CA2336093C - Improved method for mixing and processing specimen samples - Google Patents

Improved method for mixing and processing specimen samples Download PDF

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Publication number
CA2336093C
CA2336093C CA002336093A CA2336093A CA2336093C CA 2336093 C CA2336093 C CA 2336093C CA 002336093 A CA002336093 A CA 002336093A CA 2336093 A CA2336093 A CA 2336093A CA 2336093 C CA2336093 C CA 2336093C
Authority
CA
Canada
Prior art keywords
particulate matter
cover
container
sample
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002336093A
Other languages
English (en)
French (fr)
Other versions
CA2336093A1 (en
Inventor
Mariana El-Amin
Raouf A. Guirguis
Nashed Samaan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lamina Inc
Original Assignee
Lamina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lamina Inc filed Critical Lamina Inc
Publication of CA2336093A1 publication Critical patent/CA2336093A1/en
Application granted granted Critical
Publication of CA2336093C publication Critical patent/CA2336093C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • B01F29/63—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers with fixed bars, i.e. stationary, or fixed on the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75465—Discharge mechanisms characterised by the means for discharging the components from the mixer using suction, vacuum, e.g. with a pipette
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002336093A 1998-07-07 1999-07-07 Improved method for mixing and processing specimen samples Expired - Fee Related CA2336093C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9202998P 1998-07-07 1998-07-07
US60/092,029 1998-07-07
PCT/US1999/015281 WO2000002031A1 (en) 1998-07-07 1999-07-07 Improved method for mixing and processing specimen samples

Publications (2)

Publication Number Publication Date
CA2336093A1 CA2336093A1 (en) 2000-01-13
CA2336093C true CA2336093C (en) 2008-05-20

Family

ID=22230970

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002336093A Expired - Fee Related CA2336093C (en) 1998-07-07 1999-07-07 Improved method for mixing and processing specimen samples

Country Status (10)

Country Link
EP (1) EP1093572B1 (https=)
JP (1) JP2002519692A (https=)
KR (1) KR100886264B1 (https=)
CN (1) CN1136446C (https=)
AT (1) ATE228650T1 (https=)
AU (1) AU758047B2 (https=)
CA (1) CA2336093C (https=)
DE (1) DE69904179T2 (https=)
MX (1) MXPA01000222A (https=)
WO (1) WO2000002031A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0211963D0 (en) * 2002-05-24 2002-07-03 British American Tobacco Co An exposure device
FR2846548B1 (fr) 2002-11-04 2005-01-28 Sofradim Production Piece composite intermediaire pour faconnage de protheses de renfort
IE20030856A1 (en) * 2003-11-14 2005-06-15 Enfer Technology Ltd Sample homogeniser
EP1697723B1 (en) * 2003-12-08 2007-06-06 Blue I Water Technologies Ltd. A measuring cell
US8216528B2 (en) * 2005-09-29 2012-07-10 Sysmex Corporation Sample preparation kit, sample preparation container, and sample processing device
FR2955458B1 (fr) * 2010-01-27 2014-09-05 Novacyt Solution de fixation pour des cellules biologiques
KR101157027B1 (ko) 2011-01-05 2012-06-20 조윤희 배합기
GB2496597B (en) * 2011-11-14 2017-10-04 Bio-Check(Uk) Ltd Cartridge for containing a sample
CN104677674A (zh) * 2013-11-29 2015-06-03 武汉迪艾斯科技有限公司 可搅拌取样装置
CN106062170B (zh) * 2014-02-04 2019-11-05 瑞尔赛特股份有限公司 用于收集靶材料的仪器、系统和方法
CN104297033B (zh) * 2014-10-20 2017-03-29 浙江海洋学院 非水相液体土壤污染物浓度配制装置及方法
EP3600669A4 (en) * 2017-03-24 2020-12-23 Universal Biosensors, Pty. Ltd. DEVICES AND METHODS FOR PRE-TREATMENT OF SAMPLE
EP3620772B1 (en) * 2018-09-06 2021-10-13 Milestone S.r.l. System and method for filling a closed container with a fixative solution
WO2020117610A1 (en) * 2018-12-08 2020-06-11 Min Wei Apparatus for manufacturing cell therapy product
KR20210132085A (ko) 2019-02-18 2021-11-03 도요보 가부시키가이샤 2축 연신 폴리아미드 필름 및 적층 필름
GB2592430B (en) 2020-02-28 2022-12-21 Agilent Technologies Inc Sample injector with sample fluid filtering

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5000922A (en) * 1986-02-19 1991-03-19 Jon Turpen Sample filtration, separation and dispensing device
US4845025A (en) * 1987-11-10 1989-07-04 Coulter Corporation Biological sample mixing apparatus and method
US5301685A (en) * 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US5356814A (en) * 1992-09-29 1994-10-18 Hoffmann-La Roche Inc. Disaggregation device for cytological specimens
JPH08507995A (ja) * 1993-03-08 1996-08-27 ケイヴィエム・テクノロジィズ・インコーポレイテッド 液体サンプル容器

Also Published As

Publication number Publication date
ATE228650T1 (de) 2002-12-15
CN1136446C (zh) 2004-01-28
KR100886264B1 (ko) 2009-02-27
WO2000002031A1 (en) 2000-01-13
EP1093572A1 (en) 2001-04-25
DE69904179T2 (de) 2003-07-24
AU758047B2 (en) 2003-03-13
AU5090999A (en) 2000-01-24
EP1093572B1 (en) 2002-11-27
CA2336093A1 (en) 2000-01-13
WO2000002031A9 (en) 2000-04-06
DE69904179D1 (de) 2003-01-09
JP2002519692A (ja) 2002-07-02
MXPA01000222A (es) 2003-09-10
CN1316053A (zh) 2001-10-03
KR20010071768A (ko) 2001-07-31

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Effective date: 20150707