CA2264870A1 - Apparatus for the characterization of tissue of epithelial lined viscus - Google Patents

Apparatus for the characterization of tissue of epithelial lined viscus

Info

Publication number
CA2264870A1
CA2264870A1 CA002264870A CA2264870A CA2264870A1 CA 2264870 A1 CA2264870 A1 CA 2264870A1 CA 002264870 A CA002264870 A CA 002264870A CA 2264870 A CA2264870 A CA 2264870A CA 2264870 A1 CA2264870 A1 CA 2264870A1
Authority
CA
Canada
Prior art keywords
tissue
viscus
epithelial
under test
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002264870A
Other languages
French (fr)
Other versions
CA2264870C (en
Inventor
Rebecca Richards-Kortum
Michele Follen Mitchell
Urs Utzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2264870A1 publication Critical patent/CA2264870A1/en
Application granted granted Critical
Publication of CA2264870C publication Critical patent/CA2264870C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)

Abstract

A method and apparatus for characterizing tissue of epithelial lined viscus in vivo including, for example, the endocervical canal.
The method comprises illuminating an interior surface of the viscus with electromagnetical radiation wavelengths to produce a plurality of fluorescence intensity spectra detecting a plurality of emission wavelengths from the fluorescence intensity spectra, and characterizing the epithelial viscus tissue as a function of the emission wavelengths. The apparatus includes a light source (17, 18) of emitting a plurality of electromagnetic radiation wavelengths, an optical probe (11) connected to the light source, the probe (11) being adapted to apply the plurality of electromagnetic radiation wavelengths to an interior surface of epithelial viscus tissue under test and to gather fluorescence emitted from the tissue, a detector (24, 26) connected to the probe for detecting at least one fluorescence spectrum emitted from the tissue under test and a programmed computer (29) connected to the detector for processing the at least one fluorescence spectrum according to a predetermined algorithm to characterize the tissue under test.
CA002264870A 1996-08-02 1997-07-31 Apparatus for the characterization of tissue of epithelial lined viscus Expired - Fee Related CA2264870C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69347196A 1996-08-02 1996-08-02
US08/693471 1996-08-02
PCT/US1997/013300 WO1998005253A1 (en) 1996-08-02 1997-07-31 Method and apparatus for the characterization of tissue of epithelial lined viscus

Publications (2)

Publication Number Publication Date
CA2264870A1 true CA2264870A1 (en) 1998-02-12
CA2264870C CA2264870C (en) 2005-07-26

Family

ID=24784792

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002264870A Expired - Fee Related CA2264870C (en) 1996-08-02 1997-07-31 Apparatus for the characterization of tissue of epithelial lined viscus

Country Status (4)

Country Link
EP (1) EP0925015A1 (en)
JP (2) JP2000515407A (en)
CA (1) CA2264870C (en)
WO (1) WO1998005253A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19925210C2 (en) * 1999-06-01 2001-12-20 Alexander Hohla Fiber probe
US20030125630A1 (en) 2001-12-31 2003-07-03 Furnish Simon M. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
EP1495309A1 (en) * 2002-04-05 2005-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US7647092B2 (en) * 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US20040010185A1 (en) * 2002-07-11 2004-01-15 Optical Sensors, Inc. Method for measuring a physiologic parameter using a preferred site
WO2004078044A1 (en) * 2003-03-05 2004-09-16 Infraredx, Inc. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
JP4668624B2 (en) * 2005-01-07 2011-04-13 オリンパス株式会社 Image processing device for esophageal mucosa
EP1738682B1 (en) * 2005-07-01 2008-02-13 Ecole Polytechnique Electronic polarimetric imaging system for colposcopy device
US20070191675A1 (en) * 2006-02-13 2007-08-16 Joel Gerardo Diaz Sanchez Actinic light colposcope and method to detect lesions in the lower female genital tract produced by human papilloma virus using an actinic light colposcope
WO2008115043A1 (en) * 2007-03-22 2008-09-25 Diaz Sanchez Joel Gerardo Combination of a standard vaginal speculum and an excitation system for broad-spectrum variable fluorescence, intended for the diagnosis of diseases of the female genital tract
EP2237190A2 (en) * 2007-08-03 2010-10-06 STI Medical Systems, LLC Computerized image analysis for a acetic acid induced cervical intraepithelial neoplasia
US20120232408A1 (en) * 2009-11-30 2012-09-13 Laura Ann Weller-Brophy Method and Apparatus for Cervical Cancer Screening
JP5323130B2 (en) * 2011-05-26 2013-10-23 富士フイルム株式会社 Fluorescence analyzer and fluorescence analysis method
EP2712534A4 (en) 2011-07-15 2015-03-04 Olympus Medical Systems Corp Probe
US11446055B1 (en) 2018-10-18 2022-09-20 Lumoptik, Inc. Light assisted needle placement system and method
WO2022196493A1 (en) * 2021-03-17 2022-09-22 テルモ株式会社 Program, information processing method, image diagnosis device, and trained model generation method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
US5456260A (en) * 1994-04-05 1995-10-10 The General Hospital Corporation Fluorescence detection of cell proliferation
US5450857A (en) * 1994-05-19 1995-09-19 Board Of Regents, The University Of Texas System Method for the diagnosis of cervical changes
ATE242999T1 (en) * 1994-07-14 2003-07-15 Washington Res Found DEVICE FOR DETECTING BARRETT METAPLASIA IN THE ESOPHAUS
US5697373A (en) * 1995-03-14 1997-12-16 Board Of Regents, The University Of Texas System Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies

Also Published As

Publication number Publication date
JP2008100064A (en) 2008-05-01
CA2264870C (en) 2005-07-26
WO1998005253A1 (en) 1998-02-12
JP2000515407A (en) 2000-11-21
EP0925015A1 (en) 1999-06-30

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130731