CA2259318A1 - Pressure-mediated binding of biomolecular complexes - Google Patents

Pressure-mediated binding of biomolecular complexes

Info

Publication number
CA2259318A1
CA2259318A1 CA002259318A CA2259318A CA2259318A1 CA 2259318 A1 CA2259318 A1 CA 2259318A1 CA 002259318 A CA002259318 A CA 002259318A CA 2259318 A CA2259318 A CA 2259318A CA 2259318 A1 CA2259318 A1 CA 2259318A1
Authority
CA
Canada
Prior art keywords
pressure
analyte
enable
mediated
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002259318A
Other languages
French (fr)
Other versions
CA2259318C (en
Inventor
Gerald J. Litt
James A. Laugharn, Jr.
David J. Green
Robert A. Hess
Henry Paulus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioseq Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1997/011198 external-priority patent/WO1998000032A1/en
Publication of CA2259318A1 publication Critical patent/CA2259318A1/en
Application granted granted Critical
Publication of CA2259318C publication Critical patent/CA2259318C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
    • C11B7/0008—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents
    • C11B7/005—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents in solvents used at superatmospheric pressures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to (1) pressure-mediated dissociation of an analyte complexed with an endogenous binding partner to enable detection of a complex formed from the analyte and an exogenous binding factor, (2) pressure-mediated association of an analyte and an exogenous binding partner to enable more rapid and/or more sensitive detection of an analyte, and (3) pressure-mediated association and dissociation of biomolecular complexes to enable separation of one biomolecule from a complex mixture. Pressure can be used to improve assays by dissociating endogenous analyte complexes and improving assay speed and sensitivity by associating the analyte molecules with exogenously supplied binding partners. Pressure can also be used to improve the separation of compounds from contaminated mixtures.
CA002259318A 1996-07-02 1997-07-01 Pressure-mediated binding of biomolecular complexes Expired - Fee Related CA2259318C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2056296P 1996-07-02 1996-07-02
US60/020,562 1996-07-02
US4459597P 1997-04-22 1997-04-22
US60/044,595 1997-04-22
PCT/US1997/011198 WO1998000032A1 (en) 1996-07-02 1997-07-01 Pressure-mediated binding of biomolecular complexes

Publications (2)

Publication Number Publication Date
CA2259318A1 true CA2259318A1 (en) 1998-01-08
CA2259318C CA2259318C (en) 2007-06-26

Family

ID=38279109

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002259318A Expired - Fee Related CA2259318C (en) 1996-07-02 1997-07-01 Pressure-mediated binding of biomolecular complexes

Country Status (1)

Country Link
CA (1) CA2259318C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10488307B2 (en) 2017-12-12 2019-11-26 Dignity Health Systems, devices, and methods for improved tissue treatment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10488307B2 (en) 2017-12-12 2019-11-26 Dignity Health Systems, devices, and methods for improved tissue treatment

Also Published As

Publication number Publication date
CA2259318C (en) 2007-06-26

Similar Documents

Publication Publication Date Title
AU3643797A (en) Pressure-mediated binding of biomolecular complexes
WO1999022242A3 (en) Measurement of glycated hemoglobin
CA2256943A1 (en) General purpose structure of an analytical element and its application for analyte determination
DE60136034D1 (en) Molecular modification assays
AU1882688A (en) Non-metal colloidal particle immunoassay
EP0980517A4 (en) Detachable-element assay device
CA2096389A1 (en) Analysis of samples by capillary electrophoretic immunosubtraction
EP1418430A3 (en) A homogeneous assay for determining analyte
AU2044795A (en) Reagents for specific binding assays
AU583737B2 (en) Process and reagent for the specific determination of fructosamine
KR960029789A (en) Kits for immunological analysis of in vivo substances and immunological analysis methods
WO2003040172A3 (en) Methods and reagents for peptide-bir interaction screens
AU3059499A (en) Solid-phase method for antigen and antibody determinations in bloodgroup serology, and test kit
CA2341262A1 (en) Chemiluminescent immunoassay for detection of antibodies to various viruses
AU2875097A (en) Increasing the sensitivity in the immunochemical determination of an analyte
EP0399464A3 (en) Assay method for a substance with a specific sugar chain
CA2259318A1 (en) Pressure-mediated binding of biomolecular complexes
WO2003019194A3 (en) Displacement assay for detecting ligate-ligand association events
MY106963A (en) Agglutination assay.
DE60022642D1 (en) IDENTIFICATION OF LIGANDS FOR "ORPHANIC" RECEPTORS USING MASS SPECTROMETRY
WO2002057743A3 (en) Methods of analyzing and sorting one or more analytes
ES2070129T3 (en) AGGLUTINATION TEST.
CA2123069A1 (en) Immunoassay for analytes in samples using alkylating agents
EP1203957A3 (en) Multi-analyte immunoassay
AU3106589A (en) Agent, for immunochemical assays, containing amine oxides

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150702