CA2277724A1 - A composition for inducing humoral anergy to an immunogen - Google Patents
A composition for inducing humoral anergy to an immunogen Download PDFInfo
- Publication number
- CA2277724A1 CA2277724A1 CA002277724A CA2277724A CA2277724A1 CA 2277724 A1 CA2277724 A1 CA 2277724A1 CA 002277724 A CA002277724 A CA 002277724A CA 2277724 A CA2277724 A CA 2277724A CA 2277724 A1 CA2277724 A1 CA 2277724A1
- Authority
- CA
- Canada
- Prior art keywords
- immunogen
- composition
- inducing humoral
- immunogens
- conjugates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Conjugates of stable nonimmunogenic polymers and analogs of immunogens that possess the specific B cell binding ability of the immunogen but lack T cell epitopes and which, when introduced into individuals, induce humoral anergy to the immunogen are disclosed. Accordingly, these conjugates are useful for treating antibody-mediated pathologies that are caused by foreign or self immunogens.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US652,648 | 1991-02-08 | ||
US07/652,648 US5268454A (en) | 1991-02-08 | 1991-02-08 | Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier |
CA002076648A CA2076648C (en) | 1991-02-08 | 1992-02-04 | Composition for inducing humoral anergy to an immunogen |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002076648A Division CA2076648C (en) | 1991-02-08 | 1992-02-04 | Composition for inducing humoral anergy to an immunogen |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2277724A1 true CA2277724A1 (en) | 1992-08-09 |
CA2277724C CA2277724C (en) | 2003-05-27 |
Family
ID=25675458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002277724A Expired - Fee Related CA2277724C (en) | 1991-02-08 | 1992-02-04 | A composition for inducing humoral anergy to an immunogen |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2277724C (en) |
-
1992
- 1992-02-04 CA CA002277724A patent/CA2277724C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2277724C (en) | 2003-05-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |