CA2330254C - Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale - Google Patents

Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale Download PDF

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Publication number
CA2330254C
CA2330254C CA002330254A CA2330254A CA2330254C CA 2330254 C CA2330254 C CA 2330254C CA 002330254 A CA002330254 A CA 002330254A CA 2330254 A CA2330254 A CA 2330254A CA 2330254 C CA2330254 C CA 2330254C
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Prior art keywords
complex
activity
mammal
sample
malnutrition
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Expired - Fee Related
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CA002330254A
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CA2330254A1 (fr
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Khursheed Jeejeebhoy
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Priority claimed from CA002240588A external-priority patent/CA2240588A1/fr
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Publication of CA2330254C publication Critical patent/CA2330254C/fr
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne, dans un premier aspect, un procédé de détection de la malnutrition chez un mammalien. Le procédé consiste: (a) à mesurer l'activité chez le mammalien d'un ou plusieurs complexes sélectionnés dans le groupe formé par le Complexe I, le Complexe II et le Complexe III; et (b) à déterminer si le niveau d'activité se trouve au-dessous du niveau d'activité des complexes dans un échantillon de contrôle normal. L'invention concerne, dans un deuxième aspect, l'utilisation du Complexe I pour effectuer une évaluation nutritionnelle d'un mammalien. L'invention concerne, dans un troisième aspect, l'utilisation du Complexe II pour effectuer une évaluation nutritionnelle d'un mammalien. L'invention concerne, dans un quatrième aspect, l'utilisation du Complexe III pour effectuer une évaluation nutritionnelle d'un mammalien. L'invention concerne, dans un cinquième aspect, une trousse d'évaluation nutritionnelle d'un mammalien, la trousse comprenant un ou plusieurs réactifs de mesure chez un mammalien de l'activité d'un ou de plusieurs complexes sélectionnés dans le groupe formé par le Complexe I, le Complexe II et le Complexe III.
CA002330254A 1998-06-12 1999-06-14 Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale Expired - Fee Related CA2330254C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002330254A CA2330254C (fr) 1998-06-12 1999-06-14 Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002240588A CA2240588A1 (fr) 1998-06-12 1998-06-12 Estimation nutritionnelle par l'activite complexe lymphocite mitochondriale
CA2,240,588 1998-06-12
PCT/CA1999/000551 WO1999066064A1 (fr) 1998-06-12 1999-06-14 Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale
CA002330254A CA2330254C (fr) 1998-06-12 1999-06-14 Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale

Publications (2)

Publication Number Publication Date
CA2330254A1 CA2330254A1 (fr) 1999-12-23
CA2330254C true CA2330254C (fr) 2009-06-23

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA002330254A Expired - Fee Related CA2330254C (fr) 1998-06-12 1999-06-14 Evaluation nutritionnelle par mesure de l'activite complexe mitochondriale

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CA (1) CA2330254C (fr)

Also Published As

Publication number Publication date
CA2330254A1 (fr) 1999-12-23

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