CA2290502A1 - Treatment of hepatic cirrhosis - Google Patents

Treatment of hepatic cirrhosis Download PDF

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Publication number
CA2290502A1
CA2290502A1 CA002290502A CA2290502A CA2290502A1 CA 2290502 A1 CA2290502 A1 CA 2290502A1 CA 002290502 A CA002290502 A CA 002290502A CA 2290502 A CA2290502 A CA 2290502A CA 2290502 A1 CA2290502 A1 CA 2290502A1
Authority
CA
Canada
Prior art keywords
treatment
hepatic cirrhosis
composition
hepatic
cirrhosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002290502A
Other languages
French (fr)
Other versions
CA2290502C (en
Inventor
Mark Pines
Arnon Nagler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Agricultural Research Organization of Israel Ministry of Agriculture
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25338371&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2290502(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2290502A1 publication Critical patent/CA2290502A1/en
Application granted granted Critical
Publication of CA2290502C publication Critical patent/CA2290502C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A composition for treating hepatic fibrosis and hepatic cirrhosis, and methods of using and manufacturing the composition are provided. The composition includes a quinazolinone derivative, preferably Halofuginone.
CA002290502A 1997-05-23 1998-05-22 Treatment of hepatic cirrhosis Expired - Fee Related CA2290502C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86238297A 1997-05-23 1997-05-23
US08/862,382 1997-05-23
PCT/US1998/010505 WO1998052514A2 (en) 1997-05-23 1998-05-22 Treatment of hepatic cirrhosis

Publications (2)

Publication Number Publication Date
CA2290502A1 true CA2290502A1 (en) 1998-11-26
CA2290502C CA2290502C (en) 2007-08-28

Family

ID=25338371

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002290502A Expired - Fee Related CA2290502C (en) 1997-05-23 1998-05-22 Treatment of hepatic cirrhosis

Country Status (8)

Country Link
EP (1) EP1014988A2 (en)
JP (1) JP2002515905A (en)
KR (1) KR100540537B1 (en)
CN (1) CN1160073C (en)
AU (1) AU748754B2 (en)
CA (1) CA2290502C (en)
IL (1) IL132848A (en)
WO (1) WO1998052514A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006504769A (en) * 2002-10-31 2006-02-09 ステート オブ イスラエル、ミニストリー オブ アグリカルチャー Quinazolinone compositions for controlling gene expression for pathological processes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320124A (en) * 1964-07-20 1967-05-16 American Cyanamid Co Method for treating coccidiosis with quinazolinones
CA2113229C (en) * 1994-01-11 1999-04-20 Mark Pines Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof

Also Published As

Publication number Publication date
AU7692298A (en) 1998-12-11
CN1265034A (en) 2000-08-30
CN1160073C (en) 2004-08-04
CA2290502C (en) 2007-08-28
AU748754B2 (en) 2002-06-13
WO1998052514A3 (en) 1999-08-19
JP2002515905A (en) 2002-05-28
KR20010012838A (en) 2001-02-26
EP1014988A2 (en) 2000-07-05
IL132848A0 (en) 2001-03-19
WO1998052514A2 (en) 1998-11-26
IL132848A (en) 2004-08-31
KR100540537B1 (en) 2006-01-10

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Legal Events

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EEER Examination request
MKLA Lapsed