CA2297673A1 - Pharmaceutical compositions containing an effervescent acid-base couple - Google Patents
Pharmaceutical compositions containing an effervescent acid-base couple Download PDFInfo
- Publication number
- CA2297673A1 CA2297673A1 CA002297673A CA2297673A CA2297673A1 CA 2297673 A1 CA2297673 A1 CA 2297673A1 CA 002297673 A CA002297673 A CA 002297673A CA 2297673 A CA2297673 A CA 2297673A CA 2297673 A1 CA2297673 A1 CA 2297673A1
- Authority
- CA
- Canada
- Prior art keywords
- effervescent
- pharmaceutical compositions
- compositions containing
- effervescent acid
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000007907 direct compression Methods 0.000 abstract 1
- RRPFCKLVOUENJB-UHFFFAOYSA-L disodium;2-aminoacetic acid;carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O.NCC(O)=O RRPFCKLVOUENJB-UHFFFAOYSA-L 0.000 abstract 1
- 239000007938 effervescent tablet Substances 0.000 abstract 1
- 239000001530 fumaric acid Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- 239000011976 maleic acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
A pharmaceutical composition in form of effervescent tablets comprising an active ingredient and an effervescent blend, wherein the effervescent blend comprises an acidic component and sodium glycine carbonate as alkaline components. Preferred acid component are fumaric acid, maleic acid and their salts. Tablets are prepared by direct compression in normal thermo-hygrometric conditions and with standard tabletting equipment.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI97A001746 | 1997-07-23 | ||
| ITMA971746 | 1997-07-23 | ||
| PCT/EP1998/004517 WO1999004765A2 (en) | 1997-07-23 | 1998-07-23 | Pharmaceutical compositions containing an effervescent acid-base couple |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2297673A1 true CA2297673A1 (en) | 1999-02-04 |
| CA2297673C CA2297673C (en) | 2008-02-12 |
Family
ID=31726532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002297673A Expired - Fee Related CA2297673C (en) | 1997-07-23 | 1998-07-23 | Pharmaceutical compositions containing an effervescent acid-base couple |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2297673C (en) |
-
1998
- 1998-07-23 CA CA002297673A patent/CA2297673C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2297673C (en) | 2008-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20140723 |