CA2282705A1 - Procedes d'analyse d'un acide nucleique - Google Patents

Procedes d'analyse d'un acide nucleique Download PDF

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Publication number
CA2282705A1
CA2282705A1 CA002282705A CA2282705A CA2282705A1 CA 2282705 A1 CA2282705 A1 CA 2282705A1 CA 002282705 A CA002282705 A CA 002282705A CA 2282705 A CA2282705 A CA 2282705A CA 2282705 A1 CA2282705 A1 CA 2282705A1
Authority
CA
Canada
Prior art keywords
probe
nucleic acid
sample
nucleotide
probes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002282705A
Other languages
English (en)
Inventor
Anthony P. Shuber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Exact Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Laboratories Inc filed Critical Exact Laboratories Inc
Publication of CA2282705A1 publication Critical patent/CA2282705A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des procédés de détection de la présence, dans un échantillon biologique, de séquences mutantes dans une sous-population de séquences géniques. Lesdits procédés sont utiles, en particulier, pour identifier des individus porteurs d'un indicateur de mutation génique du cancer colectoral primaire.
CA002282705A 1997-02-28 1998-02-27 Procedes d'analyse d'un acide nucleique Abandoned CA2282705A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3913397P 1997-02-28 1997-02-28
US60/039,133 1997-02-28
US81557697A 1997-03-12 1997-03-12
US08/815,576 1997-03-12
PCT/US1998/004003 WO1998038338A1 (fr) 1997-02-28 1998-02-27 Procedes d'analyse d'un acide nucleique

Publications (1)

Publication Number Publication Date
CA2282705A1 true CA2282705A1 (fr) 1998-09-03

Family

ID=26715843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002282705A Abandoned CA2282705A1 (fr) 1997-02-28 1998-02-27 Procedes d'analyse d'un acide nucleique

Country Status (4)

Country Link
EP (1) EP0975797A1 (fr)
AU (1) AU6676898A (fr)
CA (1) CA2282705A1 (fr)
WO (1) WO1998038338A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US20020001800A1 (en) * 1998-08-14 2002-01-03 Stanley N. Lapidus Diagnostic methods using serial testing of polymorphic loci
US20030044780A1 (en) * 1998-11-23 2003-03-06 Stanley N. Lapidus Primer extension methods utilizing donor and acceptor molecules for detecting nucleic acids
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
AU3269401A (en) * 1999-11-15 2001-05-30 Qiagen Genomics, Inc. Simultaneous hybridization/priming for snp analysis
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP1903117A1 (fr) * 2006-09-22 2008-03-26 Veterinärmedizinische Universität Wien Méthodes pour la détection de mutations au moyen d' amorces qui hybrident de façon contigue

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883750A (en) * 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
ES2101116T3 (es) * 1991-09-13 1997-07-01 Cytocell Ltd Metodo de deteccion de una secuencia de acidos nucleicos.

Also Published As

Publication number Publication date
EP0975797A1 (fr) 2000-02-02
WO1998038338A1 (fr) 1998-09-03
AU6676898A (en) 1998-09-18

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Legal Events

Date Code Title Description
FZDE Discontinued