CA2319380A1 - Fragments d'acides nucleiques et fragments polypeptidiques derives de m. tuberculosis - Google Patents
Fragments d'acides nucleiques et fragments polypeptidiques derives de m. tuberculosis Download PDFInfo
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- CA2319380A1 CA2319380A1 CA002319380A CA2319380A CA2319380A1 CA 2319380 A1 CA2319380 A1 CA 2319380A1 CA 002319380 A CA002319380 A CA 002319380A CA 2319380 A CA2319380 A CA 2319380A CA 2319380 A1 CA2319380 A1 CA 2319380A1
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- polypeptide
- tuberculosis
- seq
- amino acid
- sequence
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La présente invention concerne l'identification et la caractérisation d'un certain nombre de nouvelles protéines et de fragments de protéines (Nos. ID séq.: 175, 177, 179, 181, 183 et 185) dérivés de M. tuberculosis. L'invention se rapporte à des polypeptides, à leurs fragments biologiquement actifs, aux gènes les codant et à des compositions immunologiques telles que les vaccins et les réactifs pour tests cutanés contenant ces polypeptides. Dans un autre aspect, l'invention concerne une découverte surprenante: on a découvert que CFP7A provoque une réponse immunitaire à degré élevé de protection.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK127797 | 1997-11-10 | ||
| DKPA199701277 | 1997-11-10 | ||
| US7048898P | 1998-01-05 | 1998-01-05 | |
| US60/070,488 | 1998-01-05 | ||
| PCT/DK1998/000132 WO1998044119A1 (fr) | 1997-04-02 | 1998-04-01 | FRAGMENTS D'ACIDE NUCLEIQUE ET FRAGMENTS POLYPEPTIDIQUES DERIVES DE $i(M. TUBERCULOSIS) |
| DKPCT/DK98/00132 | 1998-04-01 | ||
| PCT/DK1998/000438 WO1999024577A1 (fr) | 1997-11-10 | 1998-10-08 | Fragments d'acides nucleiques et fragments polypeptidiques derives de m. tuberculosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2319380A1 true CA2319380A1 (fr) | 1999-05-20 |
Family
ID=27221205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002319380A Abandoned CA2319380A1 (fr) | 1997-11-10 | 1998-10-08 | Fragments d'acides nucleiques et fragments polypeptidiques derives de m. tuberculosis |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1029053A1 (fr) |
| AU (1) | AU750173B2 (fr) |
| CA (1) | CA2319380A1 (fr) |
| NZ (1) | NZ504951A (fr) |
| WO (1) | WO1999024577A1 (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| CA2322505A1 (fr) * | 1998-03-06 | 1999-09-10 | Statens Serum Institut | Fabrication de polypeptides mycobacteriens par une bacterie d'acide lactique |
| GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| AU779495B2 (en) | 1999-07-13 | 2005-01-27 | Statens Serum Institut | Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family |
| US6537552B1 (en) | 1999-10-19 | 2003-03-25 | Iowa State University Research Foundation | Vaccine adjuvant |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| EP1278769A2 (fr) * | 2000-04-19 | 2003-01-29 | Statens Serum Institut | Antigenes de la tuberculose et procedes de leur utilisation |
| AU2001271963A1 (en) * | 2000-07-10 | 2002-01-21 | Colorado State University Research Foundation | Mid-life vaccine and methods for boosting anti-mycobacterial immunity |
| CA2689741C (fr) * | 2001-01-08 | 2013-10-01 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services, Centers For Disea | Modele de tuberculose humaine latente, antigenes diagnostiques et methodes d'utilisation associees |
| KR101255870B1 (ko) | 2004-11-16 | 2013-04-17 | 아에라스 글로벌 티비 백신 파운데이션 | 재조합 바이러스 벡터를 포함하는 다가 백신 |
| CN100354004C (zh) * | 2004-11-19 | 2007-12-12 | 李忠明 | 结核杆菌嵌合基因疫苗及其制备方法 |
| BRPI0708865A8 (pt) | 2006-03-14 | 2019-01-22 | Univ Oregon Health & Science | métodos para produzir uma resposta imune à tuberculose |
| GB0618127D0 (en) * | 2006-09-14 | 2006-10-25 | Isis Innovation | Biomarker |
| EP2087128A4 (fr) | 2006-11-01 | 2009-11-04 | Immport Therapeutics Inc | Composition et procédés pour des antigènes immunodominants |
| EP2361930A3 (fr) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimeres du complexes peptide-cmh et leur utilisation dans des maladies infectieuses de borrelia |
| EP3023436A1 (fr) | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Procédés améliorés pour produire, marquer et utiliser des multimères du cmh |
| WO2009039854A2 (fr) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Multimères cmh dans le diagnostic, le vaccin et le traitement de la tuberculose |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| WO2010037402A1 (fr) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Vaccins moléculaires contre les maladies infectieuses |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| EP2711706A1 (fr) | 2012-09-21 | 2014-03-26 | LIONEX Diagnostics and Therapeutics GmbH | Thiolperoxidase mycobactérienne et son utilisation |
| EP3155426B1 (fr) | 2014-06-13 | 2023-07-19 | Immudex ApS | Détection générale et isolement de cellules spécifiques par liaison de molécules marquées |
| CN104306408B (zh) * | 2014-10-31 | 2019-02-01 | 潘霞 | 一种治疗小儿湿疹的多糖核酸药物组合物 |
| CN104383162A (zh) * | 2014-11-21 | 2015-03-04 | 王正琦 | 一种用于婴儿湿疹的药膏 |
| CN106248934B (zh) * | 2016-08-25 | 2018-04-06 | 中国疾病预防控制中心传染病预防控制所 | 结核分枝杆菌抗原蛋白Rv0446c及其T细胞表位肽的应用 |
| MX2022013152A (es) * | 2020-04-20 | 2023-02-09 | Univ Saskatchewan | Composiciones y métodos para prevenir, controlar y diagnosticar infecciones por micobacterias. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK79893D0 (da) * | 1993-07-02 | 1993-07-02 | Statens Seruminstitut | New vaccine |
| AU6024596A (en) * | 1995-05-23 | 1996-12-11 | Regents Of The University Of California, The | Abundant extracellular products and methods for their production and use |
| ES2262595T3 (es) * | 1995-09-01 | 2006-12-01 | Corixa Corporation | Compuestos y metodos para la inmunoterapia y diagnostico de la tuberculosis. |
| MX9801687A (es) * | 1995-09-01 | 1998-11-29 | Corixa Corp | Compuestos y metodos para el diagnostico de tuberculosis. |
| CA2285625C (fr) * | 1997-04-02 | 2015-06-30 | Statens Serum Institut | Fragments d'acide nucleique et fragments polypeptidiques derives de m. tuberculosis |
| US6613881B1 (en) * | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
| US6555653B2 (en) * | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
-
1998
- 1998-10-08 AU AU94338/98A patent/AU750173B2/en not_active Expired
- 1998-10-08 CA CA002319380A patent/CA2319380A1/fr not_active Abandoned
- 1998-10-08 WO PCT/DK1998/000438 patent/WO1999024577A1/fr not_active Application Discontinuation
- 1998-10-08 NZ NZ504951A patent/NZ504951A/en not_active IP Right Cessation
- 1998-10-08 EP EP98947412A patent/EP1029053A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999024577A1 (fr) | 1999-05-20 |
| EP1029053A1 (fr) | 2000-08-23 |
| AU9433898A (en) | 1999-05-31 |
| AU750173B2 (en) | 2002-07-11 |
| NZ504951A (en) | 2001-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |