CA2257895A1 - Fourier detection of species migrating in a microchannel - Google Patents

Fourier detection of species migrating in a microchannel

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Publication number
CA2257895A1
CA2257895A1 CA002257895A CA2257895A CA2257895A1 CA 2257895 A1 CA2257895 A1 CA 2257895A1 CA 002257895 A CA002257895 A CA 002257895A CA 2257895 A CA2257895 A CA 2257895A CA 2257895 A1 CA2257895 A1 CA 2257895A1
Authority
CA
Canada
Prior art keywords
species
channel
microchannel
electrophoretic
photodetector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002257895A
Other languages
French (fr)
Other versions
CA2257895C (en
Inventor
J. Wallace Parce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caliper Life Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/683,080 external-priority patent/US5699157A/en
Application filed by Individual filed Critical Individual
Publication of CA2257895A1 publication Critical patent/CA2257895A1/en
Application granted granted Critical
Publication of CA2257895C publication Critical patent/CA2257895C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The present invention provides a microfluidic system (100) for fast, accurate and low cost electrophoretic analysis of materials in the fields of chemistry, biochemistry, biotechnology, molecular biology and numerous other fields. Light from periodically spaced regions along a channel (110) in the microfluidic system are received by the photodetector (130). The intensity of light received by the photodetector is modulated by the movement of species bands (123) through the channel under electrophoretic forces. By Fourier analysis, the velocity of each species band (123) is determined and the identification of the species is made by its electrophoretic mobility in the channel (110).
CA002257895A 1996-07-16 1997-07-14 Fourier detection of species migrating in a microchannel Expired - Fee Related CA2257895C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/683,080 US5699157A (en) 1996-07-16 1996-07-16 Fourier detection of species migrating in a microchannel
US08/683,080 1996-07-16
PCT/US1997/012262 WO1998002728A1 (en) 1996-07-16 1997-07-14 Fourier detection of species migrating in a microchannel

Publications (2)

Publication Number Publication Date
CA2257895A1 true CA2257895A1 (en) 1998-01-22
CA2257895C CA2257895C (en) 2005-10-04

Family

ID=35395957

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002257895A Expired - Fee Related CA2257895C (en) 1996-07-16 1997-07-14 Fourier detection of species migrating in a microchannel

Country Status (1)

Country Link
CA (1) CA2257895C (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7975531B2 (en) 2005-03-18 2011-07-12 Nanyang Technological University Microfluidic sensor for interfacial tension measurement and method for measuring interfacial tension
CN113075113A (en) * 2014-12-09 2021-07-06 伯克利之光生命科技公司 Automated detection and repositioning of micro-objects in microfluidic devices

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7975531B2 (en) 2005-03-18 2011-07-12 Nanyang Technological University Microfluidic sensor for interfacial tension measurement and method for measuring interfacial tension
CN113075113A (en) * 2014-12-09 2021-07-06 伯克利之光生命科技公司 Automated detection and repositioning of micro-objects in microfluidic devices

Also Published As

Publication number Publication date
CA2257895C (en) 2005-10-04

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