CA2270776A1 - Radially expandable stent - Google Patents
Radially expandable stent Download PDFInfo
- Publication number
- CA2270776A1 CA2270776A1 CA002270776A CA2270776A CA2270776A1 CA 2270776 A1 CA2270776 A1 CA 2270776A1 CA 002270776 A CA002270776 A CA 002270776A CA 2270776 A CA2270776 A CA 2270776A CA 2270776 A1 CA2270776 A1 CA 2270776A1
- Authority
- CA
- Canada
- Prior art keywords
- radially expandable
- expandable stent
- self
- stent
- stent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/061—Blood vessels provided with means for allowing access to secondary lumens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0019—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
Landscapes
- Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
A self-expanding stent for implanting in a body vessel, in particular in the carotid, whereby the stent has a sheathing made from an irreversibly expandable material which prevents the self-expansion of the hollow cylindrical element.
Description
Radially Expandable Stent D a s c r i p t i o n The invention concerns a radially expandable stent for implanting in a body vessel, in particular in the carotid, in the form of a self-expanding hollow cylindrical element.
The purpose of stents in blood vessels is to prevent a renewed narrowing or a renewed occlusion of the blood vessels after a dilatation, in order to again ensure a good blood flow. In addition to this purpose, stents in the carotids also have the function of preventing deposits on the blood vessels from becoming separating and being flushed into the brain vessels so that the patient does not suffer a stroke or other permanent damage.
Conventional stents composed of a cell or mesh structure are only capable of holding back deposits to a limited degree. If these deposits separate in the carotids, they are flushed into the brain with the blood flow and can here. result in the blockage of vessels. A blockage in the blood supply usually induces brain damage in the form of a stroke and should, therefore, be avoided in any case.
Stents are implanted in blood vessels to reduce or prevent the possibility of renewed narrowing. Furthermore, so-called stent grafts are implanted to bridge defects such as aneurisms, ruptures, dissections, punctures, etc. or to enable sealing of the altered or diseased material.
Stent grafts are stents which are covered with a biocompatible
The purpose of stents in blood vessels is to prevent a renewed narrowing or a renewed occlusion of the blood vessels after a dilatation, in order to again ensure a good blood flow. In addition to this purpose, stents in the carotids also have the function of preventing deposits on the blood vessels from becoming separating and being flushed into the brain vessels so that the patient does not suffer a stroke or other permanent damage.
Conventional stents composed of a cell or mesh structure are only capable of holding back deposits to a limited degree. If these deposits separate in the carotids, they are flushed into the brain with the blood flow and can here. result in the blockage of vessels. A blockage in the blood supply usually induces brain damage in the form of a stroke and should, therefore, be avoided in any case.
Stents are implanted in blood vessels to reduce or prevent the possibility of renewed narrowing. Furthermore, so-called stent grafts are implanted to bridge defects such as aneurisms, ruptures, dissections, punctures, etc. or to enable sealing of the altered or diseased material.
Stent grafts are stents which are covered with a biocompatible
- 2 -material impermeable to blood or particles that separate from the vascular wall and can be swept into the blood stream.
In stent grafts, a difference is made between balloon expandable and self-expanding systems. Balloon expandable systems are distinguished therein that they can be accurately adapted to the diameter of the vessel. With this system, it is possible to make allowance for the narrowing of a vessel.
Self-expanding stent grafts are composed of either plaited, woven or knitted flexible materials or a self-expandable material such as e.g. NITINOL is used. The sheathing consists for the most part of PETP (dacron) or PTFE (teflon).
Depending on the process, PTFE is distinguished thereby that it can expand in a direction without this resulting in restoring forces. In particular in balloon expandable systems, it is possible to expand the stent to the desired dimension and to adapt it accurately to the diameter of the vessel.
If necessary, it is also possible to subsequently expand such a stem, perhaps with a balloon, after it has been implanted.
Stent grafts that are covered with a PETP fabric can only be expanded to that dimension at which the fabric is stretched.
Therefore, the dimension of the vessel to be treated must first be accurately determined. It is only possible to adapt the stent graft to the anatomy of the vessel to a limited extent.
Self-expanding systems are distinguished by the special feature that they spring back to their original position when compressed from the outside.
i 'CA 02270776 1999-O5-04
In stent grafts, a difference is made between balloon expandable and self-expanding systems. Balloon expandable systems are distinguished therein that they can be accurately adapted to the diameter of the vessel. With this system, it is possible to make allowance for the narrowing of a vessel.
Self-expanding stent grafts are composed of either plaited, woven or knitted flexible materials or a self-expandable material such as e.g. NITINOL is used. The sheathing consists for the most part of PETP (dacron) or PTFE (teflon).
Depending on the process, PTFE is distinguished thereby that it can expand in a direction without this resulting in restoring forces. In particular in balloon expandable systems, it is possible to expand the stent to the desired dimension and to adapt it accurately to the diameter of the vessel.
If necessary, it is also possible to subsequently expand such a stem, perhaps with a balloon, after it has been implanted.
Stent grafts that are covered with a PETP fabric can only be expanded to that dimension at which the fabric is stretched.
Therefore, the dimension of the vessel to be treated must first be accurately determined. It is only possible to adapt the stent graft to the anatomy of the vessel to a limited extent.
Self-expanding systems are distinguished by the special feature that they spring back to their original position when compressed from the outside.
i 'CA 02270776 1999-O5-04
- 3 -Self-expanding, flexible systems are preferably used, especially in vessels which can be detected by touch from the outside or deformed by adjacent muscles.
The object of the invention is to improve a radially expandable stent such that it not only holds blood vessels in the expanded state but that it also prevents deposits on blood vessels from separating and being flushed into the brain vessels.
The object is solved by a stent having the features of claim 1.
The invention is distinguished thereby that a self-expanding stent is covered with a material, for example, PTFE, in such a way that the force of the self-expansion is not sufficient to expand the sheathing. Similar to a conventional balloon-expandable stent, this stent must be expanded by a balloon.
The special feature of the invention is that, in contrast to a balloon-expanding system, this system springs back into its original position if it is deformed by an external force.
However, at the same time, it is possible to use the advantage of balloon expanding systems and to accurately adapt the stent graft to the anatomy of the vessel.
As already described above, one of the advantages of stent grafts is that it is possible to fix deposits on the vascular wall with these systems and to prevent them from reaching into the blood stream.
A balloon expandable stent having an outer irreversible, expandable sheathing which, in addition, has flexible
The object of the invention is to improve a radially expandable stent such that it not only holds blood vessels in the expanded state but that it also prevents deposits on blood vessels from separating and being flushed into the brain vessels.
The object is solved by a stent having the features of claim 1.
The invention is distinguished thereby that a self-expanding stent is covered with a material, for example, PTFE, in such a way that the force of the self-expansion is not sufficient to expand the sheathing. Similar to a conventional balloon-expandable stent, this stent must be expanded by a balloon.
The special feature of the invention is that, in contrast to a balloon-expanding system, this system springs back into its original position if it is deformed by an external force.
However, at the same time, it is possible to use the advantage of balloon expanding systems and to accurately adapt the stent graft to the anatomy of the vessel.
As already described above, one of the advantages of stent grafts is that it is possible to fix deposits on the vascular wall with these systems and to prevent them from reaching into the blood stream.
A balloon expandable stent having an outer irreversible, expandable sheathing which, in addition, has flexible
- 4 -properties, is suitable especially for use in vessels that have different diameters over the length of the stenting. The diameter of vessels may differ by two or more millimeters such as, for example, the transition of the carotis communa into the carotis interns or externs.
Current self-expanding systems are not capable of appropriately sheathing these greatly varying diameters. In self-expanding stents, the stent must either be selected so large that a good fit to the wall is ensured or the stent is suitably selected for the smaller vessel.
In the first case, the stent exerts a continuous pressure on the vascular wall of the smaller vessel which can result therein that this vessel expands in the course of time and adapts to the geometry of the stent. In any event, this effect is undesirable.
If a self-expanding stent is selected so as to be suitable for the smaller vessel, then there is the danger that the stent does not clearly adjoin the wall in the larger vessel or in the area in which the vessel has a larger diameter. In particular in stent grafts, there is the possibility that areas are produced between the stent graft and vascular wall in which blood clots are formed by turbulances, which are to be avoided in any event.
The invention described offers the possibility of springing back to the set diameter by means of the flexible properties of the stent material when there is a possible compression.
At the same time, this system guarantees the possibility of perfectly adapting the stent to the anatomy of the vessel by using different balloon diameters.
Current self-expanding systems are not capable of appropriately sheathing these greatly varying diameters. In self-expanding stents, the stent must either be selected so large that a good fit to the wall is ensured or the stent is suitably selected for the smaller vessel.
In the first case, the stent exerts a continuous pressure on the vascular wall of the smaller vessel which can result therein that this vessel expands in the course of time and adapts to the geometry of the stent. In any event, this effect is undesirable.
If a self-expanding stent is selected so as to be suitable for the smaller vessel, then there is the danger that the stent does not clearly adjoin the wall in the larger vessel or in the area in which the vessel has a larger diameter. In particular in stent grafts, there is the possibility that areas are produced between the stent graft and vascular wall in which blood clots are formed by turbulances, which are to be avoided in any event.
The invention described offers the possibility of springing back to the set diameter by means of the flexible properties of the stent material when there is a possible compression.
At the same time, this system guarantees the possibility of perfectly adapting the stent to the anatomy of the vessel by using different balloon diameters.
- 5 -If a stent covered with an expandable material is to be inserted in a vascular branching, then the stent can at least have a radial opening which can be positioned in the vascular system in such a way that a corresponding side branch is not blocked. In the area of this opening, the sheathing has an opening which is preferably circular after the expansion in order not to affect the blood stream in the side branch.
Further embodiments of the stent can, if required, have several radial openings over the length of the stmt.
The sheathing can consist of an expandable PTFE. Stents having a sheathing of expandable PTFE are inexpensive to manufacture. Due to the good compatibility with the patients tissue, the sheathing can also consist of a homologous material. Sheathings made of an animal material, in particular of pig, beef or horse veins, are also relatively compatible with human tissue. The self-expandable material of the hollow cylindrical element can be a nickel/titanium alloy (NITINOL), a spring steel or a polymer material.
Further embodiments of the stent can, if required, have several radial openings over the length of the stmt.
The sheathing can consist of an expandable PTFE. Stents having a sheathing of expandable PTFE are inexpensive to manufacture. Due to the good compatibility with the patients tissue, the sheathing can also consist of a homologous material. Sheathings made of an animal material, in particular of pig, beef or horse veins, are also relatively compatible with human tissue. The self-expandable material of the hollow cylindrical element can be a nickel/titanium alloy (NITINOL), a spring steel or a polymer material.
Claims (10)
1. Radially expandable stent for implanting in a body vessel in the form of a self-expanding hollow cylindrical element, characterized therein that the stent has a sheathing made from an irreversibly expandable material which prevents the self-expansion of the hollow cylindrical element.
2. A radially expandable stent according to claim 1, characterized therein that it has at least one radial opening.
3. A radially expandable stent according to one of the claims 1 or 2, characterized therein that it can be further expanded beyond its expanded state, for example, by means of a balloon catheter.
4. A radially expandable stent according to one of the claims 1 to 3, characterized therein that the sheathing consists of an expandable PTFE.
5. A radially expandable stent according to one of the claims 1 to 4, characterized therein that the sheathing consists of a homologous material.
6. A radially expandable stem according to one of the claims 1 to 5, characterized therein that the sheathing consists of an animal material.
7. A radially expandable stent according to one of the claims 1 to 6, characterized therein that the sheathing consists of pig, beef or horse veins.
8. A radially expandable stent according to one of the claims 1 to 7, characterized therein that the self-expanding material is a nickel/titanium alloy.
9. A radially expandable stent according to one of the claims 1 to 7, characterized therein that the self-expanding material is a spring steel.
10. A radially expandable stent according to one of the claims 1 to 7, characterized therein that the self-expanding material is a polymer material.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19819629A DE19819629A1 (en) | 1998-05-04 | 1998-05-04 | Radially expandable stent |
| DE19819629.6 | 1998-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2270776A1 true CA2270776A1 (en) | 1999-11-04 |
Family
ID=7866477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002270776A Abandoned CA2270776A1 (en) | 1998-05-04 | 1999-05-04 | Radially expandable stent |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0955017B1 (en) |
| JP (1) | JP2000000311A (en) |
| AT (1) | ATE328552T1 (en) |
| CA (1) | CA2270776A1 (en) |
| DE (2) | DE19819629A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6196230B1 (en) | 1998-09-10 | 2001-03-06 | Percardia, Inc. | Stent delivery system and method of use |
| US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
| US6641610B2 (en) | 1998-09-10 | 2003-11-04 | Percardia, Inc. | Valve designs for left ventricular conduits |
| US6336937B1 (en) * | 1998-12-09 | 2002-01-08 | Gore Enterprise Holdings, Inc. | Multi-stage expandable stent-graft |
| SE514718C2 (en) | 1999-06-29 | 2001-04-09 | Jan Otto Solem | Apparatus for treating defective closure of the mitral valve apparatus |
| US6638237B1 (en) | 1999-08-04 | 2003-10-28 | Percardia, Inc. | Left ventricular conduits and methods for delivery |
| US6605053B1 (en) | 1999-09-10 | 2003-08-12 | Percardia, Inc. | Conduit designs and related methods for optimal flow control |
| US20050255230A1 (en) * | 2004-05-17 | 2005-11-17 | Clerc Claude O | Method of manufacturing a covered stent |
| WO2007021893A1 (en) * | 2005-08-12 | 2007-02-22 | Edwards Lifesciences Corporation | Medical implant with reinforcement mechanism |
| US7637946B2 (en) | 2006-02-09 | 2009-12-29 | Edwards Lifesciences Corporation | Coiled implant for mitral valve repair |
| CA3133857A1 (en) | 2019-03-20 | 2020-09-24 | inQB8 Medical Technologies, LLC | Aortic dissection implant |
| CN114504413B (en) * | 2022-01-19 | 2023-08-15 | 四川大学华西医院 | Implantable medical device and implantable medical device kit |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405377A (en) * | 1992-02-21 | 1995-04-11 | Endotech Ltd. | Intraluminal stent |
| DE9390115U1 (en) * | 1992-05-08 | 1994-12-22 | Schneider Usa Inc | Esophageal stent and delivery instrument |
| US5735892A (en) * | 1993-08-18 | 1998-04-07 | W. L. Gore & Associates, Inc. | Intraluminal stent graft |
| US5683451A (en) * | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
| US5788626A (en) * | 1995-11-21 | 1998-08-04 | Schneider (Usa) Inc | Method of making a stent-graft covered with expanded polytetrafluoroethylene |
-
1998
- 1998-05-04 DE DE19819629A patent/DE19819629A1/en not_active Ceased
-
1999
- 1999-04-22 EP EP99107942A patent/EP0955017B1/en not_active Expired - Lifetime
- 1999-04-22 DE DE59913501T patent/DE59913501D1/en not_active Expired - Lifetime
- 1999-04-22 AT AT99107942T patent/ATE328552T1/en not_active IP Right Cessation
- 1999-04-28 JP JP15844999A patent/JP2000000311A/en active Pending
- 1999-05-04 CA CA002270776A patent/CA2270776A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE19819629A1 (en) | 1999-11-11 |
| EP0955017A2 (en) | 1999-11-10 |
| EP0955017B1 (en) | 2006-06-07 |
| EP0955017A3 (en) | 1999-12-01 |
| ATE328552T1 (en) | 2006-06-15 |
| DE59913501D1 (en) | 2006-07-20 |
| JP2000000311A (en) | 2000-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |