CA2254528A1 - Treatment of ischemia reperfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction - Google Patents
Treatment of ischemia reperfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction Download PDFInfo
- Publication number
- CA2254528A1 CA2254528A1 CA 2254528 CA2254528A CA2254528A1 CA 2254528 A1 CA2254528 A1 CA 2254528A1 CA 2254528 CA2254528 CA 2254528 CA 2254528 A CA2254528 A CA 2254528A CA 2254528 A1 CA2254528 A1 CA 2254528A1
- Authority
- CA
- Canada
- Prior art keywords
- treatment
- reperfusion injury
- heart failure
- ischemia reperfusion
- myocardial infarction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Compositions and methods for treatment and prevention of ischemia-related conditions, such as ischemia reperfusion injury and cellular dysfunction, are disclosed.
The methods are directed to administering pharmaceutical compositions containing at least one compound derived from vitamin B6, such as pyridoxal-5'-phosphate, pyridoxine, pyridoxal, and pyridoxamine.
The methods are directed to administering pharmaceutical compositions containing at least one compound derived from vitamin B6, such as pyridoxal-5'-phosphate, pyridoxine, pyridoxal, and pyridoxamine.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11227798A | 1998-07-09 | 1998-07-09 | |
US09/112,277 | 1998-07-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2254528A1 true CA2254528A1 (en) | 2000-01-09 |
CA2254528C CA2254528C (en) | 2007-07-17 |
Family
ID=22343046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2254528 Expired - Fee Related CA2254528C (en) | 1998-07-09 | 1998-11-26 | Treatment of ischemia reperfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP2000026295A (en) |
AU (2) | AU759824B2 (en) |
CA (1) | CA2254528C (en) |
NZ (1) | NZ333023A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1531157A1 (en) * | 2000-02-29 | 2005-05-18 | Medicure International Inc. | Cardioprotective phosphonates |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001237185B2 (en) * | 2000-02-29 | 2006-02-02 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ222664A (en) * | 1986-11-29 | 1990-06-26 | Vesta Med Pty Ltd | Pharmaceutical compositions containing pyridoxal as a source of vitamin b6 |
JPH09221425A (en) * | 1996-02-13 | 1997-08-26 | Taiho Yakuhin Kogyo Kk | Thiol protease inhibitor |
-
1998
- 1998-11-26 NZ NZ33302398A patent/NZ333023A/en unknown
- 1998-11-26 CA CA 2254528 patent/CA2254528C/en not_active Expired - Fee Related
- 1998-11-27 JP JP10338077A patent/JP2000026295A/en active Pending
- 1998-11-27 AU AU94210/98A patent/AU759824B2/en not_active Revoked
-
2007
- 2007-06-06 AU AU2007202621A patent/AU2007202621A1/en not_active Ceased
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1531157A1 (en) * | 2000-02-29 | 2005-05-18 | Medicure International Inc. | Cardioprotective phosphonates |
Also Published As
Publication number | Publication date |
---|---|
AU2007202621A1 (en) | 2007-06-28 |
JP2000026295A (en) | 2000-01-25 |
NZ333023A (en) | 2000-08-25 |
AU759824B2 (en) | 2003-05-01 |
CA2254528C (en) | 2007-07-17 |
AU9421098A (en) | 2000-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |