CA2300806A1 - Dexamethasone gel - Google Patents
Dexamethasone gel Download PDFInfo
- Publication number
- CA2300806A1 CA2300806A1 CA002300806A CA2300806A CA2300806A1 CA 2300806 A1 CA2300806 A1 CA 2300806A1 CA 002300806 A CA002300806 A CA 002300806A CA 2300806 A CA2300806 A CA 2300806A CA 2300806 A1 CA2300806 A1 CA 2300806A1
- Authority
- CA
- Canada
- Prior art keywords
- gel
- dexamethasone
- preparation
- dexamethasone gel
- viscosity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
The invention relates to an ophthalmological preparation containing dexamethasone dihydrogenphosphate disodium as the active ingredient and, optionally, also containing the usual additives and water, which is characterized by a content of at least one gel-forming pharmacologically acceptable substance in a quantity sufficient for adjusting the viscosity of the preparation as a gel.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19744113.0 | 1997-10-06 | ||
DE19744113A DE19744113A1 (en) | 1997-10-06 | 1997-10-06 | Ophthalmological dexamethasone preparation |
PCT/EP1998/006339 WO1999017780A1 (en) | 1997-10-06 | 1998-10-05 | Dexamethasone gel |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2300806A1 true CA2300806A1 (en) | 1999-04-15 |
CA2300806C CA2300806C (en) | 2004-02-03 |
Family
ID=7844743
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002300806A Expired - Lifetime CA2300806C (en) | 1997-10-06 | 1998-10-05 | Dexamethasone gel |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1021192B1 (en) |
JP (1) | JP4156793B2 (en) |
KR (1) | KR100392481B1 (en) |
CN (1) | CN1142782C (en) |
AR (1) | AR017170A1 (en) |
AT (1) | ATE230601T1 (en) |
BR (1) | BR9812849A (en) |
CA (1) | CA2300806C (en) |
DE (2) | DE19744113A1 (en) |
DK (1) | DK1021192T3 (en) |
ES (1) | ES2191352T3 (en) |
HK (1) | HK1030748A1 (en) |
HU (1) | HU224986B1 (en) |
IL (1) | IL135001A0 (en) |
MX (1) | MXPA00003363A (en) |
PL (1) | PL189727B1 (en) |
WO (1) | WO1999017780A1 (en) |
ZA (1) | ZA989066B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200808375A (en) | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
CN101190177B (en) * | 2006-11-24 | 2010-09-01 | 上海医药工业研究院 | Dectancyl partial film forming gel composition and uses thereof |
US20150190407A1 (en) * | 2014-01-07 | 2015-07-09 | Insite Vision Incorporated | Methods for treatment of postoperative inflammation with reduced intraocular pressure |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2212392C3 (en) * | 1972-03-15 | 1981-03-19 | Avicon Inc., Fort Worth, Tex. | Use of microcrystalline collagen for the manufacture of an aqueous pharmaceutical composition for topical application to the eye |
JPS6056684B2 (en) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | eye drops |
US4271143A (en) * | 1978-01-25 | 1981-06-02 | Alcon Laboratories, Inc. | Sustained release ophthalmic drug dosage |
ATE6466T1 (en) * | 1979-10-26 | 1984-03-15 | Smith And Nephew Associated Companies P.L.C. | AUTOCLAVABLE EMULSIONS. |
JPS63174924A (en) * | 1987-01-14 | 1988-07-19 | Toko Yakuhin Kogyo Kk | Ointment base and ointment |
US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
EP0551626A1 (en) * | 1991-12-19 | 1993-07-21 | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. | Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation |
WO1993017664A1 (en) * | 1992-03-02 | 1993-09-16 | Alcon Laboratories, Inc. | Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions |
DE4209722C3 (en) * | 1992-03-25 | 1997-06-19 | Medproject Pharma Entwicklungs | Dripable gel for ophthalmology |
WO1995005803A1 (en) * | 1993-08-20 | 1995-03-02 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
DE4404990C1 (en) * | 1994-02-17 | 1995-05-04 | Mann Gerhard Chem Pharm Fab | Process for producing a sterile prednisolone gel |
US5683993A (en) * | 1995-06-22 | 1997-11-04 | Ciba Vision Corporation | Compositions and methods for stabilizing polymers |
DE19614823A1 (en) * | 1996-04-15 | 1997-10-16 | Mann Gerhard Chem Pharm Fab | Ophthalmic composition with prolonged retention time on the eye |
-
1997
- 1997-10-06 DE DE19744113A patent/DE19744113A1/en not_active Withdrawn
-
1998
- 1998-10-05 WO PCT/EP1998/006339 patent/WO1999017780A1/en active IP Right Grant
- 1998-10-05 DE DE59806884T patent/DE59806884D1/en not_active Expired - Lifetime
- 1998-10-05 DK DK98954349T patent/DK1021192T3/en active
- 1998-10-05 ES ES98954349T patent/ES2191352T3/en not_active Expired - Lifetime
- 1998-10-05 BR BR9812849-3A patent/BR9812849A/en active Search and Examination
- 1998-10-05 CA CA002300806A patent/CA2300806C/en not_active Expired - Lifetime
- 1998-10-05 CN CNB988081091A patent/CN1142782C/en not_active Expired - Lifetime
- 1998-10-05 ZA ZA989066A patent/ZA989066B/en unknown
- 1998-10-05 EP EP98954349A patent/EP1021192B1/en not_active Expired - Lifetime
- 1998-10-05 AT AT98954349T patent/ATE230601T1/en active
- 1998-10-05 KR KR10-2000-7003665A patent/KR100392481B1/en active IP Right Grant
- 1998-10-05 AR ARP980104965A patent/AR017170A1/en active IP Right Grant
- 1998-10-05 JP JP2000514651A patent/JP4156793B2/en not_active Expired - Lifetime
- 1998-10-05 IL IL13500198A patent/IL135001A0/en not_active IP Right Cessation
- 1998-10-05 MX MXPA00003363A patent/MXPA00003363A/en active IP Right Grant
- 1998-10-05 HU HU0003796A patent/HU224986B1/en unknown
- 1998-10-05 PL PL98341026A patent/PL189727B1/en unknown
-
2001
- 2001-03-08 HK HK01101674A patent/HK1030748A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK1021192T3 (en) | 2003-05-05 |
ATE230601T1 (en) | 2003-01-15 |
DE59806884D1 (en) | 2003-02-13 |
DE19744113A1 (en) | 1999-04-15 |
JP4156793B2 (en) | 2008-09-24 |
KR100392481B1 (en) | 2003-07-23 |
HUP0003796A2 (en) | 2001-04-28 |
IL135001A0 (en) | 2001-05-20 |
HUP0003796A3 (en) | 2001-05-28 |
HK1030748A1 (en) | 2001-05-18 |
JP2001518510A (en) | 2001-10-16 |
WO1999017780A1 (en) | 1999-04-15 |
PL189727B1 (en) | 2005-09-30 |
PL341026A1 (en) | 2001-03-26 |
EP1021192B1 (en) | 2003-01-08 |
WO1999017780A8 (en) | 2000-01-27 |
EP1021192A1 (en) | 2000-07-26 |
ES2191352T3 (en) | 2003-09-01 |
KR20010030939A (en) | 2001-04-16 |
MXPA00003363A (en) | 2007-12-07 |
CN1266369A (en) | 2000-09-13 |
ZA989066B (en) | 1999-06-15 |
BR9812849A (en) | 2000-08-08 |
HU224986B1 (en) | 2006-05-29 |
CN1142782C (en) | 2004-03-24 |
CA2300806C (en) | 2004-02-03 |
AR017170A1 (en) | 2001-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20181005 |