99A patent/AU6407099A/en not_active Abandoned
- 1999-09-29 EP EP99951681A patent/EP1117425A2/fr not_active Withdrawn
- 1999-09-29 CA CA002345642A patent/CA2345642A1/fr not_active Abandoned
- 1999-09-29 JP JP2000573383A patent/JP2002526417A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000020024A2 (fr) | 2000-04-13 |
| WO2000020024A3 (fr) | 2000-07-06 |
| EP1117425A2 (fr) | 2001-07-25 |
| JP2002526417A (ja) | 2002-08-20 |
| AU6407099A (en) | 2000-04-26 |
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