CA2245728A1 - Isoquinoline derivatives and drugs - Google Patents

Isoquinoline derivatives and drugs

Info

Publication number
CA2245728A1
CA2245728A1 CA 2245728 CA2245728A CA2245728A1 CA 2245728 A1 CA2245728 A1 CA 2245728A1 CA 2245728 CA2245728 CA 2245728 CA 2245728 A CA2245728 A CA 2245728A CA 2245728 A1 CA2245728 A1 CA 2245728A1
Authority
CA
Canada
Prior art keywords
hydroxy
halogen
compound
amino group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2245728
Other languages
French (fr)
Other versions
CA2245728C (en
Inventor
Akira Matsuura
Takushi Matsuzaki
Hiroyoshi Hidaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
D Western Therapeutics Institute
Original Assignee
Nippon Shinyaku Co., Ltd.
Akira Matsuura
Takushi Matsuzaki
Hiroyoshi Hidaka
D. Western Therapeutics Institute
Kowa Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co., Ltd., Akira Matsuura, Takushi Matsuzaki, Hiroyoshi Hidaka, D. Western Therapeutics Institute, Kowa Co., Ltd. filed Critical Nippon Shinyaku Co., Ltd.
Priority claimed from PCT/JP1997/000240 external-priority patent/WO1997028130A1/en
Publication of CA2245728A1 publication Critical patent/CA2245728A1/en
Application granted granted Critical
Publication of CA2245728C publication Critical patent/CA2245728C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a compound of the following general formula [I] or a medicinally acceptable salt thereof, or a solvate thereof, (see formula I) wherein R1 represents alkyl, alkenyl, alkynyl, alkoxy, hydroxy, cyano, or halogen; R2 represents hydrogen, hydroxy, or halogen; R3 represents hydrogen, alkyl, or amidino; Ring A represents a 5 to 11-membered cyclic amino group which may be substituted, which cyclic amino group may be bridged between two carbon atoms in optional positions.
The compound of this invention is useful for the prevention or treatment of cerebral tissue impairment due to the vasospasm following cerebral hemorrhage.
CA 2245728 1996-02-02 1997-01-31 Isoquinoline derivatives and drugs Expired - Lifetime CA2245728C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP8/17946 1996-02-02
JP1794696 1996-02-02
JP27588696 1996-10-18
JP8/275886 1996-10-18
PCT/JP1997/000240 WO1997028130A1 (en) 1996-02-02 1997-01-31 Isoquinoline derivatives and drugs

Publications (2)

Publication Number Publication Date
CA2245728A1 true CA2245728A1 (en) 1997-08-07
CA2245728C CA2245728C (en) 2006-12-05

Family

ID=29424195

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2245728 Expired - Lifetime CA2245728C (en) 1996-02-02 1997-01-31 Isoquinoline derivatives and drugs

Country Status (1)

Country Link
CA (1) CA2245728C (en)

Also Published As

Publication number Publication date
CA2245728C (en) 2006-12-05

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Legal Events

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EEER Examination request
MKEX Expiry

Effective date: 20170131