CA2252038A1 - Buccal polar spray or capsule - Google Patents

Buccal polar spray or capsule

Info

Publication number
CA2252038A1
CA2252038A1 CA002252038A CA2252038A CA2252038A1 CA 2252038 A1 CA2252038 A1 CA 2252038A1 CA 002252038 A CA002252038 A CA 002252038A CA 2252038 A CA2252038 A CA 2252038A CA 2252038 A1 CA2252038 A1 CA 2252038A1
Authority
CA
Canada
Prior art keywords
capsule
polar solvent
invention comprises
buccal
flavoring agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002252038A
Other languages
French (fr)
Other versions
CA2252038C (en
Inventor
Harry A. Dugger, Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUDA Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1997/002793 external-priority patent/WO1997038662A2/en
Publication of CA2252038A1 publication Critical patent/CA2252038A1/en
Application granted granted Critical
Publication of CA2252038C publication Critical patent/CA2252038C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)

Abstract

A buccal aerosol spray or capsule using a polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect.
The buccal aerosol spray of the invention comprises: polar solvent 75-99,8 % compound 0.0025-40 %, flavoring agent 0.05-5 %. The soft bite gelatin capsule of the invention comprises as comprising as fill composition: polar solvent 50-99,8 %, emulsifier 0-20 %, active compound 0.0003-26 %, and flavoring agent 0.05-60 %.
CA002252038A 1996-04-12 1997-02-21 Buccal polar spray or capsule Expired - Fee Related CA2252038C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63006596A 1996-04-12 1996-04-12
US08/630,065 1996-04-12
PCT/US1997/002793 WO1997038662A2 (en) 1996-04-12 1997-02-21 Buccal polar spray or capsule

Publications (2)

Publication Number Publication Date
CA2252038A1 true CA2252038A1 (en) 1997-10-23
CA2252038C CA2252038C (en) 2006-10-10

Family

ID=37114287

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002252038A Expired - Fee Related CA2252038C (en) 1996-04-12 1997-02-21 Buccal polar spray or capsule

Country Status (1)

Country Link
CA (1) CA2252038C (en)

Also Published As

Publication number Publication date
CA2252038C (en) 2006-10-10

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20170221