CA2248189A1 - System for determining analyte concentration - Google Patents
System for determining analyte concentrationInfo
- Publication number
- CA2248189A1 CA2248189A1 CA002248189A CA2248189A CA2248189A1 CA 2248189 A1 CA2248189 A1 CA 2248189A1 CA 002248189 A CA002248189 A CA 002248189A CA 2248189 A CA2248189 A CA 2248189A CA 2248189 A1 CA2248189 A1 CA 2248189A1
- Authority
- CA
- Canada
- Prior art keywords
- analyte concentration
- optical detection
- determining analyte
- detection system
- fluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012491 analyte Substances 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 3
- 238000000159 protein binding assay Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The present invention relates to a system (80) for determining analyte concentration. The system (80) includes an optical detection system (92) that detects fluorescence from fluorescent binding assays in a biosensor (88). A processing system (96) may be used to determine analyte concentration from the fluorescence detected by the optical detection system (92). The optical detection system (92) may include photodetectors with or without in series lenses.
Alternatively, a CCD camera (146) may be used.
Alternatively, a CCD camera (146) may be used.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1368496P | 1996-03-19 | 1996-03-19 | |
US60/013,684 | 1996-03-19 | ||
PCT/US1997/004377 WO1997035181A1 (en) | 1996-03-19 | 1997-03-19 | System for determining analyte concentration |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2248189A1 true CA2248189A1 (en) | 1997-09-25 |
CA2248189C CA2248189C (en) | 2007-05-29 |
Family
ID=38150711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002248189A Expired - Lifetime CA2248189C (en) | 1996-03-19 | 1997-03-19 | System for determining analyte concentration |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2248189C (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8300993B2 (en) | 2009-03-02 | 2012-10-30 | Mbio Diagnostics, Inc. | Waveguide with integrated lens |
US8331751B2 (en) | 2009-03-02 | 2012-12-11 | mBio Diagnositcs, Inc. | Planar optical waveguide with core of low-index-of-refraction interrogation medium |
US8586347B2 (en) | 2010-09-15 | 2013-11-19 | Mbio Diagnostics, Inc. | System and method for detecting multiple molecules in one assay |
US9658222B2 (en) | 2009-03-02 | 2017-05-23 | Mbio Diagnostics, Inc. | Planar waveguide based cartridges and associated methods for detecting target analyte |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9212995B2 (en) | 2009-03-02 | 2015-12-15 | Mbio Diagnostics, Inc. | System and method for detecting multiple molecules in one assay |
-
1997
- 1997-03-19 CA CA002248189A patent/CA2248189C/en not_active Expired - Lifetime
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8300993B2 (en) | 2009-03-02 | 2012-10-30 | Mbio Diagnostics, Inc. | Waveguide with integrated lens |
US8331751B2 (en) | 2009-03-02 | 2012-12-11 | mBio Diagnositcs, Inc. | Planar optical waveguide with core of low-index-of-refraction interrogation medium |
US8606066B2 (en) | 2009-03-02 | 2013-12-10 | Mbio Diagnostics, Inc. | Planar optical waveguide with core of low-index-of-refraction interrogation medium |
US9658222B2 (en) | 2009-03-02 | 2017-05-23 | Mbio Diagnostics, Inc. | Planar waveguide based cartridges and associated methods for detecting target analyte |
US8586347B2 (en) | 2010-09-15 | 2013-11-19 | Mbio Diagnostics, Inc. | System and method for detecting multiple molecules in one assay |
Also Published As
Publication number | Publication date |
---|---|
CA2248189C (en) | 2007-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20170320 |