CA2340475A1 - Orphan receptor - Google Patents

Orphan receptor Download PDF

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Publication number
CA2340475A1
CA2340475A1 CA002340475A CA2340475A CA2340475A1 CA 2340475 A1 CA2340475 A1 CA 2340475A1 CA 002340475 A CA002340475 A CA 002340475A CA 2340475 A CA2340475 A CA 2340475A CA 2340475 A1 CA2340475 A1 CA 2340475A1
Authority
CA
Canada
Prior art keywords
amino acid
acid sequence
receptor
relates
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002340475A
Other languages
French (fr)
Other versions
CA2340475C (en
Inventor
George G.J.M. Kuiper
Eva Enmark
Jan Ake Gustafsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karo Pharma AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9518272.1A external-priority patent/GB9518272D0/en
Priority claimed from GBGB9605550.4A external-priority patent/GB9605550D0/en
Priority claimed from GBGB9607532.0A external-priority patent/GB9607532D0/en
Priority claimed from GBGB9609576.5A external-priority patent/GB9609576D0/en
Application filed by Individual filed Critical Individual
Priority claimed from CA002201098A external-priority patent/CA2201098C/en
Publication of CA2340475A1 publication Critical patent/CA2340475A1/en
Application granted granted Critical
Publication of CA2340475C publication Critical patent/CA2340475C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed "ER.beta." having the amino acid sequence of Figs. 1,13A or 14A or substantially the same amino acid sequence as the amino acid sequence shown in Figs. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA
sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
CA002340475A 1995-09-08 1996-09-09 Orphan receptor Expired - Fee Related CA2340475C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB9518272.1 1995-09-08
GBGB9518272.1A GB9518272D0 (en) 1995-09-08 1995-09-08 Orphan receptor
GBGB9605550.4A GB9605550D0 (en) 1996-03-15 1996-03-15 Orphan receptor
GB9605550.4 1996-03-15
GB9607532.0 1996-04-11
GBGB9607532.0A GB9607532D0 (en) 1996-04-11 1996-04-11 Orphan receptor
GBGB9609576.5A GB9609576D0 (en) 1996-05-08 1996-05-08 Orphan receptor
GB9609576.5 1996-05-08
CA002201098A CA2201098C (en) 1995-09-08 1996-09-09 Orphan receptor

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002201098A Division CA2201098C (en) 1995-09-08 1996-09-09 Orphan receptor

Publications (2)

Publication Number Publication Date
CA2340475A1 true CA2340475A1 (en) 1997-03-13
CA2340475C CA2340475C (en) 2002-08-20

Family

ID=27508619

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002340475A Expired - Fee Related CA2340475C (en) 1995-09-08 1996-09-09 Orphan receptor

Country Status (1)

Country Link
CA (1) CA2340475C (en)

Also Published As

Publication number Publication date
CA2340475C (en) 2002-08-20

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20140909