CA2265198A1 - Method of producing a nicotine medicament and a medicament made by the method - Google Patents

Method of producing a nicotine medicament and a medicament made by the method Download PDF

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Publication number
CA2265198A1
CA2265198A1 CA002265198A CA2265198A CA2265198A1 CA 2265198 A1 CA2265198 A1 CA 2265198A1 CA 002265198 A CA002265198 A CA 002265198A CA 2265198 A CA2265198 A CA 2265198A CA 2265198 A1 CA2265198 A1 CA 2265198A1
Authority
CA
Canada
Prior art keywords
nicotine
medicament
producing
flowable mixture
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002265198A
Other languages
French (fr)
Other versions
CA2265198C (en
Inventor
Hanna Piskorz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sansa Corp Barbados Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002231968A external-priority patent/CA2231968A1/en
Application filed by Individual filed Critical Individual
Priority to CA002265198A priority Critical patent/CA2265198C/en
Publication of CA2265198A1 publication Critical patent/CA2265198A1/en
Application granted granted Critical
Publication of CA2265198C publication Critical patent/CA2265198C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method of producing a nicotine medicament for use in an inhaler comprises combining a nicotine formulation, a sugar and a liquid carrier including water to produce a flowable mixture and drying the flowable mixture at conditions to produce particles of the nicotine medicament suitable for delivery to the alveoli and lower airways of the person. Also disclosed is a nicotine medicament made by the method. The nicotine composition produced by this method is a composite particle suitable for tobacco replacement or withdrawal therapy.
CA002265198A 1998-03-11 1999-03-10 Method of producing a nicotine medicament and a medicament made by the method Expired - Lifetime CA2265198C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002265198A CA2265198C (en) 1998-03-11 1999-03-10 Method of producing a nicotine medicament and a medicament made by the method

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2,231,968 1998-03-11
CA002231968A CA2231968A1 (en) 1998-03-11 1998-03-11 Method of producing a nicotine medicament
CA002265198A CA2265198C (en) 1998-03-11 1999-03-10 Method of producing a nicotine medicament and a medicament made by the method

Publications (2)

Publication Number Publication Date
CA2265198A1 true CA2265198A1 (en) 1999-09-11
CA2265198C CA2265198C (en) 2009-01-27

Family

ID=29712972

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002265198A Expired - Lifetime CA2265198C (en) 1998-03-11 1999-03-10 Method of producing a nicotine medicament and a medicament made by the method

Country Status (1)

Country Link
CA (1) CA2265198C (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9585835B1 (en) 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US9968125B2 (en) 2015-01-09 2018-05-15 Philip Morris Products S.A. Nicotine—diketopiperazine microparticle formulations and methods of making the same
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US11224594B2 (en) 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
US11707432B2 (en) 2015-09-16 2023-07-25 Philip Morris Products S.A. System and method for controlling the harshness of nicotine-based dry powder formulations
WO2023187393A1 (en) 2022-03-31 2023-10-05 Hovione Scientia Limited Inhalation composite and carrier based formulation combination
CN117256920A (en) * 2023-09-27 2023-12-22 东莞市吉纯生物技术有限公司 Solid atomized matter and preparation method thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9968125B2 (en) 2015-01-09 2018-05-15 Philip Morris Products S.A. Nicotine—diketopiperazine microparticle formulations and methods of making the same
US9585835B1 (en) 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US10660883B2 (en) 2015-09-16 2020-05-26 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US11224594B2 (en) 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
US11707432B2 (en) 2015-09-16 2023-07-25 Philip Morris Products S.A. System and method for controlling the harshness of nicotine-based dry powder formulations
WO2023187393A1 (en) 2022-03-31 2023-10-05 Hovione Scientia Limited Inhalation composite and carrier based formulation combination
CN117256920A (en) * 2023-09-27 2023-12-22 东莞市吉纯生物技术有限公司 Solid atomized matter and preparation method thereof

Also Published As

Publication number Publication date
CA2265198C (en) 2009-01-27

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Effective date: 20190311